Rivaroxaban tablet
A technology of rivaroxaban and beta-cyclodextrin, which is applied in the direction of non-active ingredient medical preparations, pill delivery, blood diseases, etc., can solve the problem of failure to provide rivaroxaban tablets, etc., and achieve drug dissolution Rapid, uniform drug dispersion and smooth production process
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Embodiment 1
[0032]
[0033]
[0034] Preparation Process:
[0035] Dissolve rivaroxaban, hydroxypropyl beta-cyclodextrin, and deoxycholic acid in ethyl acetate, then granulate the solution on lactose and crospovidone, dry at 40°C, and sizing on a 20-mesh sieve , Magnesium stearate is added to dry granules, mixed evenly, and compressed into tablets.
Embodiment 2
[0037]
[0038] Preparation workers:
[0039] Dissolve rivaroxaban, hydroxypropyl betacyclodextrin, and deoxycholic acid in ethyl acetate, then granulate the solution on lactose and croscarmellose sodium, dry at 40°C, 20 mesh Sieve the granules, add magnesium stearate to the dry granules, mix them evenly, and compress them.
Embodiment 3
[0041]
[0042] Preparation Process:
[0043] Dissolve rivaroxaban, hydroxypropyl beta-cyclodextrin, and deoxycholic acid in ethyl acetate, then granulate the solution on mannitol and sodium carboxymethyl starch, dry at 40°C, and sieving with 20 mesh , Magnesium stearate is added to dry granules, mixed evenly, and compressed into tablets.
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