Medical anticoagulation polymer material and preparation method thereof
A polymer material and anti-coagulation technology, which is applied in the field of medical materials, can solve the problems of cumbersome chemical treatment process, achieve the effect of improving anti-coagulation performance, simple preparation method, and remarkable anti-coagulation effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0038] Heparin azide was prepared into a 2mg / ml heparin azide solution with water, and then medical polyurethane film (thickness 1.0mm, size 1.0cm*1.0cm, aldrich, GF26918691-1EA) was soaked in heparin azide After 1 hour in the solution, the polymer material was taken out and dried at 50°C, irradiated with a UV lamp for 6 minutes (8w, 254nm), finally rinsed with distilled water, and dried at 50°C to obtain medical anticoagulant polyurethane.
[0039] The performance test of the medical anticoagulant polyurethane prepared by the present embodiment is as follows: Figure 1~4 shown. figure 1 It is the static water contact angle test chart of the anticoagulant polyurethane prepared in Example 1 (after treatment) and the unmodified polyurethane (before treatment); before the treatment, it is the unmodified polyurethane, and after the treatment, it is the anticoagulant polyurethane. From figure 1 The test results show that after heparin is grafted on the surface of the polyurethane...
Embodiment 2
[0044] Use water to prepare heparin azide into a 5mg / ml heparin azide solution, and then put a polyethylene terephthalate film (thickness 1.0mm, size 1.0cm*1.0cm, aldrich, model granular) Soak in heparin azide solution for 2 hours, then take out the film and dry it at 50°C, and irradiate it with an ultraviolet lamp (8w, 254nm) for 6min, and finally rinse it with distilled water, and dry it at 40°C to obtain medical anticoagulant polyparaphenylene Ethylene glycol dicarboxylate. The test results of the anticoagulant polyethylene terephthalate prepared in this example are similar to those in Example 1, and the anticoagulant performance of the modified material is greatly improved.
Embodiment 3
[0046] Use water to prepare heparin azide solution into a 10 mg / ml heparin azide solution, and then soak the polyethersulfone membrane (thickness 1.0mm, size 1.0cm*1.0cm, aldrich, pellets) in the heparin azide solution After 3 hours, the film was taken out and dried at 50°C, irradiated with ultraviolet light for 6 minutes, rinsed with distilled water, and dried at 70°C to obtain medical anticoagulant polyethersulfone. The test results of the anticoagulant polyethersulfone prepared in this example are similar to those in Example 1, and the anticoagulant performance of the modified material is greatly improved.
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More