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A honeysuckle flower stem and leaf feed additive capable of preventing and treating poultry bacterium and virus infectious diseases, a preparing method thereof and applications of the feed additive

A feed additive and infectious disease technology, applied in the field of poultry breeding, can solve problems such as affecting the efficiency of livestock and poultry breeding, bacterial resistance to antibiotics, easily induced allergic reactions, etc. effect of drug resistance

Inactive Publication Date: 2017-04-19
河北京阳生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the long-term use or abuse of antibiotics, its negative effects are becoming increasingly apparent, which not only affects the efficiency of livestock and poultry breeding, but also can cause problems such as bacterial resistance and antibiotic residues. When people eat poultry containing antibiotic residues for a long time, it is not only easy to induce Anaphylaxis and other clinical symptoms, endangering health, but also causing social problems such as environmental pollution

Method used

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  • A honeysuckle flower stem and leaf feed additive capable of preventing and treating poultry bacterium and virus infectious diseases, a preparing method thereof and applications of the feed additive
  • A honeysuckle flower stem and leaf feed additive capable of preventing and treating poultry bacterium and virus infectious diseases, a preparing method thereof and applications of the feed additive
  • A honeysuckle flower stem and leaf feed additive capable of preventing and treating poultry bacterium and virus infectious diseases, a preparing method thereof and applications of the feed additive

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0022] As an embodiment of the present invention, the feed additive contains 50-100% by weight of the honeysuckle stem and leaf water extract, and each gram of the honeysuckle stem and leaf water extract contains >3g of crude drug.

[0023] The present invention relates to a method for preparing the feed additive for preventing and treating bacterial and viral infectious diseases of poultry, wherein the method comprises: mechanically pulverizing the raw material into a powder with a particle size of less than 0.85 mm to obtain the Feed additives.

[0024] The present invention relates to a method for preparing the feed additive for preventing and treating bacterial and viral infectious diseases of poultry, wherein, the method comprises: step (1), pulverizing the raw material into powder; step (2), crushing The raw material powder obtained in the step (1) is added with a solvent, the solvent is water, ethanol or hydrous ethanol, the weight ratio of the raw material powder to th...

example 1

[0035] The active component analysis of example 1 honeysuckle stem, leaf and flower

[0036] Analytical instruments and raw materials:

[0037] Constant temperature drying oven is German Memmert type

[0038] Electronic balance Sartorius BP211D, precision one hundred thousandth

[0039] Grinder Hangzhou Xionghuo Technology Co., Ltd.

[0040] Ultrapure water meter Merck millipore company

[0041] Analytical HPLC Dionex Ultimate 3000 Series

[0042] Low resolution mass spectrometer Bruker amazon SL ion trap mass spectrometer

[0043] The analytical chromatographic column is Phenomenex Gemini 5μC18 110A (5μm, 250×4.6mm). The experimental samples are provided by Julu Jingding Murad Honeysuckle Industrial Park.

[0044] The active components of honeysuckle stems and leaves were analyzed by HPLC-MS method. The preparation of the test solution is to take 0.5g of honeysuckle powder, honeysuckle leaf powder, and honeysuckle stem powder respectively, accurately weigh them, place the...

example 2

[0050] The preparation of example 2 feed additives of the present invention

[0051] The feed additive of the present invention can be in two forms of mechanical micropowder and extract.

[0052] 2.1 Preparation of honeysuckle stem and leaf powder

[0053] The stems and leaves obtained when pruning honeysuckle plants in season are used as raw materials, washed, dried, and mechanically crushed into powder, the particle diameter of which is less than 0.85 mm (20 mesh), to obtain the fine powder of honeysuckle stems and leaves of the present invention.

[0054] 2.2 Preparation of honeysuckle stem and leaf water extract

[0055] Stems and leaves obtained when pruning honeysuckle plants in season are used as raw materials and prepared according to the following steps:

[0056] Step (1), crushing the raw material into powder; step (2), adding 10 times the amount of water to the raw material powder obtained in step (1), heating to boiling, extracting for 30 minutes, and filtering t...

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Abstract

A feed additive capable of preventing and treating poultry bacterium and virus infectious diseases is provided. Raw materials of the feed additive comprise honeysuckle flower stems and leaves. The feed additive has advantages of capability of preventing and treating bacterium and virus infectious diseases, capability of avoiding use of antibiotic medicines, no medicine residue, no drug resistance and no side or toxic effects. A preparing process of the feed additive is simple, low in energy consumption, pollution-free, safe and convenient. The feed additive is easy to store and has definite medicine effects. Industrialization can be achieved easily. The feed additive has good economic benefit and social benefit.

Description

technical field [0001] The invention belongs to the technical field of poultry breeding, and specifically relates to feed additives, feeds, preparation methods and applications thereof for preventing and treating bacterial and viral infectious diseases of poultry. Background technique [0002] In recent years, with the improvement of people's living standards, the consumption of poultry has also increased year by year, which has effectively driven the continuous development of domestic poultry intensive farming. However, in the poultry breeding industry, poultry diseases caused by high-density feeding and various pathogenic bacteria are becoming more and more serious, especially poultry diseases induced by pathogenic bacteria such as Escherichia coli and Salmonella, which seriously endanger the development of the aquaculture industry. Among them, Salmonella gallinarum is the pathogen of various diseases such as chicken typhoid, pullorum, and chicken paratyphoid. Studies so ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K50/75A23K10/30A61K36/355A61P31/04A61P31/12
CPCA61K36/355A61K2236/331A61K2236/39
Inventor 陈振兴栗原博
Owner 河北京阳生物医药科技有限公司
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