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143 results about "Vascular imaging" patented technology

Intravenous infusion puncture blood vessel imaging glasses equipment and application method thereof

The invention relates to the technical field of medical instruments, and discloses intravenous infusion puncture angiography glasses equipment and an application method thereof. The equipment comprises an infrared imaging module, an image processing module, a data communication module, a correction early warning module and a display module. The infrared imaging module collects original blood vessel image data, the image processing module generates blood vessel positioning information, the data communication module interacts with a background server, the correction early warning module generates an early warning prompt according to a server instruction, and the display module displays related information in an overlapping mode. By accurately positioning the blood vessel and providing puncture guidance, the equipment improves the success rate of venous transfusion puncture, reduces the pain of a patient, improves the medical working efficiency, reduces the medical cost, guarantees the medical safety, and is suitable for various venous transfusion puncture scenes, especially patients with poor blood vessel conditions.
Owner:ZHEJIANG UNIV

Human body peripheral blood vessel photoacoustic three-dimensional imaging device and imaging method thereof

The invention discloses a human body peripheral blood vessel photoacoustic three-dimensional imaging device and an imaging method thereof, and belongs to the field of blood vessel imaging. Through high resolution and functional monitoring capability of photoacoustic imaging, detailed blood vessel structure and blood flow dynamic information are provided, and early recognition and treatment effect evaluation of common lesions such as diabetic foot and peripheral artery diseases are promoted; meanwhile, a mechanical system is adopted, so that the detection front end with relatively high quality can be borne, and stable operation is realized, and a relatively good photoacoustic imaging result is obtained; the system has a highly stable accurate scanning imaging mode, and is convenient for multiple imaging modes of clinical application; through the arrangement of the imaging water tank and the lifting structure of the imaging water tank, switching of imaging modes in a limited space can be ensured, so that the device can be suitable for the layout of a portal type three-dimensional moving device. The system is expected to promote the portability of equipment, reduce the research and development cost of the equipment, be widely applied to clinical practice and community medical treatment, and improve the disease management level.
Owner:PEKING UNIV

Blood vessel imaging method, system and device based on ultrasonic positioning and storage medium

The embodiment of the invention provides an angiography method, system and device based on ultrasonic positioning and a storage medium, and belongs to the technical field of ultrasonic medical detection. Firstly, an ultrasonic probe is adopted to scan a current area to obtain ultrasonic data, a Doppler imaging technology is adopted to process the ultrasonic data to obtain a Doppler blood vessel image of the current area, then whether the current area is a target area or not is rapidly judged according to the Doppler blood vessel image, and after the target area is rapidly determined, the target area is determined. And performing microbubble contrast operation on the blood vessel of the target area, and scanning the target area after the microbubble contrast operation by adopting an ultrasonic positioning microscope technology, so as to obtain a high-precision blood vessel image of the target area. The target area is rapidly positioned through the Doppler imaging technology, then the blood vessel image is collected in the target area through the ultrasonic positioning microscope technology based on microbubble radiography, the efficiency of the blood vessel image collection process of the target area is improved, and meanwhile the blood vessel image precision is improved.
Owner:CENT SOUTH UNIV +1

Vascular surgery image intelligent optimization method

The invention discloses a vascular surgery image intelligent optimization method, and relates to the field of medical image intelligent processing. According to the technical scheme, the method comprises the following steps: collecting original image data according to a vascular surgical image, extracting image features through a deep convolutional neural network CNN, constructing an angiography lesion sensitivity map, generating a sensitivity initial weight map by using the sensitivity map, and constructing a vascular structure topological map based on the initial weight map; and carrying out sensitivity propagation and correction by adopting a graph neural network to obtain a corrected sensitivity weight graph, and carrying out local adaptive image enhancement processing according to the corrected sensitivity weight graph to obtain an intelligently optimized image. The problem that a lesion area is not prone to protruding in angiography is solved, and the diagnosis accuracy is improved.
Owner:QILU HOSPITAL(QINGDAO) CHEELOO COLLEGE OF MEDICINE SHANDONG UNIV

Patient venipuncture auxiliary guiding device based on intelligent visual identification

