Medical antimicrobial dressing and preparation method thereof

A technology of antibacterial agent and mixed components, applied in the field of medical supplies, can solve the problems of ineffective prevention of wound infection, unsatisfactory antibacterial effect, slow wound healing speed, etc., to promote rapid healing, prevent wound infection, and have good anti-inflammatory effect Effect

Inactive Publication Date: 2018-05-04
张立栋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, although the commonly used medical antibacterial dressings have antibacterial properties, they have disadvantages such as unsatisfactory antibacterial effect, slow wound healing, poor biocompatibility, and inability to effectively prevent wound infection. Therefore, it is necessary to develop a medical antibacterial dressing to meet the needs of use needs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A medical antibacterial dressing, its composition by weight: 55 parts of sodium carboxymethyl cellulose, 48 parts of sodium alginate, 20 parts of stearic acid, 12 parts of nano-titanium dioxide, 8 parts of sodium carbonate, 16 parts of polylactic acid, poly 10 parts of ethylene glycol, 3 parts of glycerin, 5 parts of mannose, 8 parts of sweet potato starch, 0.3 parts of antibacterial agent.

[0025] A kind of medical antibacterial dressing, its preparation method comprises the following steps:

[0026] a. Add sodium carboxymethyl cellulose, sodium alginate, nano-titanium dioxide and sodium carbonate to the mixing mixer, stir at a speed of 200r / min for 30min, and the resulting mixed components are set aside;

[0027] b. Add the mixed components obtained in step a into the reaction kettle, raise the temperature to 50°C, add polylactic acid and polyethylene glycol, raise the temperature to 65°C under the protection of an inert gas, stir for 30min, and then lower it to 45°C...

Embodiment 2

[0037] A medical antibacterial dressing, its composition by weight: 58 parts of sodium carboxymethyl cellulose, 45 parts of sodium alginate, 25 parts of stearic acid, 10 parts of nano-titanium dioxide, 9 parts of sodium carbonate, 15 parts of polylactic acid, poly 12 parts of ethylene glycol, 2 parts of glycerin, 6 parts of mannose, 7 parts of sweet potato starch, 1.3 parts of antibacterial agent.

[0038] A kind of medical antibacterial dressing, its preparation method comprises the following steps:

[0039] a. Add sodium carboxymethyl cellulose, sodium alginate, nano-titanium dioxide and sodium carbonate to the mixing mixer, stir at a speed of 260r / min for 34min, and the resulting mixed components are set aside;

[0040] b. Add the mixed components obtained in step a into the reaction kettle, raise the temperature to 52°C, add polylactic acid and polyethylene glycol, raise the temperature to 70°C under the protection of an inert gas, stir for 34min, and then lower it to 46°C...

Embodiment 3

[0050]A medical antibacterial dressing, its composition by weight: 62 parts of sodium carboxymethyl cellulose, 50 parts of sodium alginate, 30 parts of stearic acid, 14 parts of nano-titanium dioxide, 10 parts of sodium carbonate, 18 parts of polylactic acid, poly 13 parts of ethylene glycol, 6 parts of glycerin, 7 parts of mannose, 10 parts of sweet potato starch, 2.3 parts of antibacterial agent.

[0051] A kind of medical antibacterial dressing, its preparation method comprises the following steps:

[0052] a. Add sodium carboxymethyl cellulose, sodium alginate, nano-titanium dioxide and sodium carbonate to the mixing mixer, stir at a speed of 300r / min for 38min, and the resulting mixed components are ready for use;

[0053] b. Add the mixed components obtained in step a into the reaction kettle, raise the temperature to 58°C, add polylactic acid and polyethylene glycol, raise the temperature to 80°C under the protection of inert gas, stir for 38min, and then drop to 49°C ...

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PUM

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Abstract

The invention relates to the technical field of medical supplies, and in particular relates to a medical antimicrobial dressing and a preparation method of the medical antimicrobial dressing. The medical antimicrobial dressing is prepared from the following raw materials in parts by weight: 55-65 parts of sodium carboxymethyl cellulose, 45-50 parts of sodium alginate, 20-35 parts of stearic acid,10-14 parts of nanometer titania, 8-12 parts of sodium carbonate, 15-18 parts of polylactic acid, 10-15 parts of polyethylene glycol, 2-6 parts of glycerol, 5-8 parts of mannose, 7-10 parts of sweet potato starch, and 0.3-3.3 parts of an antimicrobial agent. The prepared antimicrobial dressing has good biocompatibility, can be gradually absorbed by the body, is good in hydrophility and moisture absorption, provides a suitable moist rehabilitation environment for the wound, is easy to remove, causes no adhesion to the wound, can promote the rapid heal of the surface of the wound, can regulate the immune system, can promote the heal of the surface of the wound, is good in inflammation-resisting effect, can effectively prevent wound infection, belongs to an excellent antimicrobial material used for the surface of the wound, is low price, and is wide in source.

Description

technical field [0001] The invention relates to the technical field of medical supplies, in particular to a medical antibacterial dressing and a preparation method thereof. Background technique [0002] Biomedical polymer materials are non-living polymer materials used for the diagnosis, treatment, repair or replacement of biological tissues or organs for physiological system diseases, and to enhance or restore their functions. In living matter, protein, muscle, cellulose, starch, and various biological enzymes are all polymer compounds. Therefore, the structure and physical and chemical properties of artificially synthesized polymer materials are closest to those of living organisms, and they are ideal biomedical materials. Polymer materials have the characteristics of rich sources, various varieties, easy storage, wide range of variable properties, and easy processing. [0003] Antibacterial concepts, technologies and products have been widely used in daily life. For medi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/26A61L15/20A61L15/18A61L15/46A61L15/44
CPCA61L15/28A61L15/18A61L15/20A61L15/26A61L15/44A61L15/46A61L2300/10A61L2300/102A61L2300/404A61L2300/41A61L2300/412A61L2300/45A61L2300/624C08L1/286C08L5/04C08L67/04C08L71/02C08L3/02
Inventor 张立栋
Owner 张立栋
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