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Periplaneta americana anticancer active peptide and preparation method thereof

A technology of Periplaneta americana and anti-cancer activity, applied in the direction of organic active ingredients, pharmaceutical formulas, anti-tumor drugs, etc., can solve problems such as disharmony, and achieve the effect of enhancing curative effect, enhancing efficacy, and easy absorption and utilization

Pending Publication Date: 2017-04-26
赵德润
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The high cost of cancer treatment has caused a heavy burden on families and society. Many families have become impoverished due to cancer, which has brought many disharmonious and unstable factors to the society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] The present invention will be further described below in conjunction with embodiment

[0023] Embodiment 1. 1. Preparation of active peptide liquid of Periplaneta americana: select 30 kg of fresh and clean Periplaneta americana in that year for crushing; add purified water 15 times the weight of Periplaneta americana to homogenate with a tissue crusher, and Periplaneta homogenate was boiled in a cooking pot for 50 minutes, then allowed to cool, and the upper layer of oil was collected and discarded. Adjust the PH value of the defatted Periplaneta americana homogenate to 7, add keratinase, flavor protease, papain (1:1:1) multi-enzyme for enzymolysis, and the enzyme dosage is 10000 enzyme activity units per gram of Periplaneta americana ( u), the temperature is controlled at 55 degrees Celsius, after 8 hours of enzymatic hydrolysis; add 1% of the weight of Periplaneta americana yeast powder for deodorization, the temperature is controlled at 40 degrees Celsius and stirred...

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PUM

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Abstract

The invention relates to the field of traditional Chinese medicine and biotechnology, particularly to a periplaneta americana anticancer active peptide with functions of body resistance strengthening, constitution cultivating, blood circulation activation, blood stasis dissipating, cancer resistance and detoxification, and a preparation method thereof. The preparation method comprises: crushing periplaneta americana, homogenizing, cooking, carrying out enzymolysis, deodorizing, and centrifugating to obtain a periplaneta americana active peptide liquid; crushing Chinese herbs, cooking, carrying out enzymolysis, deodorizing, and centrifugating to obtain a Chinese herb active peptide liquid; adding oligoisomaltose and a grape seed extract, carrying out compounding sterilization, and filling according to oral liquid production process specifications to form an oral liquid product; carrying out filling and freeze drying according to freeze drying process specifications to form a bottled freeze drying powder product; and carrying out spray drying or freeze drying on the mixed peptide liquid to prepare powder-like particles, and filling according to capsule production process specifications to form the capsule product, wherein the raw materials comprise, by weight, 10-40% of the periplaneta americana active peptide, 5-40% of the traditional Chinese medicine active peptide, 5-15% of the oligoisomaltose, and 1-5% of the grape seed extract. According to the present invention, the preparation process is reasonable, and the method is suitable for large scale production.

Description

technical field [0001] The invention relates to the fields of traditional Chinese medicine and biotechnology, in particular to a cockroach active peptide with the functions of strengthening the body, promoting blood circulation and removing stasis, and anticancer and detoxifying functions, and a preparation method thereof. Background technique [0002] Now, cancer has become one of the factors that seriously endanger human health and destroy family and social harmony. Cancer experts believe that it is mainly caused by three types of carcinogens: physical carcinogens, such as ionizing radiation, X-rays, ultraviolet rays, etc. ; chemical carcinogens, such as arsenic, benzene, coal tar, methanol, etc.; viral carcinogens, such as hepatitis B virus, hepatitis C virus, etc. Carcinogens often harm humans in various ways through various media. Food and air pollution are the main causes of cancer. Common carcinogenic foods mainly include moldy foods, smoked foods, and submerged foo...

Claims

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Application Information

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IPC IPC(8): A61K38/01A61K9/08A61K9/19A61K9/16A61K9/48A61P35/00A61K35/64A61K35/36A61K35/57A61K36/258A61K36/488A61K36/41A61K36/84A61K31/702A61K31/352
CPCA61K38/011A61K38/012A61K9/0095A61K9/1605A61K9/19A61K9/4841A61K31/352A61K31/702A61K35/36A61K35/57A61K35/63A61K36/258A61K36/41A61K36/488A61K36/84A61K2236/51A61K2236/53A61K2236/19A61K2300/00
Inventor 赵德润
Owner 赵德润
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