The invention discloses a patient venipuncture auxiliary guiding device based on intelligent visual identification, the device is provided with a limb placing plate, the limb placing plate comprises a bottom plate and a silica gel lining plate, and a comfortable placing position can be provided for the limbs of a patient. The linear guide rail is installed on the right side of the top of the limb placing plate. The electric control sliding block can slide on the rail. The Z-axis lifting mechanism is connected with the electric control sliding block, the servo motor drives the lead screw to rotate, and the movable sleeve drives the right-angle type blood vessel imaging mechanism to ascend and descend in the vertical direction. The right-angle type blood vessel imaging mechanism is composed of two supports, a top blood vessel imager and a side blood vessel imager are embedded in the supports, imaging ports face the upper surface and the side face of the limb to be punctured respectively, and the direction and the depth of blood vessels can be clearly shown. In addition, a controller is installed on the side wall of the bottom plate and can control an electric control linear guide rail, an electric control sliding block and a servo motor, medical workers are assisted in accurately finding the blood vessel position, and the success rate of venipuncture is increased.
Owner:TONGXIANG SECOND PEOPLES HOSPITAL

Venipuncture auxiliary device based on visualization technology

The invention relates to the technical field of medical assistance, in particular to a venipuncture assisting device based on a visualization technology, which comprises a base, fixing pieces are arranged on both sides of the base, adjusting assemblies are arranged at the joints of the two fixing pieces and the base, a binding assembly is arranged in the middle between the two fixing pieces, and an air bag assembly is arranged on the binding assembly. The fixing piece on one side is fixedly connected with an infrared blood vessel imager, the infrared blood vessel imager is in signal connection with a control system, the fixing piece on the other side is provided with a projector, the air bag assembly comprises symmetrical first air bags, the inner sides of the two fixing pieces are fixedly connected with a plurality of second air bags, and the second air bags on the same side are located at the two ends respectively. By means of the design of the air bag system and the utilization of the characteristic of air flow, the dynamic constraint adjustment in the puncture process is achieved while the puncture constraint comfort of a patient is improved, and the puncture accuracy is improved.
Owner:南昌大学第一附属医院

Cardiovascular assessment of patients suspected of having COVID-19

Systems and methods for assessing cardiovascular disease of a patient are provided. Patient data of the patient is received. The patient data may include one or more input medical images of a chest of the patient, results of an assessment of a lung disease performed based on the one or more input medical images, demographic and clinical data of the patient, and cardiovascular imaging exams of the patient. One or more risk scores are computed for the patient based on the patient data using a trained machine learning based network.
Owner:SIEMENS HEALTHINEERS AG

Multi-mode whole body blood vessel magnetic resonance imaging method and device

PendingCN120678410AImage enhancementMagnetic measurementsVascular magnetic resonance imagingSuperparamagnetic iron oxide
The invention discloses a multi-mode whole-body blood vessel magnetic resonance imaging method and device, and the method comprises the steps: displaying prompt information for carrying out the cascade wrapping of a whole-body magnetic resonance coil and the input of a contrast agent for a target object, and enabling the contrast agent to be polysaccharide superparamagnetic iron oxide; setting a signal mark point on the constructed whole body positioning image and configuring a multi-modal imaging sequence; emitting a magnetic resonance radio frequency pulse, and receiving a coil electric signal transmitted by the whole body magnetic resonance coil; determining the signal intensity of each set signal mark point according to the coil electric signal; when the signal intensity is larger than a preset threshold value, whole-body blood vessel scanning is conducted on the target object through the multi-mode imaging sequence; and performing image reconstruction according to the scanned target image sequence to generate a whole body blood vessel image. By adopting the embodiment of the invention, one-stop imaging of large and small blood vessels of the whole body can be realized at one time by utilizing a scanning mode of cascading wrapping of the whole body magnetic resonance coil, so that the scanning time is greatly shortened, and the blood vessel imaging efficiency is improved.
Owner:吴敏 +2

Ophthalmology laser operation auxiliary positioning method, storage medium and equipment

