Preparation method for antimicrobial peptide formula for dental implant

A technology for dental implants and dental implants is applied in the field of preparation of antimicrobial peptide formulations, which can solve the problems of implant loosening and falling off, peripheral bone tissue defect and loss, etc., and achieves broad application prospects and high-efficiency sterilization effects.
CN106512091AInactive Publication Date: 2017-03-22DALIAN SANSHENG SCI & TECH DEV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
DALIAN SANSHENG SCI & TECH DEV
Publication Date
2017-03-22
Estimated Expiration
Not applicable · inactive patent
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Abstract

The invention discloses a preparation method for an antimicrobial peptide formula for a dental implant, especially for the dental implant with different layers of coatings. The coatings are arranged as molecular coatings which are formed and sequentially arrayed on the solid surface of the dental implant under the electrostatic attraction effect between positive ions and negative ions. Chitosan and hyaluronic acid coatings are made from the biological materials with excellent biological degradability and biocompatibility. Due to the existence of a surface chondroitin sulfate layer-antimicrobial peptide layer compound structure, the antimicrobial peptide formula has the advantages of long-lasting effect, efficient sterilization, anti-infection capability, anti-microbial and anti-apoptosis activity, capability of supporting conglutination, survival, growth and differentiation of various cells (such as osteoblast and chondrocyte) and wide application prospect.
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Description

technical field

[0001] The invention belongs to the technical field of dental implants, and in particular relates to a preparation method of an antibacterial peptide formula for dental implants. Background technique

[0002] With the continuous development of dental implant technology and wide recognition by patients, it is also the fastest-growing specialty in stomatology in recent years. It has continuously made breakthroughs and is providing professional help to more patients with dental diseases. However, another current situation that has to be admitted is that the existing interventional devices are prone to infection after being implanted in the body. The main infection mechanism is that the bacteria entering the body first adhere to the surface of the material, and due to the rich nutrient environment in the body, the bacteria reproduce and form a protective biofilm. The presence of biofilms makes infections from medical devices particularly difficult to treat. [...

Claims

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