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Ginseng tablet capable of strengthening spleen and preparation method thereof

A technology of ginseng invigorating spleen tablets and ginseng, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem of affecting drug absorption, unscientific, and disintegration time of ginseng invigorating spleen tablets long wait question

Inactive Publication Date: 2016-08-17
韩志强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the extraction process is unreasonable and unscientific, it will inevitably cause damage and loss of active ingredients, thereby affecting the quality and curative effect of the preparation
In addition, the disintegration time of existing Ginseng Jianpi Tablets is relatively long, especially after long-term storage, there are phenomena that exceed the pharmacopoeia standards. Too long disintegration time will seriously affect the absorption of drugs
[0004] With the continuous improvement of clinical requirements on the quality and effect of drugs and the continuous development of pharmaceutical technology, this technology can no longer meet the current needs. There is an urgent need for a preparation technology with more complete extraction of active ingredients and higher content to better play the role of ginseng. Medicinal Value of Classical Prescriptions of Jianpi Tablets

Method used

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  • Ginseng tablet capable of strengthening spleen and preparation method thereof
  • Ginseng tablet capable of strengthening spleen and preparation method thereof
  • Ginseng tablet capable of strengthening spleen and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0110]

[0111]

[0112] The preparation method is:

[0113] Wash ginseng, Atractylodes macrocephala, licorice, lotus seeds, white lentils, Gorgon fruit and angelica respectively, soak them in 3 times the amount of water for 10 hours, remove them, and dry the water, keep the surface of Chinese medicinal materials dry, and freeze them at -20°C for 2 hours Carry out ultrafine pulverization in the environment of -6 DEG C afterward to obtain superfine powder; After superfine pulverization, 90%-95% of the micropowder particle size is 4-6 micron; Soak yam with 8 times the amount of water for 30 minutes, Add 12g of compound enzyme, the compound enzyme is 3:1 α-amylase and protein phosphatase, first carry out enzymolysis at 40°C for 30 minutes, then decoct, decoct for the first time for 3 hours, filter to obtain the filtrate , decoct the dregs with 6 times the amount of water for 2 hours, filter to obtain the filtrate, combine the two filtrates, filter, concentrate the filtrate ...

Embodiment 2

[0115]

[0116]

[0117] Wash ginseng, Atractylodes macrocephala, licorice, lotus seeds, white lentils, Gorgon fruit and angelica respectively, soak them in 3 times the amount of water for 10 hours, remove them, and dry the water, keep the surface of Chinese medicinal materials dry, and freeze them at -20°C for 2 hours Carry out ultrafine pulverization in the environment of -6 DEG C afterward to obtain superfine powder; After superfine pulverization, 90%-95% of the micropowder particle size is 4-6 micron; Soak yam with 8 times the amount of water for 30 minutes, Add 12g of compound enzyme, the compound enzyme is 3:1 α-amylase and protein phosphatase, first carry out enzymolysis at 40°C for 30 minutes, then decoct, decoct for 3 hours for the first time, filter to obtain the filtrate , decoct the dregs with 6 times the amount of water for 2 hours, filter to obtain the filtrate, combine the two filtrates, filter, concentrate the filtrate to 80°C, measure the relative density...

Embodiment 3

[0119]

[0120]

[0121] Wash ginseng, Atractylodes macrocephala, licorice, lotus seeds, white lentils, Gorgon fruit and angelica respectively, soak them in 3 times the amount of water for 10 hours, remove them, and dry the water, keep the surface of Chinese medicinal materials dry, and freeze them at -20°C for 2 hours Carry out ultrafine pulverization in the environment of -6 DEG C afterward to obtain superfine powder; After superfine pulverization, 90%-95% of the micropowder particle size is 4-6 micron; Soak yam with 8 times the amount of water for 30 minutes, Add 12g of compound enzyme, the compound enzyme is 3:1 α-amylase and protein phosphatase, first carry out enzymolysis at 40°C for 30 minutes, then decoct, decoct for the first time for 3 hours, filter to obtain the filtrate , decoct the dregs with 6 times the amount of water for 2 hours, filter to obtain the filtrate, combine the two filtrates, filter, concentrate the filtrate to 80°C, measure the relative density...

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Abstract

The invention discloses a ginseng tablet capable of strengthening the spleen and a preparation method thereof. The ginseng tablet capable of strengthening the spleen is prepared from ginseng, white atractylodes rhizome, licorice, Chinese yam, lotus seeds, semen dolichoris album, costus roots, alpinia katsumadai hayata, dried orange peel, green tangerine peel, medicated leaven, rice sprouts, hawthorn fruits, euryale seeds, coix seeds, angelica and bitter orange. The preparation method of the ginseng tablet capable of strengthening the spleen comprises the following steps: carrying out ultra-micro grinding on the ginseng, white atractylodes rhizome, licorice, lotus seeds, semen dolichoris album, euryale seeds and angelica; carrying enzymolysis on the Chinese yam, medicated leaven and coix seeds by using complex enzymes, and then carrying out decocting; and carrying out supercritical extraction on the rest of raw medicines. The ginseng tablet and the preparation method thereof have the advantages that a right amount of disintegrating agent is added in the improved process, and the tablet prepared after the disintegrating agent is added has short disintegration time; according to the process, effective ingredients are not damaged, more complete effective ingredients of the medicines can be extracted, the dissolution rate of drugs is high, the retention time of the drug effect is long, the bioavailability is high, and the stability is better; and according to the method, the extracts are purified, and the curative effect is obviously increased in comparison with the traditional process.

Description

technical field [0001] The invention relates to a pharmaceutical preparation in the field of medicine, in particular to a ginseng invigorating spleen tablet and a preparation method thereof. Background technique [0002] Ginseng Jianpi Tablets are listed in the Chinese Pharmacopoeia. It is prepared from ginseng, Atractylodes macrocephala, licorice, yam, lotus seeds, white lentils, woody fragrance, cardamom, tangerine peel, green peel, Liushenqu, grain buds, hawthorn, gorgon, coix seed, angelica and aurantium husk. , Appetizing and eliminating food, used for symptoms such as lack of food and loose stools, vomiting or diarrhea, fullness in the abdomen, weakness of limbs, and sallow complexion caused by spleen deficiency and dampness. [0003] At present, the preparation process of ginseng invigorating spleen tablets basically follows the traditional process method, crushing ginseng, Liushenqu, cardamom, and grain buds into fine powder, and decocting the rest of the raw materi...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61K9/28A61K47/32A61K47/04A61P1/14A61P1/08A61P1/12
CPCA61K36/9062A61K9/2009A61K9/2027A61K9/28A61K36/00A61K36/232A61K36/258A61K36/284A61K36/285A61K36/48A61K36/484A61K36/62A61K36/734A61K36/752A61K36/8945A61K36/899A61K36/8994A61K2236/15A61K2236/19A61K2236/331A61K2236/37A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 韩志强
Owner 韩志强
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