InactiveCN120346048ALaser surgeryOphthalmology departmentIntraoperative bleeding
The invention relates to an ophthalmology laser operation auxiliary positioning method, a storage medium and equipment, and relates to the technical field of ophthalmology laser operations. The method comprises the following steps: acquiring OCTA image data of blood vessels around the iris of a patient through optical coherence tomography angiography; processing the OCTA image data to identify blood vessel condition information; based on the blood vessel condition information, safe area coordinates avoiding the blood vessel position are generated; the safety zone coordinates are mapped to a surgical navigation system to guide implementation of a laser drilling operation. According to the technical scheme, OCTA imaging and processing are carried out on the blood vessels around the iris of the patient, the high-risk blood vessel position can be effectively recognized, and the safe punching area coordinates avoiding the blood vessels are generated based on the high-risk blood vessel position, so that the risk of complications such as bleeding in an operation is greatly reduced, and the operation efficiency is improved. And the safety of the closed-angle glaucoma laser peripheral iris resection is improved.
Owner:BEIJING SHIJITAN HOSPITAL CAPITAL MEDICAL UNIVERSITY

Angiocardiography high-precision angiography enhancement method and system

ActiveCN121563781AImage enhancementImage analysisImage subtractionQT interval
The invention relates to the technical field of image enhancement, in particular to an angiocardiography high-precision angiography enhancement method and system. The method comprises the steps that an ECG curve of electrocardiosignals before and after contrast agent injection of a patient and a blood vessel image are obtained; determining the compressible degree of each wave band according to the change of different wave bands and the change of the heart rate in the QT interval before and after the contrast agent is injected; determining the increment duration of each wave band in combination with the standard duration, the actual duration and the compressible degree; performing standardized adjustment on the ECG time phase of each frame of blood vessel image in combination with the increment time length and the actual time length of each wave band to obtain a standard time phase; determining a mask matched with each negative film according to the standard time phases of the negative films and the masks; and carrying out image subtraction on each negative film and the matched mask, and carrying out angiography enhancement processing. The blood vessel imaging precision after digital subtraction can be improved, the blood vessel artifact phenomenon is reduced, and the blood vessel imaging precision and reliability are enhanced.
Owner:SHANGHAI SONGJIANG DISTRICT CENTRAL HOSPITAL

Peripheral blood vessel imaging method and system based on ultrasonic tomography and storage medium

The invention belongs to the technical field of ultrasonic angiography, and particularly relates to a peripheral angiography method and system based on ultrasonic tomography and a storage medium. Acquiring an image of a to-be-detected part through an ultrasonic tomography system to obtain a plurality of frames of three-dimensional cross section image sequences; synchronously acquiring pulse signals; processing the three-dimensional cross section image sequence by adopting a target detection neural network, and outputting a preliminary observation value of the blood vessel position; sequentially performing optimal state estimation on the blood vessel position of each frame of three-dimensional cross section image based on a Kalman filtering algorithm, and outputting the optimal blood vessel position estimation of each frame; wherein the initial observation value of the blood vessel position serves as an observation value of Kalman filtering, and a state transition equation of a Kalman filtering algorithm is constructed according to the blood vessel position, the blood flow speed and the pulse signal; and according to the optimized three-dimensional cross section image sequence, reconstructing to obtain a dynamic three-dimensional blood vessel model. Dynamic artifact suppression and state smoothing are achieved based on the pulse signals, and image definition is provided.
Owner:HUAZHONG UNIV OF SCI & TECH

Functional stenosis assessment from vascular imaging

The present disclosure provides to generate ground truth data for training a machine learning (ML) model to infer pressure information (e.g., a pressure curve, a pressure ratio, or the like) for a cardiac artery from border segmentations generated from images of the cardiac artery. The ground truth data can comprise vessel and / or lumen segmentations for several cardiac arteries and associated pressure information for the cardiac arteries. The vessel and / or lumen segmentations can be generated from images from different image modalities (e.g., IVUS, angiographic, CT, etc.). Further, some of the associated pressure information can be based on measured pressure information (e.g., using a pressure sensing catheter) while other associated pressure information can be derived from the vessel and / or lumen border segmentations using numerical analysis techniques (e.g., CFD, or the like).
Owner:BOSTON SCIENTIFIC SCIMED INC

