An individualized and customized zirconia porous biological bone repair scaffold based on light-curing 3D printing technology and its preparation method

Abstract

The invention relates to a preparation method of a biological ceramic scaffold material, in particular to a preparation method of a zirconium dioxide porous biologic bone repair scaffold customized in an individualized way based on a light curing three-dimensional (3D) printing technology. The method comprises the following steps: (1) establishing a health status chart of a bone, which is not damaged, by using a two-dimensional or three-dimensional imaging technology of computed tomography (CT), and separating out a form figure of a bone needing to be implanted in combination of a status chart of the damaged bone waiting for implanting; (2) using special data software to convert CT data into 3D print data; (3) preparing the zirconium dioxide porous biologic bone repair scaffold in the individualized way by using the light curing 3D printing technology. The bone repair biological ceramic material prepared by the method is in accordance with the individualized treatment principle; the method is short in manufacturing process time and high in efficiency; the prepared material is more accurate in porosity, small in error, high in compressive strength and bending strength and good in biocompatibility.

Description

technical field [0001] The invention relates to a preparation method of a bioceramic support material. Background technique [0002] With the incidence of traumatic fractures and bone tumors increasing year by year, more and more patients have bone defects caused by trauma and tumors. However, treatment, especially the treatment of large bone defects, has always been one of the difficult problems in the field of orthopedics. Large bone defects not only require a large amount of bone graft, but also have high requirements for postoperative mechanical properties. At present, the most widely used methods for clinical treatment of bone defects include bone grafting, artificial substitute replacement, and distraction osteogenesis, but each has its own limitations. For example, autologous bone extraction itself is a re-injury to the patient, which greatly increases the suffering of the patient, and the amount of donor bone is limited; the source of allogeneic bone and heterogeneo...

AI Technical Summary

Problems solved by technology

Therefore, an ideal stent is a complex three-dimensional structure composed of microstructures with an individualized shape and a certain regular distribution inside. Traditional manufacturing methods cannot solve the manufacturing problem of stents.

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