Vascular Imaging Enhancer
A vascular imaging and enhancing agent technology, applied in echo/ultrasonic imaging agents and other directions, can solve the problems of long time delay for penetration promotion and low imaging quality, and achieve the advantages of short time delay for penetration promotion, simple mixing process, and improved contrast. Effect
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Embodiment 1-6
[0035] According to formulas 1-6 and specific preparation methods, the blood vessel imaging enhancers of Examples 1-6 of the present application were prepared. Rats weighing 190-200 g were anesthetized by intraperitoneal injection of anesthesia (2% chloral hydrate mixed with 10% ulax, 1ml / 100g body weight), the hair on the back was cut off, and the rest of the hair was carefully removed with depilatory cream. Select the action area with a diameter of about 1 cm on the back of the rat, apply the vascular imaging enhancer of the present invention evenly, and act for 1 to 2 minutes, then use a visible-near-infrared optical fiber spectrometer to detect the reflectivity of the infrared reflected light of the back skin of the rat, and compare it with the untreated one. The rat skin (blank group) coated with vascular imaging enhancer is compared to investigate the effect of vascular imaging enhancer, and the results of the comparison test are shown in Table 2:
[0036] Table 2 Infrar...
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