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Traditional Chinese medicine composition for treating premature ovarian failure of females and preparation method thereof

A technology of premature ovarian failure and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for treating women with liver-fire type leukorrhea, which can solve the problems that are not conducive to the condition and damage the health of patients, so as to reduce the curative effect, increase the cost, and have good safety Effect

Inactive Publication Date: 2016-09-21
杨高林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For physical therapy, there is also a limit, and it cannot be excessive. Excessiveness is not conducive to the condition and will damage the health of the patient.

Method used

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  • Traditional Chinese medicine composition for treating premature ovarian failure of females and preparation method thereof
  • Traditional Chinese medicine composition for treating premature ovarian failure of females and preparation method thereof
  • Traditional Chinese medicine composition for treating premature ovarian failure of females and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0065] The preparation steps of the pill for oral administration of the present invention are as follows: take 1500g of Radix Paeoniae Rubra, 1500g of Gallis Spatholobus, 1500g of Cornus officinalis, 1500g of Motherwort, 1500g of Bupleurum, 1500g of Comfrey, 1500g of Rehmannia glutinosa, 1500g of Ligustrum lucidum, 1500g of Eclipta chinensis, 1500g of Schisandra chinensis, Pot 1500g, Cuscuta 1500g, Epimedium 1500g, Danpi 1500g, Pueraria 1500g, Plantago 1500g, Anemarrhena 1500g, add water to soak for 30 minutes to 1 hour, heat and boil for 30 to 40 minutes, filter, and the filtrate is set aside; add water to the filter residue, Heating for the second time, boiling for 30 to 40 minutes, filtering, and the filtrate for later use; adding water to the filter residue, heating and boiling for the third time for 30 to 40 minutes, and filtering; combining the three filtrates together, heating and concentrating to a paste, drying in an oven, into fine powder, mixed with honey and kneaded...

Embodiment 3

[0081] 2.1. Tested substance: name: suppository of the present invention (prepared by the method of Example 3)

[0082] 2.2. Experimental animals: Grade 1 white rabbits with large ears, 10 females, weighing 2.1-2.3kg; provided by the Experimental Animal Center of the Department of Biology, Qingdao University School of Medicine;

[0083] 2.3. Test method:

[0084] 10 healthy rabbits with intact skin were selected, and the hair on both sides of the back and spine was cut off 24 hours before the test. The left and right areas of hair removal were about 4cm×4cm. During the test, take 0.2ml of the test substance and apply it on two layers of gauze of 2.5cm×2.5cm, apply it on one side of the depilated skin surface, cover it with oil paper, and fix it with adhesive tape. The skin on the other side was used as a blank control. After 4 hours of sealing, remove the cover, wash with warm water to remove the residual test substance, treat the skin reaction at the application site 1, 24 ...

Embodiment 4

[0092] Embodiment 4: skin allergy test result

[0093] Use the suppository of the present invention to carry out induction and excitation contact tests, and treat the test mice after 24 hours and 48 hours, and there is no phenomenon such as erythema and edema in the skin, and there is no difference with the negative control group. The results show that the suppository has close to zero skin reaction intensity, that is, no skin allergy.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating the premature ovarian failure of females. The traditional Chinese medicine composition is prepared from orally taken medicine including 10-20 parts of the root of common peony, 10-20 parts of suberect spatholobus stem, 10-20 parts of dogwood, 10-20 parts of motherwort herb, 10-20 parts of radix bupleuri, 10-20 parts of radices lithospermi, 10-20 parts of prepared rehmannia roots, 10-20 parts of glossy privet fruits, 10-20 parts of herba ecliptae, 10-20 parts of the fruit of Chinese magnoliavine, 10-20 parts of fructus rubi, 10-20 parts of the seed of Chinese dodder, 10-20 parts of herba epimedii, 10-20 parts of the root bark of the peony tree, 10-20 parts of the root of kudzu vine, 10-20 parts of semen plantaginis and 10-20 parts of rhizoma anemarrhenae, and external-use medicine including 10-20 parts of radix arnebiae seu lithospermi, 10-20 parts of radix sophorae flavescentis, 10-20 parts of fructus cnidii, 10-20 parts of rhizoma smilacis glabrae, 10-20 parts of common bletilla tubers, 10-20 parts of folium artemisiae argyi, 10-20 parts of common baphicacanthus rhizomes and roots, 10-20 parts of common selfheal fruit-spike, 10-20 parts of borneol and 10-20 parts of herb of regel eyebright. All the medicine materials are used together to achieve the effects of tonifying the kidney, nourishing yin, promoting blood circulation, nourishing food and dredging Chong meridians.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, in particular to a traditional Chinese medicine composition for treating women with liver-fire type leukorrhea and a preparation method thereof. Background technique [0002] Premature ovarian failure (POF) refers to the phenomenon of amenorrhea before the age of 40 caused by ovarian failure. It is characterized by primary or secondary amenorrhea accompanied by elevated blood gonadotropin levels and decreased estrogen levels, accompanied by a series of low estrogen symptoms such as hot flashes, hyperhidrosis, facial flushing, and low libido. The average natural menopausal age of women is 50-52 years old, and there are differences in the distribution of menopausal age among races and regions, but the absolute value is not much different. Coulam et al. summarized the natural amenorrhea of ​​1858 women, and the incidence of POF was 1% for those younger than 40 years...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K36/90A61K36/898A61P15/08A61K31/045
CPCA61K36/8964A61K31/045A61K36/195A61K36/233A61K36/234A61K36/28A61K36/282A61K36/296A61K36/30A61K36/315A61K36/39A61K36/40A61K36/486A61K36/488A61K36/489A61K36/533A61K36/536A61K36/57A61K36/638A61K36/65A61K36/68A61K36/704A61K36/71A61K36/73A61K36/79A61K36/80A61K36/804A61K36/896A61K36/898A61K36/90A61K2236/33A61K2236/331A61K2236/39A61K2300/00
Inventor 杨高林
Owner 杨高林
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