Method for synthesizing aromatic alkyl ether

Abstract

The invention belongs to the technical field of chemical engineering and particularly discloses a method for synthesizing aromatic alkyl ether (Ar-O-R). The method comprises the following steps: taking aromatic phenol, a strong alkaline solution and alkyl sulphate as raw materials; carrying out high-speed mixing, high-temperature reaction, pH regulation, liquid phase separation, oil phase alkali wash, water phase alkali adding distillation and the like, thus finishing synthesis of asymmetric aromatic alkyl ether. Compared with a traditional synthesis method, the method disclosed by the invention has the advantages that reaction time is greatly shortened; the utilization rate of sulfate is high; and by adopting a material circular technology, the utilization rate of the aromatic phenol canreach 100 percent, and the purity of a product can reach 99 percent or above.

Description

technical field [0001] The invention belongs to the technical field of chemical production, and in particular relates to a method for synthesizing aryl alkyl ethers. Background technique [0002] Anisole, methyl anisole, phenetole and other substances (simplified molecular formula: Ar-O-R, where Ar is an aromatic group and R is an alkyl group) are important dyes, flame retardants and pharmaceutical intermediates, often used in in the process of organic synthesis. In industrial production, such substances can be obtained by reacting phenol and alkyl sulfate under alkaline conditions, and the basic principle of the reaction is shown in the following formula. [0003] [0004] where R 1 for H, CH 3 、C 2 h 5 , (CH 3 ) 2 , Cl, Br, etc.; R 2 for CH 3 、C 2 h 5 ; M is Na, K, NH 4 . Because alkyl sulfate is very easy to hydrolyze under alkaline conditions, the traditional view is that the reaction needs to be carried out by slowly adding reactants dropwise to the reac...

AI Technical Summary

Problems solved by technology

Although the reaction is strictly controlled under low temperature conditions, the hydrolysis of dimethyl sulfate is inevitable in the actual operation process, so the consumption of dimethyl sulfate is generally 1.2-1.4 times that of phenol

More importantly, the activity of the reactants is low at low temperature, so the reaction often takes 10-20 hours to complete, the production efficiency is seriously low, and the low-temperature refrigeration process also causes a large amount of energy consumption

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