Preparation method of a graphene-type nanocomposite hydrogel with anti-notch sensitivity

Abstract

The invention discloses a preparation method of an anti-notch-sensitivity graphene-type nano composite aquagel. By using the graphene-oxide-carried supported microgel as a crosslinking agent, the nano composite aquagel has the two crosslinking modes (physical crosslinking and chemical crosslinking), and thus, has favorable ductility and mechanical strength. The inside of the nano composite aquagel has high crosslinking density and complex crosslinking mode, and thus, the material can have favorable energy dissipation mechanism in case of cracking, and can still keep favorable ductility and mechanical strength when a notch appears in the aquagel.

Description

technical field

[0001] The invention relates to a method for preparing a hydrogel, in particular to a method for preparing a notch-resistant graphene-type nanocomposite hydrogel, and belongs to the technical field of nanomaterials. Background technique

[0002] Polymer hydrogel is a three-dimensional polymer network that can absorb and retain a large amount of water. Cross-linking by certain chemical or physical means prevents polymer chains with hydrophilic functional groups from being dispersed in the aqueous phase. Due to its high water content and other characteristics, hydrogels have been widely used in biological tissue engineering, drug release carriers, and high-sensitivity sensors in recent years. Due to the poor mechanical properties of traditional hydrogels, the application fields of hydrogels are greatly limited.

[0003] In recent years, although great progress has been made in improving the mechanical properties of hydrogels, such as the design and preparation...

Examples

Embodiment 1

[0025] 1. Prepare 25mL of graphene oxide dispersion with a mass fraction of 0.6%, and pass nitrogen gas for 15min, heat to 70°C; weigh 0.565g N-isopropylacrylamide, 0.03g N,N-dimethylbis Add acrylamide and 0.03 g of potassium persulfate to the graphene oxide dispersion, and react for 15 minutes under a nitrogen atmosphere to obtain a graphene oxide-loaded microgel composite nanomaterial dispersion.

[0026] 2. Place the dispersion liquid obtained in step 1 in an ice-water bath, and pass nitrogen gas for 5 minutes, weigh 15% of the mass of the dispersion liquid, and add acrylamide, a hydrophilic monomer, into the dispersion liquid, stir and dissolve, and then add 0.4% of the mass of the dispersion liquid % accelerator tetramethylethylenediamine, stir and disperse evenly, and place in a vacuum drying oven to remove the air bubbles in the dispersion, and the whole process is completed under an ice-water bath;

[0027] 3. The mixed solution obtained in step 2 was pre-polymerized f...

Embodiment 2

[0029] 1. Prepare 25mL of graphene oxide dispersion liquid with a mass fraction of 0.6%, and inject nitrogen gas for 15min, and heat to 70°C;

[0030] 2. Place the dispersion liquid obtained in step 1 in an ice-water bath, and pass nitrogen gas for 5 minutes, weigh 15% of the mass of the dispersion liquid, and add acrylamide, a hydrophilic monomer, into the dispersion liquid, stir and dissolve, and then add 0.4% of the mass of the dispersion liquid % accelerator tetramethylethylenediamine, stir and disperse evenly, and place in a vacuum drying oven to remove the air bubbles in the dispersion, and the whole process is completed under an ice-water bath;

[0031] 3. Pre-polymerize the mixed solution obtained in step 2 for 2 hours in an ice bath, and then transfer it to a 60° C. oven for polymerization for 12 hours to obtain a graphene nanocomposite hydrogel.

Embodiment 3

[0033] 1. Inject nitrogen gas into 25mL deionized water for 15min, and heat to 70°C; weigh 0.565g N-isopropylacrylamide, 0.03g N,N-dimethylbisacrylamide and 0.03g potassium persulfate in sequence Adding it into the graphene oxide dispersion, and reacting for 15 minutes under a nitrogen atmosphere, to obtain a graphene oxide-loaded microgel composite nanomaterial dispersion.