Artificial artery and vein arm vascular imaging methods and related devices

This application relates to a method and related apparatus for vascular imaging of an artificial artery and vein arm. The method includes the following steps: acquiring superficial near-infrared images and deep near-infrared images; layering the deep near-infrared images based on the superficial near-infrared images to obtain venous and arterial image information; acquiring pulsed Doppler ultrasound images and obtaining the relative positional relationship between the venous and arterial vessels based on the pulsed Doppler ultrasound images; calculating theoretical arterial image information based on the relative positional relationship from the venous image information; matching the theoretical arterial image and the arterial image, and completing the arterial image based on the matching result. This application has the advantage of improving the imaging effect of vascular imaging instruments.
Owner:DAITE INTELLIGENT TECH (SHANGHAI) CO LTD +1

Painless blood vessel puncture device with intelligent positioning function

The invention relates to the technical field of medical instruments, in particular to a painless blood vessel puncture device with an intelligent positioning function, which comprises a base, a blood vessel imaging instrument is arranged on the base, and an auxiliary mechanism is arranged on the base; the auxiliary mechanism comprises an annular mounting frame, six stretching pieces are evenly arranged in the mounting frame in the circumferential direction, each stretching piece comprises a pull rod, a telescopic belt is arranged in the mounting frame and arranged on the pull rod of the six stretching pieces in a sleeving mode, so that the telescopic belt is hexagonal, the pull rod is connected with a separation piece, and the separation piece is connected with a pull rod. The separating piece can drive the pull rod to reciprocate in the axial direction of the mounting frame, the pull rod is connected with a pressing piece, and the pressing piece can drive the pull rod to reciprocate in the radial direction of the mounting frame; the stretching piece on the top side is connected with a liquid spraying mechanism, the liquid spraying mechanism comprises a disinfection piece and a pain relieving piece, and disinfection alcohol is contained in the disinfection piece.
Owner:AFFILIATED HOSPITAL OF ZUNYI UNIV

Three-dimensional reconstruction and quantitative analysis consistency control method and system of multi-center CT angiography data, electronic equipment and storage medium

The application provides a three-dimensional reconstruction and quantitative analysis consistency control method and system of multi-center CT blood vessel imaging data, an electronic device and a storage medium, and relates to the technical field of medical image processing. The method comprises the following steps: first, synchronously acquiring original projection data of multi-center CT blood vessel imaging, blood vessel center line topological data and blood vessel respiratory motion displacement data, generating a blood vessel deformation correction matrix based on the respiratory motion displacement data, and dynamically registering the blood vessel center line data by using the matrix to obtain corrected center line data; then, inputting the corrected center line data and the original projection data into a multi-modal feature fusion network for three-dimensional reconstruction to generate an initial blood vessel model; then, performing morphological parameter quantitative analysis on the initial model; finally, comparing the analysis result with a clinical standard and adjusting the model parameters to output a target blood vessel three-dimensional model. The application improves the geometric accuracy and clinical applicability of the blood vessel model reconstruction.
Owner:SHENG EN (BEIJING) PHARM TECH CO LTD

Manufacturing method of bionic blood vessel model and bionic blood vessel model

The invention relates to a manufacturing method of a bionic blood vessel model and the bionic blood vessel model.The manufacturing method of the bionic blood vessel model comprises the steps that a three-dimensional computer model of a blood vessel lumen is constructed according to blood vessel image data; according to a three-dimensional computer model of a blood vessel lumen, a water-soluble polyvinyl alcohol material is adopted to manufacture a water-soluble inner core through a 3D printing technology; the water-soluble inner core is subjected to operation for N times or less, wherein N is larger than or equal to 1; the outer surface of the water-soluble inner core is evenly covered with a polyvinyl alcohol solution; the water-soluble inner core covered with the polyvinyl alcohol solution is subjected to at least one time of freeze thawing treatment, so that the polyvinyl alcohol solution is solidified into polyvinyl alcohol hydrogel; after N times of operation are completed, the water-soluble inner core covered with the polyvinyl alcohol hydrogel is soaked in ultrapure water so that the water-soluble inner core can be dissolved, and therefore the bionic blood vessel model with the good shape and mechanical property is obtained.
Owner:THE FIRST AFFILIATED HOSPITAL OF TSINGHUA UNIV

Nanoparticle with fluorescence enhancement performance and preparation method and application thereof

