Water gel woundplast containing American cockroach active ingredients

A technology of Periplaneta americana and active ingredients, applied in the field of medical supplies, can solve the problems of poor waterproof performance of the substrate, poor elasticity, limited movement, and non-waterproof band-aids, etc., to achieve the effect of promoting skin healing, accelerating recovery, and accelerating wound healing

Inactive Publication Date: 2018-08-10
云南宁康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The daily band-aid preparation process mostly uses paper cloth as the carrier, and the base has poor waterproof performance and no high ductility. Among the users, most of the wounds are infected because the band-aid is not waterproof and the...

Method used

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  • Water gel woundplast containing American cockroach active ingredients
  • Water gel woundplast containing American cockroach active ingredients
  • Water gel woundplast containing American cockroach active ingredients

Examples

Experimental program
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Effect test

Embodiment 1

[0026] A hydrogel band-aid containing the active ingredient of Periplaneta americana, comprising a hydrogel layer and a high-elasticity base layer for healing and in contact with the skin, wherein:

[0027] The hydrogel layer is made of the following components by mass: 3 parts of Periplaneta americana extract, 1 part of Bletilla striata extract, 3 parts of chitosan hydrochloride, 4 parts of polyvinylpyrrolidone K30, 0.1 part of HPMC10W, PVA- 1 part of 17880, 3 parts of glycerin, 30 parts of pure water;

[0028] High elastic base layer is polyurethane film;

[0029] The Periplaneta americana extract is the alcoholic extract of the Periplaneta americana, which is prepared by the following method: the Periplaneta americana is soaked in ethanol three times, each soaking for 10 days, the ethanol mass concentration of each soaking is 95%, and the amount of ethanol is 0.5%. Periplaneta americana: filter after soaking each time, combine the filtrate three times and carry out convent...

Embodiment 2

[0040] A hydrogel band-aid containing the active ingredient of Periplaneta americana, comprising a hydrogel layer and a high-elasticity base layer for healing and in contact with the skin, wherein:

[0041] The hydrogel layer is made of the following components by mass: 2 parts of Periplaneta americana extract, 2 parts of Bletilla striata extract, 2 parts of chitosan hydrochloride, 2 parts of polyvinylpyrrolidone K30, 0.05 part of HPMC10W, PVA- 0.5 parts of 17880, 2 parts of glycerin, 25 parts of pure water;

[0042] High elastic base layer is polyurethane film;

[0043] The American cockroach extract is the American cockroach water extract, which is obtained by the following method: the dry Periplaneta americana is subjected to vacuum distillation and extraction three times according to the mass ratio of solid to liquid at 1:8, and is filtered after each extraction for 2 hours, and the filtrates are combined three times After , concentrating and drying, the aqueous extract o...

Embodiment 3

[0054] A hydrogel band-aid containing the active ingredient of Periplaneta americana, comprising a hydrogel layer and a high-elasticity base layer for healing and in contact with the skin, wherein:

[0055] The hydrogel layer is made of the following components by mass: 1 part of Periplaneta americana extract, 2 parts of Bletilla striata extract, 1 part of chitosan hydrochloride, 2 parts of polyvinylpyrrolidone K30, 0.08 part of HPMC 10W, PVA 1.5 parts of -17880, 3 parts of glycerin, 20 parts of pure water;

[0056] High elastic base layer is polyurethane film;

[0057] The Periplaneta americana extract is the alcoholic extract of the Periplaneta americana, which is prepared by the following method: the Periplaneta americana is soaked in ethanol three times, each soaking for 10 days, the ethanol mass concentration of each soaking is 95%, and the amount of ethanol is 0.5%. Periplaneta americana: filter after soaking each time, combine the filtrate three times and carry out con...

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Abstract

The invention provides water gel woundplast containing American cockroach active ingredients. The water gel woundplast comprises a water gel layer and a high-elasticity base body layer, wherein the water gel layer achieves a healing effect and is in contact with the skin. The water gel woundplast is characterized in that the water gel layer is prepared from the following ingredients in parts by mass: 1 to 3 parts of American cockroach extracts, 1 to 2 parts of bletilla extracts, 1 to 3 parts of chitosan hydrochloride, 1 to 4 parts of polyvinylpyrrolidone K30, 0.05 to 0.1 part of HPMC10W, 0.5 to 1.5 parts of PVA-17880, 1 to 3 parts of glycerol and 20 to 30 parts of pure water. In the contact process of the water gel woundplast with the skin, the water gel layer has the effects of inhibitingbacteria, diminishing swelling, relieving pain and prompting skin healing through the American cockroach extracts and the bletilla extracts; meanwhile, through the chitosan hydrochloride loaded withantibacterial materials with high biocompatibility, the antibacterial and bleeding stopping effects are further improved; the healing time is shortened; the medicine dwell time is prolonged; the wounded surface can better absorb the medicine; the skin tissue restoration is accelerated; the wound healing and regeneration rate is improved; meanwhile, the good waterproof effect and skin-friendly comfort are realized.

Description

technical field [0001] The invention belongs to the technical field of medical supplies, and in particular relates to a hydrogel band-aid containing an active ingredient of Periplaneta americana and a preparation method thereof. Background technique [0002] The American cockroach (Periplaneta americana L.) belongs to the class Insecta, the order Blatella, the suborder Blatella, and the genus Periplaneta. one. At present, scholars at home and abroad have more and more researches on Periplaneta americana, and found that it has anti-tumor, anti-virus, detumescence, repair, very significant anti-inflammatory activity, and good inflammation inhibition rate. [0003] Bletilla striata is the dry tuber of Bletilla striata, a common traditional Chinese medicine with high medicinal value. It has the functions of astringent and hemostasis, clearing away heat and dampness, reducing swelling and promoting muscle growth, antibacterial, promoting wound healing, and resisting chapped skin...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/24A61L15/42A61L15/44A61L15/46A61K36/898A61P17/02A61P31/02A61K35/64
CPCA61K36/898A61L15/24A61L15/28A61L15/42A61L15/44A61L15/46A61K35/63
Inventor 李映波李艳孙笠雯赵思聪
Owner 云南宁康生物科技有限公司
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