Traditional Chinese medicine oral liquid with liver protecting effect and preparation method thereof

A technology of traditional Chinese medicine oral liquid and action, applied in the direction of medical preparations containing active ingredients, medical formulas, drug combinations, etc., can solve the problems of great damage to liver and kidney function, damage to liver function, and treatment dilemmas, and achieve the reduction of Mycobacterium tuberculosis Variation, avoidance of discontinuation, fast-acting effect

Inactive Publication Date: 2016-08-03
衣明春
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, Western medicine is mainly used to treat pulmonary tuberculosis clinically, such as rifapentine, rifampicin, isoniazid and other drugs, but these drugs are chemotherapy drugs, which are harmful to various organs of the human body while killing tuberculosis bacteria. It is also extremely harmful, especially to the liver and kidney functions. During the treatment of tuberculosis patients, it is often necessary to stop the treatment of tuberculosis drugs and turn to the liver due to impaired liver function. Once tuberculosis drugs are used Stopping it will allow Mycobacterium tuberculosis to mutate and become resistant to existing drugs. Once drug resistance develops, there may be no cure, and the consequences will be disastrous. If you continue to use the drug, it will continue to damage the liver function, making the treatment a dilemma , the existing liver-protecting drugs against tuberculosis drugs have little effect on liver function damage, therefore, it is of great significance to find a good drug for protecting the liver against tuberculosis drugs

Method used

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  • Traditional Chinese medicine oral liquid with liver protecting effect and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Prepare oral liquid of the present invention according to the following steps:

[0022] Step 1: Weigh 120g wolfberry, 150g salvia miltiorrhiza, 150g white peony, 130g chuanxiong, 200g licorice, 120g chrysanthemum, 120g notoginseng, 120g eucommia, 70g maca, 150g cistanche, 10-200g sealwort, 130g cassia twig, and schisandra 80g, add water with 4 times the mass of dry herbs and soak for 1 hour, then boil with high fire until half an hour after boiling, filter, take the filtrate for the first time, add 3 times the water to the residue and boil for 10 minutes after boiling, filter, take the second time Filtrate, combined twice filtrate, standby;

[0023] Step 2: Combine the filtrate obtained in step: 1 at a temperature of 50°C and concentrate under reduced pressure to a ointment with a relative density of 1.21 when the temperature is 50°C. Take 10g of the ointment, add 0.5g of sodium alginate, 1.5g of xylose, 88g of water was stirred evenly, filtered, filled, and made into ...

Embodiment 2

[0025] Prepare oral liquid of the present invention according to the following steps:

[0026] Step 1: Weigh 100g wolfberry, 100g salvia miltiorrhiza, 200g white peony, 150g chuanxiong, 250g licorice, 100g chrysanthemum, 100g notoginseng, 100g eucommia, 50g maca, 100g cistanche, 200g sealwort, 150g cassia twig, 100g schisandra, according to the prescription amount, Add 5 times the quality of dry medicinal materials in water and soak for 1.5 hours, then boil with high fire until half an hour after boiling, filter, take the first filtrate, add 4 times the water to the filter residue and boil for 10 minutes after boiling, filter, and take the second filtrate, Merge the two filtrates for subsequent use;

[0027] Step 2: Combine the filtrate obtained in step: 1 at a temperature of 50° C. and concentrate under reduced pressure to an ointment with a relative density of 1.27 when the temperature is 50° C., add conventional pharmaceutical excipients for the oral liquid, and make the or...

Embodiment 3

[0029] Prepare oral liquid of the present invention according to the following steps:

[0030] Step 1: Weigh 150g wolfberry, 200g salvia miltiorrhiza, 200g white peony, 150g chuanxiong, 150g licorice, 100g chrysanthemum, 100g notoginseng, 100g eucommia, 100g maca, 200g cistanche, 100g sealwort, 100g cassia twig, 50g schisandra according to the prescription amount, Add 6 times the quality of dry medicinal materials in water and soak for 2 hours, then boil with high fire until half an hour after boiling, filter, take the first filtrate, add 4 times the water to the filter residue and boil for 10 minutes after boiling, filter, take the second filtrate, Merge the two filtrates for subsequent use;

[0031] Step 2: Combine the filtrate obtained in step: 1 at a temperature of 50° C. and concentrate under reduced pressure to an ointment with a relative density of 1.24 at a temperature of 50° C., add conventional pharmaceutical excipients for the oral liquid, and make an oral liquid ac...

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Abstract

The invention discloses a traditional Chinese medicine oral liquid with the liver protecting effect and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine oral liquid is prepared from, by weight, 10-15 parts of barbary wolfberry fruit, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of radix paeoniae alba, 10-15 parts of chuanxiong rhizomes, 15-25 parts of licorice roots, 10-15 parts of chrysanthemum flowers, 10-15 parts of panax notoginseng, 10-15 parts of cortex eucommiae, 5-10 parts of maca, 10-20 parts of herba cistanche, 10-20 parts of rhizoma polygonati, 10-15 parts of cassia twigs and 5-10 parts of Chinese magnoliavine fruit. The traditional Chinese medicine oral liquid can effectively protect the liver and prevent damage of antituberculous drugs to the liver.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine oral liquid with liver-protecting effect and a preparation method thereof, which are used for protecting liver function from being damaged by western medicine antibiotic tuberculosis drugs during the treatment of pulmonary tuberculosis. Background technique [0002] Tuberculosis, also known as tuberculosis and "white plague", is an ancient infectious disease, and tuberculosis has existed since human beings existed. In history, it was widely popular all over the world and was once the main killer against human beings, taking hundreds of millions of lives. Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis infection. Mycobacterium tuberculosis may invade various organs of the human body, but mainly invades the lungs, which is called pulmonary tuberculosis. Tuberculosis can occur throughout the year...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P1/16
CPCA61K36/815A61K9/0095A61K36/236A61K36/258A61K36/287A61K36/31A61K36/46A61K36/484A61K36/537A61K36/54A61K36/57A61K36/64A61K36/65A61K36/71A61K36/79A61K36/8969A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 衣明春
Owner 衣明春
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