Copper oxide-doped potassium-sodium niobate antibacterial piezoelectric ceramic implant as well as preparation and application of implant

Abstract

The invention belongs to the technical field of antibacterial implant materials, and discloses a copper oxide-doped potassium-sodium niobate antibacterial piezoelectric ceramic implant as well as preparation and application of the implant. The method comprises the following steps: (1) adding a solvent, niobium pentoxide, sodium carbonate and potassium carbonate into a ball milling device for ballmilling, standing, drying, calcining, and grinding into powder, to obtain potassium-sodium niobate precursor powder; (2) adding a solvent, copper oxide and the potassium-sodium niobate precursor powder into the ball milling device for ball milling, standing, drying, and calcining, to obtain copper oxide-doped potassium-sodium niobate ceramic powder; (3) evenly mixing the copper oxide-doped potassium-sodium niobate ceramic powder with a binder, granulating, forming, discharging glue, performing dense sintering, to obtain a ceramic sheet; and (4) polarizing the ceramic sheet, to obtain the copper oxide-doped potassium-sodium niobate antibacterial piezoelectric ceramic implant. The method is simple, and the prepared implant has a good antibacterial effect and stability.

Description

technical field [0001] The invention belongs to the technical field of preparation of antibacterial implant materials, in particular to a piezoelectric ceramic implant that utilizes the piezoelectric properties of the implant material itself and the metal copper ions released by it to achieve double-effect antibacterial purposes, and its preparation and application. application. Background technique [0002] Medical implants are widely used in bone repair, orthopedic surgery, and artificial dental implants, but implant infection is still a difficult clinical problem. During the implantation process, Staphylococcus aureus and Escherichia coli may cause orthopedic implant infection. Once implant infection occurs, it may cause local tissue destruction, inflammation, and implant failure. Repeated attacks of infection are difficult to control, resulting in recurrence. Surgery increases the mental and economic burden of patients, and increases the risk of reoperation. Therefore,...

AI Technical Summary

Problems solved by technology

Copper is usually added to the surface coating of medical materials to achieve antibacterial effect, but because the coating material is easy to fall off on ceramic-based materials, it is not conducive to processing and molding, which limits its clinical use

So far, no reports have been found about the dual-effect antibacterial materials that use copper and the piezoelectricity of the material itself and its use in antibacterial applications