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Three-layer water-containing capsules and preparation method thereof

A technology of water-containing capsules and water cores, which can be used in capsule delivery, pharmaceutical formulations, cosmetic preparations, etc. It can solve the problems of being unable to inhibit the escape of water molecules, achieve rich functions and styles, long-lasting activity, and slow down the loss of water.

Active Publication Date: 2017-11-21
YUNNAN XINYUN TECH DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention mainly aims at the problem that the existing capsule materials cannot suppress the escape of water molecules, and provides a three-layer water-containing capsule, and the present invention also provides a preparation method of the capsule

Method used

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  • Three-layer water-containing capsules and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The diameter of the capsule obtained in this example is about: 3.5-4.0mm, plum flavor, and its preparation method is as follows:

[0031] Preparation of aqueous core liquid layer: pure water, plum extract, propylene glycol, and sodium polyacrylate are uniformly mixed at a mass ratio of 8:1:1:0.01 to form an aqueous core material solution.

[0032] Preparation of phase-changeable grease layer: weigh palm oil and sucrose acetate isobutyrate according to a mass ratio of 5:1, mix them at 80°C and keep them warm for later use.

[0033] Preparation of natural animal and plant glue layer: Carrageenan, locust bean gum, guar gum, and starch are made into a uniformly mixed powder at a mass ratio of 1:1:0.5:0.1. After continuous stirring, the mixture is evenly dispersed and dissolved in 80℃ water, and then added The propylene glycol is mixed uniformly, and the temperature is kept at 80°C. The mass ratio of the mixed powder, propylene glycol, and water is 1:5:70.

[0034] Drop molding: Put...

Embodiment 2

[0037] The diameter of the capsule obtained in this example is about 3.5-4.0 mm, and it has a coconut flavor. The preparation method is as follows:

[0038] Preparation of aqueous core liquid layer: Dissolve and mix purified water, propylene glycol, water-soluble coconut essence, and sodium polyacrylate at a weight ratio of 9:1:1:0.01 to form an aqueous core material solution.

[0039] Preparation of phase-changeable grease layer: Weigh coconut oil and insect white wax at a mass ratio of 5:1, mix them at 80℃ and keep them warm for later use.

[0040] Preparation of natural animal and plant glue layer: Carrageenan, locust bean gum, guar gum, and starch are made into a uniformly mixed powder at a mass ratio of 1:1:0.5:0.1, and after constant stirring, evenly dispersed in 80 ℃ water, then add propylene glycol Mix well and keep warm at 80°C. The mass ratio of the mixed powder, propylene glycol, and water is 1:5:70.

[0041] Drop molding: Put the prepared water-containing core liquid layer...

Embodiment 3

[0044] The diameter of the capsule in this example is about 4.0-4.5mm, cocoa flavor, and its preparation method is as follows:

[0045] Preparation of aqueous core liquid layer: Dissolve and mix purified water, cocoa extract, and propylene glycol at a weight ratio of 9:1:1 to form an aqueous core material solution.

[0046] Preparation of phase-changeable grease layer: Weigh palm kernel oil, cocoa butter substitute and sucrose acetate isobutyrate according to a mass ratio of 1:2:1, and mix them at 80°C and keep them warm for later use.

[0047] Preparation of natural animal and plant glue layer: Carrageenan, locust bean gum, guar gum and starch are made into a uniformly mixed powder at a mass ratio of 1:1:0.5:0.1, and after constant stirring, evenly dispersed in 80 ℃ water, and then add propylene glycol Mix well and keep warm at 80°C, where the mass ratio of the mixed powder, propylene glycol, and water is 1:4.5:70.

[0048] Drop molding: Put the prepared water-containing core liquid ...

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Abstract

The invention discloses three-layer water-containing capsules and a preparation method thereof. The capsules consist of an inner layer, a middle layer and an outer layer, wherein the inner layer is a water-containing core liquid layer, the middle layer is a phase-changeable fat layer and the outer layer is a natural animal and plant glue layer. The preparation method comprises the following steps of through three-channel concentric circle drippers, simultaneously dipping out water-containing core liquid layer components, phase-changeable fat layer components and natural animal and plant glue layer components, which are blended, wherein the water-containing core liquid layer components are added to the inside channel, the natural animal and plant layer components are added to the outside channel, the phase-changeable fat layer components are added to the middle channel, and under the action of liquid cohesion of three sets of feed liquid, three concentric spheres which are in layer-in-layer nesting in cooling fluid fall down, and gradually cool and solidify, so that intact inclusion three-layer capsules are formed. The middle fat layer is introduced, so that water-containing core liquid can be effectively sealed, and besides, functional oil-soluble additives can be added to the middle fat layer as needed. Besides, the three-layer water-containing capsules have functions of oil capsules and water capsules.

Description

Technical field [0001] The invention belongs to the field of water-containing capsules, and specifically relates to a three-layer water-containing capsule and a preparation method thereof. Background technique [0002] Soft capsules, also known as capsules, are round or oval preparations made by confining oils or liquid medicines or suspensions that do not dissolve gelatin and other capsule materials in soft capsules. Compared with traditional capsules, soft capsules have distinct characteristics and wide adaptability. They are extremely transparent, have good heat resistance, moisture resistance, airtightness and toughness. They are widely used in tobacco, food, medicine, cosmetics and other industries. use. With the continuous advancement of human needs, the core liquid packaged in the capsule has far exceeded the oil-soluble substances, and expanded to the water-soluble liquid substances. Since the water-soluble core liquid capsule has the characteristics of easy absorption,...

Claims

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Application Information

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IPC IPC(8): A23P10/35A61K9/48A61K47/46A61K47/10A61K47/32A61K47/44A61K47/26A61K47/22A61K47/36A61K8/11A61Q19/00A24D3/06
Inventor 孙文轩林志文李敏黄吉
Owner YUNNAN XINYUN TECH DEV CO LTD
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