Traditional Chinese medicine membrane for treating foot rot and preparation method thereof

A technology for hoof rot and traditional Chinese medicine, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. accurate effect

Inactive Publication Date: 2018-09-28
广西南宁桂尔创环保科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the shortcomings of the single function of the medicine in the treatment of foot rot in the prior art, the present invention provides a multi-functional and fast-acting traditional Chinese medicine film for the treatment of foot rot

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] (1) According to the ratio of parts by weight, take 25 parts of water-soluble chitosan and dissolve it in 80 parts of distilled water. It is completely dispersed in it, and dried naturally after coating to obtain the drug film a;

[0032] (2) Take 15 parts of purslane powder, 15 parts of coptis powder, 20 parts of sesame oil and 10 parts of musk, mix them evenly, put them in a constant temperature water bath at 30°C, add 15 parts of emulsifier and 20 parts of distilled water, and then cut them at 4500rpm Cut emulsification, obtain emulsified bacteriostatic agent;

[0033] The emulsifier is formed by mixing Tween-80 and PEG400 according to the mass ratio of 1:1;

[0034] (3) Mix 40 parts of emulsifying antibacterial agent, 30 parts of oxygen-carrying microbubbles and 30 parts of acid-soluble chitosan according to the ratio of parts by weight, smear on the side of the drug film a, and obtain a composite double-layer drug after drying. membrane;

[0035] Described acid-...

Embodiment 2

[0044] (1) According to the ratio of parts by weight, take 30 parts of water-soluble chitosan and dissolve it in 81 parts of distilled water, add 25 parts of peppercorn kernel oil and mix evenly. It is completely dispersed in it, and dried naturally after coating to obtain the drug film a;

[0045] (2) Take 20 parts of purslane powder, 15 parts of coptis powder, 30 parts of sesame oil and 15 parts of musk, mix them evenly, put them in a constant temperature water bath at 30°C, add 15 parts of emulsifier and 20 parts of distilled water, and then cut them at 6000rpm Cut emulsification, obtain emulsified bacteriostatic agent;

[0046] Described emulsifying agent is formed by mixing Tween-80 and PEG400 according to the mass ratio of 1.5:1;

[0047] (3) Mix 60 parts of emulsified bacteriostatic agent, 30 parts of oxygen-carrying microbubbles and 10 parts of acid-soluble chitosan according to the ratio of parts by weight, smear on the side of the drug film a, and obtain a composite...

Embodiment 3

[0057] (1) According to the ratio of parts by weight, take 28 parts of water-soluble chitosan and dissolve them in 82 parts of distilled water. It is completely dispersed in it, and dried naturally after coating to obtain the drug film a;

[0058] (2) Take 18 parts of purslane powder, 18 parts of coptis powder, 24 parts of sesame oil and 12 parts of musk, mix them evenly, put them in a constant temperature water bath at 30°C, add 18 parts of emulsifier and 30 parts of distilled water, and then cut them at 5000rpm Cut emulsification, obtain emulsified bacteriostatic agent;

[0059] Described emulsifier is formed by mixing Tween-80 and PEG400 according to the mass ratio of 1.3:1;

[0060] (3) Mix 50 parts of emulsified bacteriostatic agent, 25 parts of oxygen-carrying microbubbles and 25 parts of acid-soluble chitosan according to the ratio of parts by weight, smear on the side of the drug film a, and obtain a composite double-layer drug after drying. membrane;

[0061] Descr...

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PUM

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Abstract

The invention provides a traditional Chinese medicine membrane for treating foot rot and a preparation method thereof. The traditional Chinese medicine membrane is prepared by, by weight, 30-60 partsof eucalyptus oil, 25-30 parts of water-soluble chitosan, 19-30 parts of aloe whole-leaf freeze-dried powder, 15-20 parts of purslane powder, 15-20 parts of rhizoma coptidis powder, 20-30 parts of sesame oil, 10-15 parts of musk, 20-25 parts of Zanthoxylum bungeanum Maxim seed oil, 10-30 parts of acid-soluble chitosan and 20-30 parts of oxygen-carrying microbubbles. The traditional Chinese medicine membrane and the preparation method have the advantages that the chitosan is used as the carrier to load antibacterial substances to prepare the compound double-layer traditional Chinese medicine membrane, the outermost eucalyptus oil of the membrane can change lipoid bilayer structures among stratum corneum cells to increase the disorder degree of the lipoid bilayer structures so as to promotedrug percutaneous penetration, and the microbubbles can inhibit anaerobic pathogenic bacteria such as fusobacterium necrophorum; the traditional Chinese medicine membrane is high in antibacterial rate, quick in action, capable of continuously releasing drugs, capable of curing the foot rot in a short time and good in effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, in particular to a pharmaceutical preparation for treating foot rot and a preparation method thereof. Background technique [0002] Foot rot, also known as (toe) cellulitis and laminitis, is a local suppuration mainly characterized by hoof horny corruption, interdigital skin and tissue corruption and suppuration caused by Fusobacterium necroptosis and Bacteroides throciens Sexual, necrotizing acute or subacute inflammation. Foot rot is one of the most harmful diseases among hoof diseases. Affected animals often have deformed hooves, false walking and landing on the ground, daring to lift but dare not step on, difficulty in moving, loss of appetite, and symptoms such as decreased lactation and reduced reproductive capacity. Acute critical cases or chronic cases often lead to the gradual weight loss of affected animals, shortening the use life, or even eliminating them. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/886A61K9/70A61K47/44A61K47/36A61K47/24A61P31/04A61P17/02A61K35/55
CPCA61K36/896A61K9/7015A61K35/55A61K36/185A61K36/31A61K36/718A61K36/758A61K36/886A61K47/24A61K47/36A61K47/44A61P17/02A61P31/04A61K2300/00
Inventor 戚海冰
Owner 广西南宁桂尔创环保科技有限公司
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