This invention discloses a fluorescence-enhancing nanoparticle, its preparation method, and its applications, relating to the fields of organic fluorescent molecules and bioimaging technology. The nanoparticle comprises: NIR-II fluorescent molecules and an amphiphilic polymer encapsulating the NIR-II fluorescent molecules; the amphiphilic polymer has a hydrophilic segment and a rigid hydrophobic segment. The nanoparticle of this invention, based on "carrier microenvironment engineering," utilizes the rigid confinement and interfacial isolation provided by the amphiphilic polymer with the rigid hydrophobic segment for dual brightening, serving as a universal brightening platform applicable to various NIR-II fluorescent molecules. This nanoparticle can significantly improve aqueous phase quantum yield, enhance contrast and resolution in in vivo vascular imaging, improve deep tissue penetration, increase imaging sensitivity, and facilitate detection under low signal conditions. It also exhibits good stability and biocompatibility, supporting lesion imaging and intraoperative navigation applications.
Owner:SHENZHEN UNIV

Medical device, image processing method, computer program, and computer program product

This medical device comprises: a three-dimensional image data acquisition unit that acquires three-dimensional image data of a target blood vessel obtained by imaging the target blood vessel with a tomographic imaging device and first orientation information for specifying the orientation of the target blood vessel; a two-dimensional image data acquisition unit that acquires two-dimensional image data of the target blood vessel captured by an X-ray imaging device; an estimation unit that estimates second orientation information for specifying the orientation of the target blood vessel in the X-ray imaging device; and a generation unit that uses the first orientation information and the second orientation information to generate, from the three-dimensional image data, a display image in which the direction of the displayed target blood vessel is corrected, generates a two-dimensional image of the target blood vessel from the two-dimensional image data, and generates a superimposed image in which the target blood vessel displayed in the display image and the target blood vessel displayed in the two-dimensional image are superimposed.
Owner:ASAHI INTECC CO LTD

Intelligent PICC catheter and positioning system for tumor chemotherapy

This invention discloses an intelligent PICC catheter and positioning system for tumor chemotherapy, belonging to the field of biomedical engineering technology. This invention addresses the problem of inaccurate puncture due to the inherent subjectivity in puncture point selection in existing technologies. By assessing the importance of vascular imaging features and blood flow parameters, it can identify the features most influential on predicting puncture results, thereby reducing model complexity and improving model efficiency and generalization ability. Furthermore, by weighting the input data according to feature importance, the random forest model focuses more on important features, thus improving the accuracy and reliability of model predictions. Through the collaborative work of multiple modules, the positioning system is more accurate and efficient in recommending the optimal puncture point, effectively improving the puncture success rate, reducing the risk of complications, providing strong decision support for medical staff, and enhancing the patient's treatment experience and safety.
Owner:SECOND MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL

System and method for wound imaging

A device for characterizing a wound of an individual. The device includes a non- infrared-filtered imaging camera operable to capture images using visible and near infrared (NIR) wavelengths; an illumination source having one or more red / green sources and one or more NIR sources, wherein the one or more red / green sources are addressable independently from the one or more NIR sources; a controller in electronic communication with the imaging camera and the illumination source, the controller configured to: selectively activate the one or more red / green sources or the one or more NIR sources to illuminate the wound; capture at least one image of the wound illuminated by the activated sources; process the at least one captured image to provide one or more of oxygenation, pulsation, vascular imaging, and photoplethysmography information of the wound.
Owner:THE RES FOUNDATION FOR THE STATE UNIV OF NEW YORK

Identification method and device, computer device and storage medium

The application relates to an identification method and device, computer equipment and a storage medium. The method comprises the following steps: obtaining a blood vessel image of an eye to be examined, the blood vessel image being generated by optical coherence tomography blood vessel imaging; obtaining statistical features of a macular region in the blood vessel image; and identifying a non-perfusion region in the blood vessel image based on the statistical features. The method can effectively improve the flexibility of identifying the non-perfusion region.
Owner:SVISION IMAGING LTD

