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Florfenicol dry suspension agent and preparation method thereof

A technology of florfenicol and suspension, which is applied in the field of animal medicine and its manufacturing, can solve the problems of young piglets eating less food and inconvenient use, and achieve various and convenient clinical administration methods, fine particles, and reduced irritation Effect

Inactive Publication Date: 2017-05-24
金河牧星(重庆)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, Florfenicol itself is insoluble in water, and it is generally used for oral administration in mixed feeding in clinical practice. It is inconvenient for young piglets to eat less food.

Method used

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  • Florfenicol dry suspension agent and preparation method thereof
  • Florfenicol dry suspension agent and preparation method thereof

Examples

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preparation example Construction

[0074] The present invention also provides a preparation method of florfenicol powder dry suspension, comprising the following steps:

[0075] Step 1: Take the prescribed amount of suspending agent and grind it, grind it and sieve it, then stir and mix until the powder has uniformity, no patterns and no color spots, and prepare it into A powder for later use;

[0076] Step 2: take the prescribed amount of florfenicol, montmorillonite, and buffalo horn extracts, grind them, sieve them after grinding, and then stir and mix until the powder has no patterns and no color spots in uniformity, and prepares B powder;

[0077] Step 3: Add the above A powder to B powder according to the same amount of addition and stir evenly, then add an appropriate amount of carrier and continue to stir and mix until the uniformity of the powder is checked, there are no patterns and color spots, and then sieve to obtain Florfenicol powder dry blend Suspension.

[0078] In some embodiments of the pres...

Embodiment 1

[0093] Example 1: Florfenicol powder: 10 parts, montmorillonite: 20 parts, buffalo horn extract: 5 parts, bentonite: 5 parts, sodium citrate: 5 parts, sodium carboxymethylcellulose: 3 parts 2 parts, 2 parts of sodium saccharin, 50 parts of soluble starch.

Embodiment 2

[0094] Example 2: 15 parts of florfenicol powder, 25 parts of montmorillonite, 8 parts of buffalo horn extract, 8 parts of bentonite, 8 parts of sodium citrate, 4 parts of sodium carboxymethylcellulose, anhydrous glucose 32 servings.

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Abstract

The invention provides a florfenicol dry suspension agent. The florfenicol dry suspension agent is prepared from the following raw materials in parts by weight: 10-20 parts of florfenicol, 20-30 parts of montmorillonite, 5-10 parts of cornu bubali extract, 27-40 parts of a carrier and 13-25 parts of an auxiliary suspending agent. Compared with the prior art, the florfenicol dry suspension agent provided by the invention has the beneficial effects that the montmorillonite has a carrier function of the florfenicol dry suspension agent and a chemical function improving function; the chemical irritation of the florfenicol can be controlled very well and the florfenicol can be orally taken through drinking water; and the florfenicol can be used for cooperatively controlling piglet diarrhea symptoms.

Description

technical field [0001] The invention relates to the related technical field of animal medicine and its manufacture, more specifically, relates to a dry suspension of florfenicol powder and a preparation method thereof. Background technique [0002] The antibacterial spectrum and antibacterial activity of florfenicol powder are slightly better than thiamphenicol, and it has strong antibacterial activity against a variety of gram-positive bacteria, gram-negative bacteria and mycoplasma. Pasteurella hemolyticus, Pasteurella multocida, and Actinobacillus pleurisy are highly sensitive to this product, and to streptococcus, thiamphenicol-resistant Shigella dysenteriae, Salmonella typhi, Klebsiella, Escherichia coli bacilli and ampicillin-resistant Haemophilus influenzae were susceptible. [0003] It is mainly used for bacterial diseases of cattle, pigs, chickens and fish, such as cattle respiratory diseases caused by Pasteurella and Haemophilus bacillus, bovine infectious keratoc...

Claims

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Application Information

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IPC IPC(8): A61K35/32A61K31/165A61K9/14A61K47/38A61P31/04A61P1/12A61K33/06
CPCA61K35/32A61K9/146A61K31/165A61K33/06A61K2300/00
Inventor 秦斌周建唐文龙何丽花
Owner 金河牧星(重庆)生物科技有限公司
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