[0034] 2. Place the dispersion liquid obtained in step 1 in an ice-water bath, and pass nitrogen gas for 5 minutes, weigh 15% of the mass of the dispersion liquid, and add acrylamide, a hydrophilic monomer, into the dispersion liquid, stir and dissolve, and then add 0.4% of the mass of the dispersion liquid % accelerator tetramethylethylenediamine, stir and disperse evenly, and place in a vacuum drying oven to remove the air bubbles in the dispersion, and the whole process is completed under an ice-water bath;

[0035] 3. The mixed solution obtained in step 2 was pre-polymerized for 2 hours in an ice bath...

technical field

[0001] The invention relates to a method for preparing a hydrogel, in particular to a method for preparing a notch-resistant graphene-type nanocomposite hydrogel, and belongs to the technical field of nanomaterials. Background technique

[0002] Polymer hydrogel is a three-dimensional polymer network that can absorb and retain a large amount of water. Cross-linking by certain chemical or physical means prevents polymer chains with hydrophilic functional groups from being dispersed in the aqueous phase. Due to its high water content and other characteristics, hydrogels have been widely used in biological tissue engineering, drug release carriers, and high-sensitivity sensors in recent years. Due to the poor mechanical properties of traditional hydrogels, the application fields of hydrogels are greatly limited.

[0003] In recent years, although great progress has been made in improving the mechanical properties of hydrogels, such as the design and preparation...

Examples

Embodiment 1

[0025] 1. Prepare 25mL of graphene oxide dispersion with a mass fraction of 0.6%, and pass nitrogen gas for 15min, heat to 70°C; weigh 0.565g N-isopropylacrylamide, 0.03g N,N-dimethylbis Add acrylamide and 0.03 g of potassium persulfate to the graphene oxide dispersion, and react for 15 minutes under a nitrogen atmosphere to obtain a graphene oxide-loaded microgel composite nanomaterial dispersion.

[0026] 2. Place the dispersion liquid obtained in step 1 in an ice-water bath, and pass nitrogen gas for 5 minutes, weigh 15% of the mass of the dispersion liquid, and add acrylamide, a hydrophilic monomer, into the dispersion liquid, stir and dissolve, and then add 0.4% of the mass of the dispersion liquid % accelerator tetramethylethylenediamine, stir and disperse evenly, and place in a vacuum drying oven to remove the air bubbles in the dispersion, and the whole process is completed under an ice-water bath;

[0027] 3. The mixed solution obtained in step 2 was pre-polymerized f...

Embodiment 2

[0029] 1. Prepare 25mL of graphene oxide dispersion liquid with a mass fraction of 0.6%, and inject nitrogen gas for 15min, and heat to 70°C;

[0030] 2. Place the dispersion liquid obtained in step 1 in an ice-water bath, and pass nitrogen gas for 5 minutes, weigh 15% of the mass of the dispersion liquid, and add acrylamide, a hydrophilic monomer, into the dispersion liquid, stir and dissolve, and then add 0.4% of the mass of the dispersion liquid % accelerator tetramethylethylenediamine, stir and disperse evenly, and place in a vacuum drying oven to remove the air bubbles in the dispersion, and the whole process is completed under an ice-water bath;

[0031] 3. Pre-polymerize the mixed solution obtained in step 2 for 2 hours in an ice bath, and then transfer it to a 60° C. oven for polymerization for 12 hours to obtain a graphene nanocomposite hydrogel.

Embodiment 3

[0033] 1. Inject nitrogen gas into 25mL deionized water for 15min, and heat to 70°C; weigh 0.565g N-isopropylacrylamide, 0.03g N,N-dimethylbisacrylamide and 0.03g potassium persulfate in sequence Adding it into the graphene oxide dispersion, and reacting for 15 minutes under a nitrogen atmosphere, to obtain a graphene oxide-loaded microgel composite nanomaterial dispersion.

[0034] 2. Place the dispersion liquid obtained in step 1 in an ice-water bath, and pass nitrogen gas for 5 minutes, weigh 15% of the mass of the dispersion liquid, and add acrylamide, a hydrophilic monomer, into the dispersion liquid, stir and dissolve, and then add 0.4% of the mass of the dispersion liquid % accelerator tetramethylethylenediamine, stir and disperse evenly, and place in a vacuum drying oven to remove the air bubbles in the dispersion, and the whole process is completed under an ice-water bath;

[0035] 3. The mixed solution obtained in step 2 was pre-polymerized for 2 hours in an ice bath...

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