Composition capable of increasing high-density lipoprotein and preventing and treating atherosclerosis and preparing method and application thereof

An atherosclerosis and high-density lipoprotein technology, applied in the field of medicine, can solve the problem of high incidence of adverse reactions, and achieve the effects of avoiding adverse reactions, no toxic side effects, and increasing high-density lipoprotein

Inactive Publication Date: 2016-07-06
DELI WEI BEIJING BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] (3) Clofibrate esters, such as clofibrate, fenofibrate, bezafibrate, etc., the incidence of adverse reactions of such antihyperlipidemic drugs is relatively high (5% to 10%)

Method used

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  • Composition capable of increasing high-density lipoprotein and preventing and treating atherosclerosis and preparing method and application thereof
  • Composition capable of increasing high-density lipoprotein and preventing and treating atherosclerosis and preparing method and application thereof
  • Composition capable of increasing high-density lipoprotein and preventing and treating atherosclerosis and preparing method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A composition that can increase high-density lipoprotein and prevent and treat atherosclerosis. The components and dosage are shown in Table 1:

[0038] Table 1 composition formula (weight part)

[0039]

[0040]

[0041] Preparation:

[0042] (1) Pretreatment of each component in the composition: each component of the prescription amount is ultrafinely pulverized at a low temperature at -20°C, and the particle size of the material reaches 1000-1200 mesh.

[0043] (2) Preparation of γ-aminobutyric acid natto red yeast rice tablets: Weigh the pretreated γ-aminobutyric acid, nattokinase and red yeast rice flour, add appropriate amount of starch, D-mannose Alcohol and magnesium stearate are mixed to obtain gamma-aminobutyric acid natto red yeast rice tablets by powder direct compression method, with a tablet weight of 0.7g, and auxiliary materials account for 22% of the tablet weight.

[0044] (3) The remaining components in the composition are fully mixed accordin...

Embodiment 2

[0047] A composition that can increase high-density lipoprotein and prevent and treat atherosclerosis. The components and dosage are shown in Table 2:

[0048] Table 2 composition formulation (parts by weight)

[0049]

[0050]

[0051] Preparation:

[0052] (1) Pretreatment of each component in the composition: each component of the prescription amount is ultrafinely pulverized at a low temperature at -20°C, and the particle size of the material reaches 1000-1200 mesh.

[0053] (2) Preparation of γ-aminobutyric acid natto red yeast rice tablets: Weigh the pretreated γ-aminobutyric acid, nattokinase and red yeast rice flour, add appropriate amount of starch, D-mannose Alcohol and magnesium stearate are mixed to obtain gamma-aminobutyric acid natto red yeast rice tablets by powder direct compression method, with a tablet weight of 0.7g, and auxiliary materials account for 22% of the tablet weight.

[0054] (3) According to the prescription, the remaining components in t...

Embodiment 3

[0057] A composition that can increase high-density lipoprotein and prevent and treat atherosclerosis. The components and dosage are shown in Table 3:

[0058] Table 3 composition formula (weight part)

[0059] components

[0060] The preparation method and use method are the same as those in Example 1.

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Abstract

The invention relates to the field of medicine, in particular to a composition capable of increasing high-density lipoprotein and preventing and treating atherosclerosis. The composition is prepared from, by weight, 200-500 parts of nattokinase, 50-150 parts of red yeast rice powder, 60-180 parts of gamma-aminobutyric acid, 100-300 parts of taurine, 50-150 parts of ascorbic acid, 250-750 parts of haematococcus pluvialis, 100-3000 parts of blueberry powder, 0-3000 parts of whey protein powder, 10-300 parts of dietary fiber and 0.01-0.5 part of xanthophyll. The invention further provides a preparing method and application of the composition. All the components in the composition are affinal drug and diet substances and free of toxic and side effects, and various adverse effects of an existing anti-hyperlipidemia drug are avoided; the composition is convenient to take, the problem is solved at the cell level, and high-density lipoprotein is increased.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a composition capable of increasing high-density lipoprotein and preventing and treating atherosclerosis, as well as its preparation method and application. Background technique [0002] High-density lipoprotein is one of the main lipoproteins in the human body and the basic substance of blood lipid metabolism. It has the functions of removing excess blood fat in blood vessels, removing blood scale, and cleaning blood vessels. Normal blood lipid metabolism means that the amount of high-density lipoprotein is proportional to low-density lipoprotein or triglyceride. The amount of high-density lipoprotein not only determines whether the blood lipid metabolism in the blood is balanced, but also plays a role in the elimination or lightening of arterial Important role in hardened plaque. Low high-density lipoprotein is mostly caused by bad living habits. Therefore, patients should start with a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61P3/06A61P9/10A61K36/899A61K36/062A61K31/197A61K31/185A61K31/375A61K36/05A61K36/45A61K31/047A61K38/02
CPCA61K38/482A61K31/047A61K31/185A61K31/197A61K31/375A61K36/05A61K36/062A61K36/45A61K36/899A61K38/02A61K2236/19C12Y304/21062A61K2300/00
Inventor 邓吉林吴莹程晓波吴宝珍邓红玲
Owner DELI WEI BEIJING BIOLOGICAL TECH
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