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An ulcer-healing bowel-relaxing enema biofluid film and a preparing method thereof

A biological fluid and enema technology, applied in the directions of liquid delivery, drug combination, drug delivery, etc., can solve problems such as toxic and side effects of radiotherapy and chemotherapy, and achieve the effect of inhibiting bacterial growth, good antibacterial effect, and preventing the growth of pathogenic bacteria.

Inactive Publication Date: 2017-07-04
JIANGSU HAIERZI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, in tumor treatment, it is often difficult to meet the ideal requirements: the toxic and side effects of radiotherapy and chemotherapy are obvious to all
Although in recent years, in the development of new drugs and new methods, the reduction of toxicity has been regarded as one of the goals of research, but the toxicity of radiotherapy and chemotherapy has become a major difficulty in clinical treatment.

Method used

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  • An ulcer-healing bowel-relaxing enema biofluid film and a preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Raw material ratio:

[0052] Water-soluble hydroxypropyl chitosan 0.5%

[0053] Water-soluble sodium alginate (C6H7O6Na)n 0.2%

[0054] Grapefruit Seed Extract (GSE): 1.0%

[0055] Electrolyte: Sodium Chloride 0.5%

[0056] Potassium chloride 0.02%

[0057] Calcium chloride 0.03%

[0058] Regulating osmotic pressure substances:

[0059] Glycerin 4.0%

[0060] Water for injection: 93.75%.

[0061] The preparation method of enema biological fluid film is prepared according to the following steps:

[0062] Step 1) Put the water-soluble hydroxypropyl chitosan in 200ml of water for injection to fully soak and swell until it is completely dissolved to obtain a liquid , which is ready for use;

[0063] Step 2) Put the water-soluble sodium alginate in 200ml of water for injection to fully soak and swell until it is completely dissolved to obtain a liquid for later use;

[0064] Step 3) Dissolve sodium chloride, potassium chloride and calcium chloride directly in 100ml ...

Embodiment 2

[0070] Raw material ratio:

[0071] Water-soluble hydroxypropyl chitosan 0.4%

[0072] Water-soluble sodium alginate (C6H7O6Na)n 0.1%

[0073] Grapefruit Seed Extract (GSE): 0.5%

[0074] Electrolyte: Sodium Chloride 0.5%

[0075] Potassium chloride 0.02%

[0076] Calcium chloride 0.03%

[0077] Regulating osmotic pressure substances:

[0078] Glycerin 3.0%

[0079] Water for injection: 95.85%.

[0080] The preparation method of enema biological fluid film is prepared according to the following steps:

[0081] Step 1) Put the water-soluble hydroxypropyl chitosan in 200ml of water for injection to fully soak and swell until it is completely dissolved to obtain a liquid , which is ready for use;

[0082] Step 2) Put the water-soluble sodium alginate in 200ml of water for injection to fully soak and swell until it is completely dissolved to obtain a liquid for later use;

[0083] Step 3) Dissolve sodium chloride, potassium chloride and calcium chloride directly in 100ml ...

Embodiment 3

[0089] Raw material ratio:

[0090] Water-soluble hydroxypropyl chitosan 0.6%

[0091] Water-soluble sodium alginate (C6H7O6Na)n 0.3%

[0092] Grapefruit Seed Extract (GSE) 0.5%

[0093] Electrolyte: Sodium Chloride 0.4%

[0094] Potassium chloride 0.015%

[0095] Calcium chloride 0.03%

[0096] Regulating osmotic pressure substances:

[0097] Glycerin 4.0%

[0098] Water for injection: 94.155%.

[0099] The preparation method of enema biological fluid film is prepared according to the following steps:

[0100] Step 1) Put the water-soluble hydroxypropyl chitosan in 200ml of water for injection to fully soak and swell until it is completely dissolved to obtain a liquid , which is ready for use;

[0101] Step 2) Put the water-soluble sodium alginate in 200ml of water for injection to fully soak and swell until it is completely dissolved to obtain a liquid for later use;

[0102] Step 3) Dissolve sodium chloride, potassium chloride and calcium chloride directly in 100ml...

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Abstract

An ulcer-healing bowel-relaxing enema biofluid film and a preparing method thereof are disclosed. The enema biofluid film is suitable for treatment on radiation enteritis, chronic ulcerative colitis, enteritis and habitual constipation and preparatory treatment before digestive tract and intestinal tract operations and enteroscopy, and is applied for performing enema therapy on patients with diabetic nephropathy, chronic nephropathy, renal failure and uremia to expel toxins through intestinal tracts so as to assist dialysis. The biofluid film is prepared into a hypertonic or isotonic, sterile, colorless or light yellow, transparent and thick biofluid film. The biofluid film can stimulate intestinal tract shrinkage to achieve constipation-relieving and bowel-relaxing functions; the biofluid film can supplement nutrition, deeply expel toxins and has a high adsorption function, thus achieving a function of deeply expelling toxins in intestinal tracts and the blood biofluid film; the biofluid film can form a protective film on the inner wall of the intestinal tract so as to promote ulcer surface healing; and the biofluid film has a function of adjusting flora balance in the intestinal tract.

Description

technical field [0001] The present invention relates to an enema biofluid membrane for curing ulcers and laxatives and a preparation method thereof. The enema biofluid membrane is applied to the treatment of radiation enteritis, chronic ulcerative colitis, enteritis and habitual constipation, as well as digestive tract and intestinal surgery, intestinal It can also be used as a preparatory treatment before endoscopy, and can also be used in patients with diabetic nephropathy, chronic kidney disease, renal failure and uremia to assist dialysis through intestinal detoxification. Background technique [0002] Constipation is currently a common anorectal disease, which refers to induration of stool, difficulty or incomplete defecation, and decreased frequency of defecation. If the patient delays defecation arbitrarily for a long time, the rectum will lose its normal sensitivity to the stimulation of feces pressure, and the feces will accumulate in the rectum for a long time with...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/06A61P1/04A61P1/10A61P1/00A61P7/08A61K31/722A61K31/734
CPCA61K9/0031A61K9/06A61K31/722A61K31/734A61K36/752A61K47/10A61K2300/00
Inventor 胡军胡梦
Owner JIANGSU HAIERZI BIOTECH CO LTD
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