Method and device for generating a vessel imaging sequence

A vessel imaging sequence including plurality of vessel imaging frames and a corresponding ECG signal are generated by encoding, using a first encoder, an input vessel imaging sequence to generate a plurality of vessel latent space vectors, each vessel latent space vector corresponding to an input vessel imaging frame of the input vessel imaging sequence, encoding, using a second encoder, an input ECG signal to generate a plurality of ECG latent space vectors, decoding, using a first decoder, the plurality of vessel latent space vectors and the plurality of ECG latent space vectors to generate the vessel imaging sequence and decoding, using a second decoder, the vessel latent space vector and the ECG latent space vector to generate the ECG signal.
Owner:SIEMENS HEALTHINEERS AG

Computer method to optimize contrast-agent volume and injection force for vascular imaging

Systems and methods described herein relate to developing a virtual anatomical model of a coronary artery with specific conditions and related fluid properties, such as the velocity and viscosity of selected fluid, to provide accurate parameters for an intravascular imaging procedure. The resulting parameters may relate to the contrast agent volume, time for pullback of intravascular tool, and contrast agent injection force. The models may be patient specific, based on characteristics of a patient's artery. The systems and methods may be utilized for PCI planning, vascular device design and process optimization.
Owner:LIGHTLAB IMAGING LLC

Multi-line endoscopic OCT anti-interference microvascular imaging algorithm and imaging system

The present invention discloses a multi-line endoscopic OCT anti-interference microvascular imaging algorithm and imaging system. The algorithm includes utilizing a constructed multi-line endoscopic OCT imaging system for data acquisition; processing the data acquired in the current frame, calculating the spectrum information of the OCT structural imaging, and generating an OCT structural image; extracting and calculating blood flow information from the OCT structural image to generate a blood flow image; normalizing the blood flow image, color-labeling the normalized blood flow information, and superimposing the labeled blood flow information with a structural diagram; projecting the superimposed blood flow information structural diagram with principal component information to generate a vascular projection image; and performing three-dimensional spatial coordinate conversion on the projected information to convert it into three-dimensional spatial information with a tubular structure. The present application can utilize data acquired in a single frame for spectrum and structural analysis to obtain a blood flow image, overcome probe and tissue jitter, and has a simple structure that can effectively extract endoscopic microvascular imaging information.
Owner:HORIMED TECH CO LTD

Intravascular ultrasound catheter, vascular ultrasound detection system and control method

The application relates to an intravascular ultrasound catheter, a blood vessel ultrasound detection system and a control method. The intravascular ultrasound catheter comprises a tube body, a liquid injection port arranged at the proximal end of the tube body, and a liquid outlet arranged at the distal end of the tube body; a detection assembly comprising a transmission shaft, a first detection device and a second detection device, the first detection device and the second detection device being arranged at the distal end of the transmission shaft respectively, the second detection device being located on the proximal end side of the first detection device, the first detection device being an ultrasonic transducer, the transmission shaft being located in the tube body and capable of rotating relative to the tube body and moving along the axial direction of the tube body; wherein the first detection device is used for detecting a blood vessel, and the second detection device is used for detecting bubbles in the tube body. The scheme provided by the application can eliminate the influence of bubbles on blood vessel imaging during detection, and reduce the operation time and risk.
Owner:SHENZHEN INSIGHT MED CO LTD

Method, device, equipment and storage medium for evaluating the anchoring degree of vascular stent

The present invention discloses a method, device, equipment and storage medium for evaluating the anchoring degree of a vascular stent. By establishing a mapping relationship between the radial support force of the vascular stent and the radius of the vascular stent, an anchoring force index for evaluating the anchoring degree of the vascular stent is defined. Then, vascular imaging data is processed to generate a three-dimensional vascular model. In combination with the anchoring force index, a virtual implantation process of the vascular stent is performed on a computer. The anchoring force index of the vascular stent at different positions within the blood vessel is calculated and updated in real time according to the actual deployment degree of the vascular stent. Finally, clinical follow-up data after the vascular stent implantation is collected, and key characteristic parameters are extracted in combination with the anchoring force index. The trained vascular stent anchoring degree evaluation model is obtained using a machine learning model for training to evaluate the anchoring degree of the vascular stent. The anchoring force index proposed by the present invention from a mechanical perspective can more accurately evaluate the anchoring degree of the vascular stent.
Owner:HANGZHOU ARTERYFLOW TECH CO LTD +1

