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A kind of three-layer water-containing capsule and preparation method thereof

A technology for water-containing capsules and capsules, applied in the directions of capsule delivery, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve problems such as the inability to inhibit the escape of water molecules, achieve rich functions and styles, slow down the loss of water, and have long-lasting activity. Effect

Active Publication Date: 2019-10-25
YUNNAN XINYUN TECH DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention mainly aims at the problem that the existing capsule materials cannot suppress the escape of water molecules, and provides a three-layer water-containing capsule, and the present invention also provides a preparation method of the capsule

Method used

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  • A kind of three-layer water-containing capsule and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The capsule diameter that obtains in the present embodiment is about: 3.5-4.0mm, plum flavor, and its preparation method is as follows:

[0031] Preparation of aqueous core liquid layer: uniformly mix purified water, plum extract, propylene glycol, and sodium polyacrylate at a mass ratio of 8:1:1:0.01 to form an aqueous core material solution.

[0032] Preparation of phase-change oil layer: weigh palm oil and sucrose acetate isobutyrate at a mass ratio of 5:1, mix well at 80°C and keep warm for use.

[0033]Preparation of natural animal and plant glue layer: mix carrageenan, locust bean gum, guar gum, and starch into a uniformly mixed powder at a mass ratio of 1:1:0.5:0.1, stir and dissolve evenly in 80°C water, then add Mix the propylene glycol and keep warm at 80°C, wherein the mass ratio of the mixed powder, propylene glycol and water is 1:5:70.

[0034] Dropping molding: put the prepared water-containing core liquid layer components, phase-changeable oil layer comp...

Embodiment 2

[0037] The capsule diameter that obtains in the present embodiment is about: 3.5-4.0mm, is coconut flavor, and its preparation method is as follows:

[0038] Preparation of aqueous core liquid layer: Dissolve and mix purified water, propylene glycol, water-soluble coconut essence, and sodium polyacrylate at a weight ratio of 9:1:1:0.01 to form an aqueous core material solution.

[0039] Preparation of phase-change oil layer: weigh coconut oil and white wax according to the mass ratio of 5:1, mix well at 80°C and keep warm for later use.

[0040] Preparation of natural animal and plant glue layer: mix carrageenan, locust bean gum, guar gum, and starch into a uniformly mixed powder at a mass ratio of 1:1:0.5:0.1, stir continuously and evenly disperse in water at 80°C, and then add propylene glycol Mix well and keep warm at 80°C, wherein the mass ratio of the mixed powder, propylene glycol and water is 1:5:70.

[0041] Dropping molding: put the prepared water-containing core liq...

Embodiment 3

[0044] The capsule diameter in the present embodiment is about: 4.0-4.5mm, cocoa flavor, and its preparation method is as follows:

[0045] Preparation of aqueous core liquid layer: Dissolve and mix purified water, cocoa extract, and propylene glycol at a weight ratio of 9:1:1 to form an aqueous core material solution.

[0046] Preparation of phase-change oil layer: weigh palm kernel oil, cocoa butter substitute and sucrose acetate isobutyrate in a mass ratio of 1:2:1, mix and keep warm at 80°C for use.

[0047] Preparation of natural animal and plant glue layer: mix carrageenan, locust bean gum, guar gum, and starch into a uniformly mixed powder at a mass ratio of 1:1:0.5:0.1, stir continuously and evenly disperse in water at 80°C, and then add propylene glycol Mix evenly and keep warm at 80°C, wherein the mass ratio of the mixed powder, propylene glycol and water is 1:4.5:70.

[0048] Dropping molding: put the prepared water-containing core liquid layer components, phase-ch...

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Abstract

The invention discloses three-layer water-containing capsules and a preparation method thereof. The capsules consist of an inner layer, a middle layer and an outer layer, wherein the inner layer is a water-containing core liquid layer, the middle layer is a phase-changeable fat layer and the outer layer is a natural animal and plant glue layer. The preparation method comprises the following steps of through three-channel concentric circle drippers, simultaneously dipping out water-containing core liquid layer components, phase-changeable fat layer components and natural animal and plant glue layer components, which are blended, wherein the water-containing core liquid layer components are added to the inside channel, the natural animal and plant layer components are added to the outside channel, the phase-changeable fat layer components are added to the middle channel, and under the action of liquid cohesion of three sets of feed liquid, three concentric spheres which are in layer-in-layer nesting in cooling fluid fall down, and gradually cool and solidify, so that intact inclusion three-layer capsules are formed. The middle fat layer is introduced, so that water-containing core liquid can be effectively sealed, and besides, functional oil-soluble additives can be added to the middle fat layer as needed. Besides, the three-layer water-containing capsules have functions of oil capsules and water capsules.

Description

technical field [0001] The invention belongs to the field of water-containing capsules, in particular to a three-layer water-containing capsule and a preparation method thereof. Background technique [0002] Soft capsules, also known as capsules, are round or oval preparations in which oils or liquid medicines or suspensions that have no dissolving effect on gelatin and other capsule materials are enclosed in soft capsules. Compared with traditional capsules, soft capsules have distinctive characteristics and wide adaptability. They have high transparency, good heat resistance, moisture resistance, sealing and toughness, and are widely used in tobacco, food, medicine, cosmetics and other industries. use. With the continuous improvement of human needs, the core fluid wrapped in capsules has far exceeded oil-soluble substances, and has expanded to water-soluble liquid substances. Since water-soluble core liquid capsules are easy to absorb, convenient to take, and can be adde...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23P10/35A61K9/48A61K47/46A61K47/10A61K47/32A61K47/44A61K47/26A61K47/22A61K47/36A61K8/11A61Q19/00A24D3/06
CPCA23P10/35A23V2002/00A24D3/061A61K8/11A61K9/4816A61K47/10A61K47/22A61K47/26A61K47/32A61K47/36A61K47/44A61K47/46A61K2800/10A61K2800/56A61Q19/00A23V2200/224A23V2200/10
Inventor 孙文轩林志文李敏黄吉
Owner YUNNAN XINYUN TECH DEV CO LTD
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