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Composition, and preparation method and application of composition

The technology of a composition and an extract is applied in the field of compositions with anti-acne efficacy and the preparation field thereof, which can solve the problems of aggravating skin damage, small side effects, smothering, etc. Effect

Inactive Publication Date: 2017-12-29
GUANGZHOU HUANYA COSMETIC SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, hormones and antibiotics are mainly used to treat acne. These drugs have an immediate effect on removing red, swollen and inflamed acne, but they cannot fundamentally cure acne. Long-term use will cause serious side effects and aggravate skin damage
Skin care products with anti-acne effects have fewer side effects than acne-reducing drugs, and are essential daily care products. However, most of the anti-acne products on the market are not very effective
[0004] CN 105902425 A discloses a mild facial cleanser for women, which includes plant essential oils and traditional Chinese medicine anti-acne ingredients, wherein rose essential oil or tea tree essential oil is mild and non-irritating, and the traditional Chinese medicine composition of gardenia, honeysuckle and witch hazel can effectively kill acne. Facial bacteria, however, this facial cleanser mainly has the effect of mild cleansing, not tight after washing, and has no significant therapeutic effect on acne
[0005] CN 106833973 A discloses a cold-process soap for removing acne and its preparation method. The cold-process soap is extracted from camellia comfrey oil, camellia oil, sweet almond oil, grape seed oil, rice bran oil, coconut oil, sodium hydroxide, Purified water, Ruyi Jinhuang Powder, traditional Chinese medicine extracts and plant essential oils are prepared in a certain proportion. It has the functions of cleaning the skin, controlling oil and removing acne, but has no nourishing effect

Method used

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  • Composition, and preparation method and application of composition
  • Composition, and preparation method and application of composition
  • Composition, and preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Embodiment 1 composition (I)

[0077] The formula is shown in Table 1.

[0078] Table 1

[0079]

[0080] Preparation:

[0081] Grind the raw materials of the Chinese medicine extract, mix them evenly after passing through a 100-mesh sieve, place them in a high-pressure homogenizer, add 50% ethanol according to the mass ratio of material to liquid at 1:30, and extract for 20 minutes under high-pressure homogenization at an extraction pressure of 20 MPa. After centrifugation, filter with a 200nm ceramic membrane, concentrate to 15% of the original volume with a reverse osmosis membrane at a pressure of 20 bar, and purify on a macroporous resin column with a resin model of D101, and use a 50% aqueous ethanol solution Elute until colorless, collect the eluate, decolorize with 8% (w / v) activated carbon, filter with a micropore with a pore size of 200nm, concentrate the filtrate to a mass ratio of 1:3 with the raw material of the traditional Chinese medicine composition...

Embodiment 2

[0082] Embodiment 2 composition (II)

[0083] The formula is shown in Table 2.

[0084] Table 2

[0085]

[0086] Preparation:

[0087] Grind the raw materials of the Chinese medicine extract, pass through a 150-mesh sieve, mix evenly, place in a high-pressure homogenizer, add 80% ethanol according to the mass ratio of material to liquid at 1:30, and extract for 25 minutes under high-pressure homogeneous extraction with an extraction pressure of 20 MPa. After centrifugation, filter with a ceramic membrane of 350nm, concentrate to 15% of the original volume with a reverse osmosis membrane under a pressure of 25 bar, and purify with a macroporous resin column of AB-8 with a concentration of 50%. The ethanol aqueous solution was eluted to colorless, and the eluate was collected, decolorized with 8% (w / v) activated carbon, filtered through a micropore with a pore size of 350nm, and the filtrate was concentrated to a mass ratio of 1:3 with the raw material of the traditional C...

Embodiment 3

[0088] Embodiment 3 composition (III)

[0089] The formula is shown in Table 3.

[0090] table 3

[0091]

[0092] Preparation:

[0093] Grind the raw materials of the Chinese medicine extract, pass through an 80-mesh sieve, mix evenly, place in a high-pressure homogenizer, add 30% ethanol according to the mass ratio of material to liquid at 1:20, and extract for 10 minutes under high-pressure homogenization at an extraction pressure of 30 MPa. After centrifugation, filter with a 50nm ceramic membrane, concentrate to 10% of the original volume with a reverse osmosis membrane at a pressure of 5 bar, and purify on a macroporous resin column with a resin model of D101, and use a 20% aqueous ethanol solution Elute until colorless, collect the eluent, decolorize with 5% (w / v) activated carbon, filter with a micropore with a pore size of 50nm, concentrate the filtrate to a mass ratio of 1:2 with the raw material of the traditional Chinese medicine composition, and vacuum at 70°...

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Abstract

The invention provides a composition, and a preparation method and an application of the composition. The composition is mainly prepared from the following raw materials in percentage by mass: 86-99% of a traditional Chinese medicine extract, 0.01-2% of plant essential oil and 0.9-12% of tween. The composition is reasonable in formula; the traditional Chinese medicine extract and the plant essential oil have a synergetic effect; the composition has effects of removing acne, repairing pockmarks and inhibiting acne recurrence; a prepared acne removing skin care product comprehensively prevents and treats the acne on aspects of bacterial inhibition, heat clearing, detoxicating, stasis removing, deep permeation and the like.

Description

technical field [0001] The invention belongs to the field of daily cosmetics, and relates to a composition and its preparation method and application, in particular to a composition with anti-acne effect, its preparation method and application. Background technique [0002] Acne, also known as acne, is prone to occur in adolescents and is a chronic inflammation of the pilosebaceous glands. Symptoms such as pain, inflammation and infection in severe cases, and even scars, have a great psychological and social impact on adolescents. One of the important factors that cause acne is that microorganisms such as Propionibacterium acnes produce lipolytic enzymes in the process of proliferation and reproduction, decompose sebum to produce free acid, cause damage to the hair follicle wall, and allow the accumulated sebum to enter the surrounding dermal tissue, resulting in inflammatory papules and even cyst. [0003] At present, hormones and antibiotics are mainly used to treat acne...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/92A61K8/49A61Q17/00A61Q19/00A61P31/04A61P17/10
Inventor 张怡龚盛昭胡兴国
Owner GUANGZHOU HUANYA COSMETIC SCI & TECH CO LTD
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