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Production process for probiotic periodontal care gel

A production process and probiotic technology, applied in oral care, dentistry, medical science and other directions, can solve the problems of reduced oral and dental protection, uncontrollable enzyme activity, single oral and dental care performance, etc., to prevent gingivitis and The occurrence of dental caries, the effect of improving the balance of oral flora and reducing the accumulation of plaque

Inactive Publication Date: 2017-08-22
江苏恩为众心生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] General functional full-effect toothpaste adds antibiotics to inhibit oral bacteria, and long-term use of antibiotics, bacteria are prone to drug resistance, and general functional toothpaste has single care performance for oral cavity and teeth, lacking comprehensive care functions
General enzyme preparation toothpaste cannot control the decay of enzyme activity, and cannot guarantee the activity of enzyme within the shelf life, so that the real use effect cannot be achieved, and the protection effect on the oral cavity and teeth is reduced.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] A kind of probiotic periodontal care gel production process of the present invention comprises the following steps:

[0014] (a) According to the formula ratio, heat purified water with a mass percentage of 74.625% to 35-40°C, add 0.52% by mass of sodium benzoate, 0.052% by mass of cetylpyridinium chloride, and Sodium fluoride with a content of 0.047% and sucralose with a mass percentage of 0.051%, amorphous sorbitol with a mass percentage of 17% (content is 70%), nisin with a mass percentage of 0.0045%, The mass percentage content is 0.00019% bright blue pigment, and stirred for 20-25 minutes to obtain solution I;

[0015] (b) Heat 0.9% by mass of RH40 hydrogenated castor oil and 1.1% by mass of propylene glycol until melted, add 0.1% by mass of peppermint essence, and stir evenly to obtain solution II;

[0016] (c) According to the formula ratio, PEG-400 with a mass percentage of 5%, xanthan gum with a mass percentage of 0.28% and sodium alginate with a mass percenta...

Embodiment 2

[0019] A kind of probiotic periodontal care gel production process of the present invention comprises the following steps:

[0020] (a) According to the formula ratio, heat 77.96% by mass of purified water to 35-40°C, add 0.55% by mass of sodium benzoate, 0.055% by mass of cetylpyridinium chloride, Sodium fluoride with a content of 0.06% and sucralose with a mass percentage of 0.055%, amorphous sorbitol with a mass percentage of 12% (content is 70%), nisin with a mass percentage of 0.0065%, The mass percentage content is 0.0002% bright blue pigment, and stirred for 20-25 minutes to obtain solution I;

[0021] (b) Heat 1.2% by mass of RH40 hydrogenated castor oil and 1.2% by mass of propylene glycol until melted, add 0.12% by mass of peppermint essence, and stir evenly to obtain solution II;

[0022] (c) According to the formula ratio, PEG-400 with a mass percentage of 6%, xanthan gum with a mass percentage of 0.4% and sodium alginate with a mass percentage of 0.4% were evenly...

Embodiment 3

[0025] A kind of probiotic periodontal care gel production process of the present invention comprises the following steps:

[0026] (a) According to the proportion of the formula, heat purified water with a mass percentage of 72.336% to 35-40°C, add 0.45% by mass of sodium benzoate, 0.045% by mass of cetylpyridinium chloride, and Sodium fluoride with a content of 0.04% and sucralose with a mass percentage of 0.045%, amorphous sorbitol with a mass percentage of 21% (content is 70%), nisin with a mass percentage of 0.0035%, The mass percentage content is 0.00016%% bright blue pigment, and stirred for 20-25 minutes to obtain solution I;

[0027] (b) Heat 0.8% by mass of RH40 hydrogenated castor oil and 0.8% by mass of propylene glycol to melt, add 0.08% by mass of peppermint essence, and stir evenly to obtain solution II;

[0028] (c) According to the formula ratio, PEG-400 with a mass percentage of 4%, xanthan gum with a mass percentage of 0.2% and sodium alginate with a mass p...

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Abstract

The invention discloses a production process for a probiotic periodontal care gel. The production process comprises the following steps: preparation of a solution I: heating purified water, then adding sodium benzoate, cetylpyridinium chloride, sodium fluoride, sucralose, noncrystalline sorbitol, nisin and brilliant blue and carrying out stirring for 20 to 25 min; preparation of a solution II: heating hydrogenated castor oil RH40 and propylene glycol to a fusion state, adding peppermint essence and carrying out uniform mixing under stirring so as to obtain the solution II; preparation of a solution III: uniformly mixing PEG-400, xanthan gum and sodium alginate in a ratio prescribed in a formula under stirring so as to obtain the solution III; and preparation of the probiotic periodontal care gel: adding the solution II into the solution I, carrying out uniform mixing under stirring, then adding the solution III, carrying out stirring for 25 to 30 min so as to form a semi-finished product, taking a sample for laboratory test so as to obtain a semi-finished cetylpyridinium chloride product, carrying out canning when the semi-finished cetylpyridinium chloride product is determined to be qualified and carrying out warehousing after a finished product is determined to be qualified, wherein if cetylpyridinium chloride is insufficient, cetylpyridinium chloride is added, a sample is taken for detection until the semi-finished product is qualified and then canning is carried out, and if the finished product is determined to be unqualified, the finished product is discarded. Lactobacillus can reinforce inhibitory effect of sodium fluoride on Streptococcus mutans, reduce accumulation of dental plaques, prevent gingivitis and carious teeth and improve the balance of microfloras in the oral cavity.

Description

technical field [0001] The invention relates to a production process of probiotic periodontal care jelly. Background technique [0002] General functional full-effect toothpaste is added with antibiotics to inhibit oral bacteria, and long-term use of antibiotics, bacteria are prone to drug resistance, and general functional toothpaste has a single care performance for the oral cavity and teeth, and lacks comprehensive care functions. General enzyme toothpaste cannot control the decay of enzyme activity, and cannot guarantee the activity of enzyme within the shelf life, so that the real use effect cannot be achieved, and the protective effect on oral cavity and teeth is reduced. [0003] Therefore, it is necessary to provide a new technical solution to solve the above problems. Contents of the invention [0004] The technical problem to be solved by the present invention is to provide a production process of probiotic periodontal care jelly with good nursing effect. [00...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/21A61K8/49A61Q11/00A61P1/02
CPCA61K8/99A61K8/21A61K8/4926A61Q11/00
Inventor 江晶晶张振平周建兵
Owner 江苏恩为众心生物医药有限公司
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