NIR-II region fluorescent probe suitable for intrathecal injection, preparation method of NIR-II region fluorescent probe and application of NIR-II region fluorescent probe in cerebrovascular imaging

The invention discloses an NIR-II region fluorescent probe suitable for intrathecal injection, a preparation method of the NIR-II region fluorescent probe and application of the NIR-II region fluorescent probe in cerebrovascular imaging, and belongs to the technical field of probe preparation. The problem of low resolution of current cerebrovascular imaging is solved. The rare earth nano fluorescent material is prepared into the NIR-II region fluorescent probe, delivery of large-size fluorescent imaging particles is achieved through intrathecal injection, and then cerebral vascular imaging is achieved. According to the rare earth nano fluorescent material, NaErF4: x% Ce serves as a fluorescence emission core, NaYF4: y% Yb serves as a fluorescence emission middle layer, NaYF4 serves as a fluorescence emission shell layer, through Er < 3 + > ion self-sensitization, under 808 nm excitation, an NIR-II region fluorescence emission peak of 1525 nm is achieved, NaYF4 serves as an inert shell layer, the luminous intensity of the fluorescent material is further improved, and NIR-II region high-resolution fluorescence imaging of mouse cerebral vessels is achieved in combination with intrathecal injection.
Owner:CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES

Adaptive infrared blood vessel imaging enhancement method and device based on image entropy feedback

PendingCN122289090APattern recognitionBiology
This application provides an adaptive infrared vascular imaging enhancement method and apparatus based on image entropy feedback. It achieves precise adaptive adjustment of infrared emission power through local information entropy calculation and a proportional-integral-differential controller. An enhancement mechanism is constructed, combining multi-scale Gaussian smoothing and Hessian matrix eigenvalue analysis to establish a reliable vascular response extraction strategy. Structural analysis optimization is introduced, iteratively refining skeleton extraction and cross-point calculation to ensure continuous improvement in vascular cross-point localization. This method effectively addresses the shortcomings of traditional techniques in exposure adaptation, vascular enhancement, and topology analysis, providing technical support for infrared vascular imaging-assisted diagnosis.
Owner:PLASTIC SURGERY HOSPITAL CHINESE ACADEMY OF MEDICAL SCIENCES +1

Optic nerve analysis method and system based on optical coherence tomography angiography

The present invention relates to a optic nerve analysis method and system based on optical coherence tomography angiography, the method comprising the following steps: acquiring an image of the nerve layer surrounding the optic nerve using optical coherence tomography angiography technology; identifying the position of a red signal representing a blood vessel in the acquired nerve layer image; and measuring the height of the red signal position and the thickness of the nerve layer on the left and right adjacent sides of the red signal position. The present invention differs from existing retinal nerve layer thickness and thickness analysis using neural analysis packages in that, for patients with retinal thinning caused by high myopia, not only is thickness analysis used to determine whether the retina is atrophied, but changes in the vascular structure can also be used to determine whether true nerve layer atrophy or overall retinal atrophy caused by high myopia. Furthermore, the present invention has lower requirements for image quality and patient cooperation, making analysis easier.
Owner:SHENZHEN EYE HOSPITAL

Dynamic vascular imaging method and apparatus based on CT perfusion images

The present invention relates to the field of image processing, and particularly relates to a dynamic vascular imaging method and apparatus based on CT perfusion images. The method comprises: acquiring a plurality of perfusion images obtained by means of performing CT scanning on each target layer in a region of interest, and determining an image set on the basis of the plurality of perfusion images; according to a scanning time sequence, defining every two adjacent images in the image set to be an image group, defining the scanning time of a second image in each image group to be later than that of a first image, and subtracting the first image from the second image in each image group, so as to obtain a corresponding local vascular image; acquiring all the local vascular images corresponding to all the target layers; obtaining three-dimensional vascular point cloud data on the basis of all the local vascular images; and inputting the three-dimensional vascular point cloud data into a preset deep learning model, so as to obtain a target vascular image. In the present invention, perfusion images are used to directly track blood vessels and reconstruct the blood vessels, thereby quickly obtaining a complete vascular image.
Owner:SHANGHAI SIXTH PEOPLES HOSPITAL