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Novel biofiber hemostatic material and preparing method thereof

A bio-fiber and hemostatic material technology, applied in the field of biomedical hemostatic materials, can solve the problems of unsatisfactory hemostatic effect, insufficient hemostasis speed, limited wide application, etc., and achieve the effects of easy swelling, easy cleaning, and reduced residues

Inactive Publication Date: 2016-06-08
GUANGXI XINYE BIOLOGICAL TECH +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the hemostatic effect of these current technologies is not ideal, and the hemostatic speed is not fast enough, which limits its wide application in clinical practice.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A novel biological fiber hemostatic material is composed of the following raw materials in weight percentage:

[0037] Hyaluronic Acid 50%

[0038] Puffball spore powder 50%.

[0039] The hyaluronic acid is a mixture of powders with a particle diameter of 2 nanometers and powders with a particle diameter of 500 microns at a mass ratio of 1:5.

[0040] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 110 degrees Celsius, crushing and passing through a sieve of more than 100 mesh.

[0041] A novel biological fiber hemostatic material is obtained by mixing the above-mentioned hyaluronic acid and puffball spore powder.

Embodiment 2

[0043] A novel biological fiber hemostatic material is composed of the following raw materials in weight percentage:

[0044] Hyaluronic Acid 60%

[0045] Puffball spore powder 40%.

[0046] The hyaluronic acid is a pharmaceutical grade powder with an average molecular weight of 800 Daltons.

[0047] The hyaluronic acid is a mixture of powders with a particle size of 200 nanometers and powders with a particle size of 50 microns in a mass ratio of 1:3.

[0048] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 120 degrees Celsius, and passing through a sieve with a mesh size of 100 or more after crushing.

[0049] A new type of biological fiber hemostatic material is obtained by mixing hyaluronic acid and puffball spore powder.

[0050] After mixing hyaluronic acid and puffball spore powder evenly, continue ultrasonic vibration for 2 hours.

Embodiment 3

[0052] A novel biological fiber hemostatic material is composed of the following raw materials in weight percentage:

[0053] Hyaluronic Acid 70%

[0054] Puffball spore powder 30%.

[0055] The hyaluronic acid is a pharmaceutical grade powder with an average molecular weight of 1000 Daltons.

[0056] The hyaluronic acid is a mixture of powders with a particle size of 100 nanometers and powders with a particle size of 200 microns in a mass ratio of 3:7.

[0057] The puffball spore powder is the puffball spore powder obtained by peeling off the outer skin of the puffball, digging out the contents and sieving the spores, drying the spores at 130 degrees Celsius, and passing through a sieve with a mesh size of 100 or more after crushing.

[0058] A new type of biological fiber hemostatic material is obtained by mixing hyaluronic acid and puffball spore powder.

[0059] After mixing hyaluronic acid and puffball spore powder evenly, continue ultrasonic vibration for 5 hours.

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PUM

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Abstract

The invention relates to biological medicine hemostatic materials, in particular to a novel biofiber hemostatic material and a preparing method thereof. The novel biofiber hemostatic material is composed of hyaluronic acid and puffball conidial powder. Hyaluronic acid can absorb water in blood instantly to form hydrogel, so that errhysis is stopped; a large number of micro porous fibers are stored in puffball conidial powder and can absorb water in blood quickly and block a blood vessel rupture and stop blood capillary errhysis mechanically; a physical barrier is formed by the two substances to isolate a wound so as to achieve anti-adhesion and instant hemostasis. The novel biofiber hemostatic material is used for hemostasis of errhysis of various wounds and fresh tissue wound surfaces, small vessel hemorrhage and hemorrhage areas, and can prevent adhesion.

Description

technical field [0001] The invention relates to the technical field of biomedical hemostatic materials, in particular to a novel biological fiber hemostatic material and a preparation method thereof. Background technique [0002] Hemostasis is an important link in the operation of various departments in the hospital, and plays a considerable role in the success of the operation and the safety of the patient. The normal hemostasis mechanism mainly includes three aspects: the contraction of small blood vessels, the activation of platelets and the activation of the coagulation system. Among them, the contraction of small blood vessels is the earliest response to hemostasis after trauma. After the blood vessels are damaged, the smooth muscles of the blood vessels constrict the blood vessels and slow down the blood flow through axon reflex, which is beneficial to blood coagulation and hemostasis. Platelets have the physiological function of adhering to the surface of wounds and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/08A61L24/00
CPCA61L24/08A61L24/0015A61L24/0036A61L2300/30A61L2300/404A61L2300/412A61L2300/418
Inventor 梁奕福
Owner GUANGXI XINYE BIOLOGICAL TECH
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