Preparation method of arabic gum hollow nanospheres

A kind of gum arabic and hollow nanotechnology, applied in nanotechnology, nanotechnology, nanotechnology for materials and surface science, etc., can solve the problems of poor compatibility between metal nanoparticles and shell materials, unfavorable compounds, environmental pollution, etc. , to achieve the effect of low cost, high repeatability and uniform particle size distribution

Active Publication Date: 2017-05-31
QINGDAO AGRI UNIV
View PDF3 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, the metal nanoparticle hard template method to prepare hollow nanoparticles is currently the most widely used method for preparing hollow nanoparticles. However, the compatibility between metal nanoparticles and shell materials (organic nanoparticles, biomacromolecules) is poor, which is not conducive to the formation of stable Composite, when removing the hard template of metal nanoparticles, it usually needs to use acid, alkali, etc. to carry out intense chemical reactions, which is easy to cause environmental pollution and high energy consumption
Moreover, the application of metal nanoparticles in the fields of medicine and food also has certain safety hazards.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of arabic gum hollow nanospheres
  • Preparation method of arabic gum hollow nanospheres
  • Preparation method of arabic gum hollow nanospheres

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Prepare gum arabic hollow nanospheres with different shell-core ratios according to the following steps:

[0030] (1) Preparation of buffer solution: Accurately weigh 3.27g of disodium hydrogen phosphate and 2.24g of citric acid and dissolve them in 200mL of distilled water, stir to fully dissolve, and set aside;

[0031] (2) Pullulanase pretreatment: Accurately measure 1 mL of pullulanase with a concentration of 1350 NPUN / mL and drop it into 10 mL of distilled water, stir to make it fully mixed, and set aside;

[0032] (3) Preparation of starch milk: Weigh 15 g of waxy cornstarch and add it to 100 mL of buffer solution to obtain a starch emulsion with a mass volume ratio of 15%;

[0033] (4) Gelatinization: put the prepared starch milk in a water bath at 100°C for 20 minutes to completely gelatinize the starch, and then cool down to 58°C;

[0034] (5) Enzymolysis: add 1.5 mL of treated pullulanase to the gelatinized colloidal starch solution, and enzymatically hydroly...

Embodiment 2

[0066] (1) Preparation of buffer solution: Accurately weigh 1.635g of disodium hydrogen phosphate and 1.12g of citric acid and dissolve in 100mL of distilled water, stir to fully dissolve, and set aside;

[0067] (2) Pullulanase pretreatment: Accurately measure 1 mL of pullulanase with a concentration of 1350 NPUN / mL and drop it into 9 mL of distilled water, stir to make it fully mixed, and set aside;

[0068] (3) Preparation of starch milk: Weigh 10 g of waxy cornstarch and add it to 100 mL of buffer solution to prepare a starch emulsion with a mass volume ratio of 10%;

[0069] (4) Gelatinization: Put the prepared starch milk in a water bath at 100°C for 40 minutes to completely gelatinize the starch, then cool down to 55°C;

[0070] (5) Enzymolysis: add 1 mL of the treated pullulanase to the gelatinized colloidal starch solution, and enzymatically hydrolyze at 55°C for 6 hours;

[0071] (6) Low-speed centrifugation: centrifuge the solution obtained while hot at a speed of ...

Embodiment 3

[0079] (1) Preparation of buffer solution: Accurately weigh 6.54g of disodium hydrogen phosphate and 4.48g of citric acid and dissolve in 400mL of distilled water, stir to fully dissolve, and set aside;

[0080] (2) Pullulanase pretreatment: Accurately measure 1 mL of pullulanase with a concentration of 1350 NPUN / mL and drop it into 8 mL of distilled water, stir to make it fully mixed, and set aside;

[0081] (3) Preparation of starch milk: Weigh 20 g of waxy cornstarch and add it to 100 mL of buffer solution to obtain a starch emulsion with a mass volume ratio of 20%;

[0082] (4) Gelatinization: put the prepared starch milk in a water bath at 100°C for 50 minutes to completely gelatinize the starch, and then cool down to 60°C;

[0083] (5) Enzymolysis: add 2 mL of the treated pullulanase to the gelatinized colloidal starch solution, and enzymatically hydrolyze at 60°C for 6 hours;

[0084] (6) Low-speed centrifugation: centrifuge the solution obtained while hot at a speed o...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a preparation method of arabic gum hollow nanospheres. The method comprises the following steps: firstly preparing starch with short amylose by using a biological enzyme method, adding arabic gum into the short amylose to coat and form starch nanoparticles, then carrying out enzymolysis of the starch by using alpha-amylase to obtain the arabic gum hollow nanospheres. The preparation method of arabic gum hollow nanospheres is low in equipment requirement, simple in process, simple and convenient to operate, mild in reaction, short in reaction time and high in efficiency, and is suitable for large-scale production; the product performance is high; the particle size of the prepared arabic gum hollow nanospheres is 60-85nm; the ratio of diameter of core to diameter of shell can be controlled by adjusting the ratio of arabic gum to the short amylase, and the shell thickness controlling effect can be achieved; the preparation cost is low; the energy consumption is low; no hazardous waste is generated; the modern production requirements of green production, environment friendliness and energy economization can be met.

Description

technical field [0001] The invention belongs to the technical field of nanomaterials, in particular to a method for preparing gum arabic hollow nanospheres by hydrolyzing starch nanoparticle templates with α-amylase. Background technique [0002] In recent years, hollow nanoparticles have become a research hotspot in the fields of medicine and food, and are often used for the embedding and delivery of active substances and drugs. Among them, the metal nanoparticle hard template method to prepare hollow nanoparticles is currently the most widely used method for preparing hollow nanoparticles. However, the compatibility between metal nanoparticles and shell materials (organic nanoparticles, biomacromolecules) is poor, which is not conducive to the formation of stable When removing the metal nanoparticle hard template, it usually needs to use acid, alkali, etc. to carry out intense chemical reactions, which is easy to cause environmental pollution and high energy consumption. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C08J3/12C08L5/00C08L3/02C12P19/16C12P19/14C12P19/02B82Y30/00B82Y40/00
CPCB82Y30/00B82Y40/00C08J3/12C08J3/126C08J2305/00C08J2403/02C12P19/02C12P19/14C12P19/16
Inventor 孙庆杰熊柳李晓静姬娜卢浩
Owner QINGDAO AGRI UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap