Preparation method and application of a nano-gap controllable silicon-based array

Abstract

The invention discloses a preparation method of a silicon substrate array with nanometer gaps being controllable and application thereof. The preparation method comprises the steps that a silicon slice substrate single-layer polystyrene colloidal crystal array is prepared; etching is conducted on the silicon slice substrate single-layer polystyrene colloidal crystal array by adopting a reactive ion etching method, the single-layer polystyrene colloidal crystal array is removed after etching is completed, and a tapered silicon substrate array is prepared; and the tapered silicon substrate arrayis taken as a template, a layer of gold film with the thickness being 10-50nm is deposited on the surface of the template by adopting a physical deposition method, gold nanoballs are deposited and formed at the top of the tapered silicon substrate, the distances among the gold nanoballs are adjusted by controlling the deposition time, and the silicon substrate array with the nanometer gaps beingcontrollable is prepared by controlling the deposition time and adjusting the distances among the gold nanoballs. The silicon substrate array is large in structure area, clean on surface, high in sensitivity and good in detection performance, can directly serve as a substrate material which has long-term stability and a high-activity surface enhanced Raman effect, and can be used for conducting rapid trace detection on the concentration of saccharin sodium salt. The preparation method is simple, convenient to operate, low in cost and economical and environmentally friendly.

Description

technical field [0001] The invention relates to the field of nano-gap array materials, in particular to a method for preparing a silicon-controlled silicon-based nano-gap (nanogap) array and its application. Background technique [0002] Sodium saccharin is a commonly used synthetic sweetener with the longest history and the most controversial in the food industry. It is widely used in beverages, jellies, preserves, pastries and other food industries. Sodium saccharin has no nutritional value to the human body except that it causes a sweet feeling in the sense of taste. When eating too much saccharin sodium, it will affect the normal secretion of gastrointestinal digestive enzymes, reduce the absorption capacity of the small intestine, and cause loss of appetite. At the same time, it will also cause thrombocytopenia, causing symptoms such as acute bleeding, multiple organ damage, and even malignant poisoning. Moreover, sodium saccharin also has certain carcinogenicity. Long...

AI Technical Summary

Problems solved by technology

Utilizing the surface-enhanced Raman effect is expected to realize the rapid trace detection of the concentration of sodium saccharin, but the substrate materials that produce the surface-enhanced Raman effect in the prior art are mainly noble metal nanoparticles such as gold and silver. These noble metal nanoparticles not only The structure area is small, the repeatability is poor, the uniformity is poor, and the preparation method is complicated and the cost is high, so the application of the surface-enhanced Raman effect is largely limited

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