Method of rapidly degrading beta-lactam antibiotic in water

A lactam-based, rapid-degradation technology, applied in chemical instruments and methods, water pollutants, water/sewage treatment, etc., can solve problems such as high energy consumption, weak selectivity, and susceptibility to other pollutants in water bodies. Achieve the effect of low energy consumption, fast degradation rate and wide application range of pH

Active Publication Date: 2017-10-27
SUZHOU UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The problem to be solved by the present invention is to provide a low-efficiency solution for the current use of persulfate to degrade beta-lactam antibiotics requires external energy activation, high energy consumption, weak selectivity, and is easily affected by other pollutants in water bodies. A cost-effective, fast and efficient method for specifically degrading beta-lactam antibiotics in water

Method used

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  • Method of rapidly degrading beta-lactam antibiotic in water
  • Method of rapidly degrading beta-lactam antibiotic in water
  • Method of rapidly degrading beta-lactam antibiotic in water

Examples

Experimental program
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Effect test

Embodiment 1

[0027] Prepare concentration of 0.01mol / L potassium persulfate, potassium persulfate, silver sulfate, cobalt chloride solution and 1000 μmol / L cephalexin solution. The first step, to 6 containing 40 μ mol / L cephalexin (0.01mol / L phosphate buffer pH=7), numbering is successively 1,2,3,4,5,6 reaction vials (volume 100ml, placed in On the stirrer) add reagents according to the following conditions: No. 1 bottle is added with 4ml of cobalt chloride (final concentration is 400 μmol / L); No. 2 to No. / L, 200μmol / L, 400μmol / L); in the second step, add 4ml of potassium persulfate solution (final concentration is 400μmol / L) to No. 1 and No. Add 4ml of the potassium persulfate solution prepared above into the bottle respectively, and stir and react for a certain period of time at room temperature. The removal rate of cephalexin in this example is respectively: permonosulfate alone degrades 3min 100%, cobalt chloride activates permonosulfate 3min 76.4%; Potassium persulfate alone degrade...

Embodiment 2

[0029] Add different amounts of potassium persulfate solution into 100ml ultrapure water (0.01mol / L phosphate buffer pH=7) containing 40 μmol / L cephalexin, so that the final concentrations of potassium persulfate are 200 μmol / L and 400 μmol / L respectively. L, 600μmol / L, 800μmol / L, 1000μmol / L, 1200μmol / L, placed on a stirrer and stirred evenly, after a certain period of reaction, the removal of cephalexin by potassium persulfate of different concentrations was completed. The removal rates of cephalexin in this example were 94.5%, 94.9%, 95.1%, 95.5%, 94.7%, 95.8%.

Embodiment 3

[0031] Take 4ml of the prepared potassium persulfate solution and add 40 μmol / L of cephalexin (CFX), cefapirin (cefapirin), cefradine (cefradine), penicillin G (PG), ampicillin (AMP), amoxicillin 100ml of ultrapure water from cillin (AMX) was placed on a stirrer at room temperature and stirred evenly, and samples were taken at a specified time. That is, the degradation of different beta-lactam antibiotics by potassium persulfate is completed. In this example, the removal rates of CFX, cefapirin, cefradine, PG, AMP, and AMX were 94.9%, 97.1%, 93.1%, 93.9%, 97%, and 84.8%, respectively.

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Abstract

The invention relates to a method of rapidly degrading a beta-lactam antibiotic in water. The method concretely comprises the following steps: adding a certain quantity of peroxymonosulfate (PMS) as an oxidant in waste water which contains a beta-lactam antibiotic (such as cephalexin, i.e. CFX) at normal temperature and normal pressure, uniformly stirring, carrying out reaction for a period of time under a neutral condition while keeping a pH value of a system, and removing a pollutant with oxidative degradation. According to the method provided by the invention, the peroxymonosulfate as the oxidant has very high selectivity to the beta-lactam antibiotic, directly oxidizes and removes the pollutant without an additional persulfate activation step, is rapid in degradation with very little influence caused by other organic matters in a water body, and is more beneficial to removing the beta-lactam antibiotic in a polluted water body.

Description

technical field [0001] The invention relates to a method for removing antibiotics in water, in particular to a method for removing beta-lactam antibiotics by direct and rapid oxidation of persulfate in the field of water treatment of emerging pollutants. Background technique [0002] In recent years, with the development of social economy, the development of medical technology has been paid more and more attention, and the use of drugs has gradually increased. The ensuing problem is that more and more drugs enter the environment to have a certain impact on microorganisms, and then Potential threats to human health and the ecological environment. Among them, beta-lactam antibiotics are the most widely used family medical drugs. Traditional biological treatment methods cannot completely remove them from water bodies. Residual antibiotics that persist in water will increase bacterial resistance and generate drug resistance. Bacteria such as vancomycin-resistant enterococci, me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C02F1/72C02F101/38
CPCC02F1/722C02F2101/38
Inventor 陈家斌黄天寅房聪马晓琪
Owner SUZHOU UNIV OF SCI & TECH
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