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Submicron emulsion repairing stock solution composition and preparation method thereof as well as cosmetic composition containing submicron emulsion repairing stock solution composition

A technology of sub-microemulsion and composition, which is applied in the directions of cosmetics, cosmetic preparations, drug combinations, etc., can solve problems such as skin problems that cannot be fundamentally solved

Active Publication Date: 2018-02-06
山东千色生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional cosmetics play the role of external modification and cannot fundamentally solve skin problems, while the application of EGF in beauty cosmetics is based on the physiological structure of human skin to repair and adjust cells at the molecular level

Method used

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  • Submicron emulsion repairing stock solution composition and preparation method thereof as well as cosmetic composition containing submicron emulsion repairing stock solution composition
  • Submicron emulsion repairing stock solution composition and preparation method thereof as well as cosmetic composition containing submicron emulsion repairing stock solution composition
  • Submicron emulsion repairing stock solution composition and preparation method thereof as well as cosmetic composition containing submicron emulsion repairing stock solution composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] Embodiment 1 A kind of preparation of submicron emulsion repair stock solution composition

[0079] The invention provides a method for preparing a submicron emulsion repair stock solution composition, the mass percentage of each component is as follows:

[0080]

[0081] Mix hyaluronic acid, hydroxyethylcellulose, propylene glycol / bis(hydroxymethyl)imidazolidinyl urea / methylparaben / iodopropynyl butylcarbamate with appropriate amount of ultrapure water in the prescribed amount Mix and dissolve in glycerin to obtain the water phase; mix mink oil, lecithin, and glyceryl monostearate, heat to 70°C, and cool to 40°C after completely dissolving to obtain the oil phase; stir at room temperature (300 rpm) to Add the water phase to the oil phase continuously at a rate of 0.5ml / min. After the emulsification is complete, add fatty alcohol polyoxyethylene ether and OSA modified starch dissolved in an appropriate amount of water, stir evenly, and obtain submicron Milk: Add olig...

Embodiment 2

[0085] Embodiment 2 Preparation of a kind of submicron emulsion repair stock solution composition

[0086] The invention provides a method for preparing a submicron emulsion repair stock solution composition, the mass percentage of each component is as follows:

[0087]

[0088]

[0089] Mix hyaluronic acid, DH-08, propylene glycol / bis(hydroxymethyl)imidazolidinyl urea / methylparaben / iodopropynyl butylcarbamate with appropriate amount of ultrapure water in glycerin in the prescribed amount Mix and dissolve to obtain a water phase; mix mink oil, soybean lecithin, and polysorbate, heat to 70°C, cool to 40°C after completely dissolving to obtain an oil phase; stir at room temperature (300 rpm) at 0.5ml / min Continuously add the water phase to the oil phase at a constant rate. After the emulsification is complete, add PEG-20, fatty alcohol polyoxyethylene ether and OSA modified starch dissolved in an appropriate amount of water. Stir evenly and obtain submicron Milk: Add olig...

Embodiment 3

[0091] Embodiment 3 Preparation of a kind of submicron emulsion repair stock solution composition

[0092] The invention provides a method for preparing a submicron emulsion repair stock solution composition, the mass percentage of each component is as follows:

[0093]

[0094]

[0095] Mix hyaluronic acid, hydroxyethyl cellulose, propylene glycol / bis(hydroxymethyl)imidazolidinyl urea / methylparaben / iodopropynyl butyl carbamate with appropriate amount of ultrapure water according to the prescribed amount Obtain the water phase; completely dissolve lecithin in ethanol, add isopropyl myristate and stir continuously on a magnetic stirrer until the system is fully uniform to obtain the oil phase; add the water phase to the oil phase under stirring conditions for emulsification The milky mixture is completely obtained, and then the oligopeptide-1, oligopeptide-3, and Cathelicidin-BF are mixed with the obtained milky mixture evenly and passed through a high-pressure micro-flui...

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Abstract

The invention relates to a preparation method of a submicron emulsion repairing stock solution composition and a cosmetic composition containing the submicron emulsion repairing stock solution composition. The submicron emulsion repairing stock solution composition is prepared from oligopeptide-3, oligopeptide-1, Indolicidin or an analogue thereof, Cathelicidin-BF, hyaluronic acid, glycerol, minkoil, lecithin, starch sodium octenylsuccinate, fatty alcohol polyoxyethylene ether, hydroxyethyl cellulose, propylene glycol / bis(hydroxymethyl)imidazolidinyl urea / methylparaben / iodopropynyl butylcarbamate and the like. A submicron emulsion repairing stock solution has the effects of keeping moisture and repairing, resisting bacteria and removing acnes. The repairing stock solution composition canbe used for promoting growth and cracking of various cells in epidermal tissues, promoting the growth of collagen, repairing aged collagen elastic fibers and recovering skin activity; especially, thesubmicron emulsion repairing stock solution composition has remarkable repairing effects on various epidermal wounds including acne marks, phototherapy, scalds and the like.

Description

technical field [0001] The invention belongs to the field of cosmetics. Specifically, the present invention relates to a submicron emulsion repair stock solution composition, its preparation method and the cosmetic composition containing it. Repairing aging collagen elastic fibers, restoring skin vitality, especially cosmetics or skin care products for repairing various epidermal wounds such as acne marks, phototherapy, and burns, and a preparation method thereof. Background technique [0002] Protein is the main component of human skin and one of the most important components of the human body. In the process of life, proteins are constantly synthesized, aged and die, and need to be supplemented continuously. Amino acids and peptides are the basic constituent units and structural parts of proteins. Therefore, the protein needs of the skin and the body can be quickly met by supplementing them. [0003] Human skin is mainly composed of epidermis and dermis. The main compon...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/73A61K8/64A61K8/55A61K8/06A61Q17/00A61Q19/00A61P17/10
CPCA61Q17/005A61Q19/00A61K8/06A61K8/553A61K8/64A61K8/735A61K8/922A61K8/925A61K2800/412Y02A50/30
Inventor 黄亚东张谷春项琪张谷敏肖巧学何金莲朱德勇
Owner 山东千色生物科技有限公司
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