Method for preparation of methyl glycolate and by-product methyl methoxyacetate with catalyst

Abstract

Relating to a preparation method of chemical raw materials, the invention provides a method for preparation of methyl glycolate and by-product methyl methoxyacetate with a catalyst. The method adopts methylal as the solvent, s-trioxane, tetrameric or paraformaldehyde and methylal are taken as the source of formaldehyde, H2SO4, HCl and other liquid acids or cation exchange resin, heteropoly acid, impregnation solid acid, solid super acid and other solid acids are employed as the catalyst, one-step synthesis with high conversion rate and high selectivity is carried out to obtain methyl glycolate and the by-product methyl methoxyacetate. In a fixed bed reactor, 300g of an NKC-9 sulfonic acid resin catalyst is used, the raw materials include: 20kg of methylal, 4kg of water and 2.9kg of s-trioxane, the mass space velocity of the raw materials is 30h<-1>, reaction is carried out under a reaction temperature of 130DEG C and a reaction pressure of 6.0MPa, the catalyst is stable without inactivation for 2000h, the methylal conversion rate is 89.83%, the product methyl glycolate has mass selectivity of 28.88%, the methyl methoxyacetate has mass selectivity of 67.68%. The method provided by the invention has the advantages of short synthetic route, high raw material conversion rate or high product selectivity, and the synthesis process has no pollution to the environment.

Description

technical field [0001] The invention relates to a method for preparing methyl glycolate, in particular to a method for preparing methyl glycolate with a catalyst and producing methyl methoxyacetate by-product. Background technique [0002] Methyl glycolate (HOCH 2 COOCH 3 ), abbreviated as MG, is a colorless liquid with a pleasant smell, with a melting point of 74°C, a boiling point of 150°C, and a density of 1.168g / cm 3 , soluble in water, and soluble in alcohol and ether in any proportion. Methyl glycolate has α-H, hydroxyl and ester functional groups, so it has both the chemical properties of alcohols and esters, and can undergo carbonylation reactions, hydrolysis reactions, ammoniation reactions, oxidation reactions, etc. Methyl glycolate itself is an excellent solvent for many celluloses, resins and rubbers, and is easily soluble in nitrocellulose, cellulose acetate, polyvinyl acetate, etc. Methyl glycolate is also an important intermediate in organic synthesis and ...

AI Technical Summary

Problems solved by technology

A.T.Bell et al. used methyl formate instead of gaseous CO and formaldehyde for carbonylation reaction, but since the decomposition of methyl formate and release of CO is a rate-controlling step, it affects the performance of the catalytic reaction

[0028] In summary, the current synthetic methods of methyl glycolate all have problems such as too long synthetic route, low raw material conversion rate or low product selectivity, and environmental pollution during the synthetic process.

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