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Oral medical ice for preventing and treating oral ulcer and infection

A technology for oral ulcers and strong fragrant cuckoo, which is applied in the field of adjuvant therapy drugs, can solve problems such as the repair of rare oral mucosa, and achieve the effects of shortening healing time, reducing pain, and reducing exudation.

Inactive Publication Date: 2016-08-10
杨力
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, the commonly used drugs for the prevention and treatment of oral ulcers and infections are mainly anti-infective mouthwash drugs with different components, but there are few drugs aimed at promoting the repair of oral mucosa

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Net selection of eight flavors of medicinal materials: bitter gourd, rhododendron, honeysuckle, forsythia, Ophiopogon japonicus, ginseng, corydalis, and licorice, dried at a temperature not higher than 50°C, and then 60 parts of bitter gourd and 50 parts of rhododendron were taken 60 parts of honeysuckle, 20 parts of forsythia, 30 parts of Ophiopogon japonicus, 30 parts of Yuanshen, 10 parts of Corydalis 10 parts, 10 parts of licorice plus 10 times of water, decoct for 1 hour, filter out the liquid medicine, sterilize and cool in the sterilization room Finally, add 70ug of granulocyte-macrophage colony-stimulating factor (GM-CSF), 60mg of calcium folinate (CF), 350mg of lidocaine hydrochloride and 450mg of vitamin C to each 100 ml of cooling liquid, and put the cooling liquid containing the above ingredients into In a sterile container, freeze into ice.

[0029] How to use: Take the above-mentioned appropriate amount of mouth ice every 2 hours from morning to sleep, put...

Embodiment 2

[0031] Net selection of eight flavors of medicinal materials: bitter gourd, rhododendron, honeysuckle, forsythia, Ophiopogon japonicus, ginseng, corydalis, and licorice, dried at a temperature not higher than 50°C, and then 50 parts of bitter gourd and 40 parts of rhododendron were taken 40 parts of honeysuckle, 10 parts of forsythia, 10 parts of Radix Ophiopogon japonicus, 15 parts of Yuanshen, 5 parts of Corydalis Corydalis, 5 parts of licorice plus 10 times of water, decocted for 1 hour, filtered out the liquid medicine, sterilized and cooled in the sterilization room Finally, add granule-macrophage colony-stimulating factor (GM-CSF) 60ug, calcium folinate (CF) 40mg, lidocaine hydrochloride 300mg and vitamin C 400mg into each 100 ml of cooling liquid, and put the cooling liquid containing the above ingredients into In a sterile container, freeze into ice.

[0032] Using method is as embodiment 1.

Embodiment 3

[0034] Net selection of eight flavors of medicinal materials: bitter gourd, rhododendron, honeysuckle, forsythia, Ophiopogon japonicus, ginseng, corydalis, and licorice, dried at a temperature not higher than 50°C, and then 80 parts of bitter gourd and 60 parts of rhododendron were taken 70 parts of honeysuckle, 40 parts of forsythia, 45 parts of Ophiopogon japonicus, 40 parts of Yuanshen, 20 parts of Corydalis Corydalis, 15 parts of licorice, add 10 times of water to decoct for 1 hour, filter out the liquid medicine, sterilize and cool in the sterilization room Finally, 80ug of granulocyte-macrophage colony-stimulating factor (GM-CSF), 80mg of calcium folinate (CF), 400mg of lidocaine hydrochloride and 500mg of vitamin C were added to each 100 ml cooling solution. Put the cooling liquid containing the above ingredients into a sterile container and freeze it into ice.

[0035] Using method is as embodiment 1.

[0036] Below in conjunction with clinical data and typical cases th...

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Abstract

The invention discloses oral medical ice for preventing and treating oral ulcer and infection. The oral medical ice comprises, by weight, 50-80 parts of Momorica dioica, 40-60 parts of Flos Rhododendri Anthopgonoidi, 40-70 parts of Flos Lonicerae, 10-40 parts of Fructus Forsythiae, 10-45 parts of Radix Ophiopogonis, 15-40 parts of Radix Scrophulariae, 5-20 parts of Rhizoma Corydalis, 5-15 parts of Radix Glycyrrhizae, granulocyte-macrophage colony stimulating factor, calcium folinate, lidocaine hydrochloride and vitamin C. Per 100ml of the oral medical ice contains 60-80microgram of the granulocyte-macrophage colony stimulating factor, 40-80mg of the calcium folinate, 300-400mg of the lidocaine hydrochloride and 400-500mg of the vitamin C. The oral medical ice has the advantages that pains can be alleviated for patients, vasoconstriction of oral mucosa is realized to reduce exudation, and accordingly oral hygiene is benefited; oral ulcer healing time can be shortened, a disease course is shortened, toxic and side effects are avoided, and high compliance is achieved; easiness in material acquisition, low cost and promising application prospect are realized.

Description

technical field [0001] The invention belongs to the technical field of auxiliary therapeutic drugs, relates to mouth ice, in particular to mouth ice for preventing and treating oral ulcer and infection. Background technique [0002] Oral ulcers, also known as "oral sores", are superficial ulcers that occur on the oral mucosa. The size can range from rice grains to soybeans, and they are round or oval. The ulcer surface is concave and surrounded by congestion. Ulcers have the characteristics of periodicity, recurrence and self-limitation, and are prone to occur on the lips, cheeks, and tongue margins. The etiology and pathogenic mechanism are still unclear. The inducement may be local trauma, mental stress, food, drugs, changes in hormone levels, and vitamin or trace element deficiency. It mostly occurs in patients after maxillofacial surgery and chemotherapy. [0003] After maxillofacial surgery, patients will experience pain and swelling in the maxillofacial region, which ...

Claims

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Application Information

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IPC IPC(8): A61K38/19A61P1/02A61K36/8968A61K31/167A61K31/375A61K31/519
CPCA61K36/428A61K9/0056A61K31/167A61K31/375A61K31/519A61K36/355A61K36/45A61K36/484A61K36/634A61K36/66A61K36/808A61K36/8968A61K38/19A61K2236/331A61K2300/00
Inventor 杨力刘亭娜
Owner 杨力
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