A kind of spiro ring aromatic fused ring imide compound and preparation method thereof
A spiro-aromatic fused-ring imide and a technology of fused-ring imide, which are applied in the field of new spiro-aromatic fused-ring imide compounds and their preparation, can solve the problem of increased synthesis difficulty, spiro-aromatic fused-ring acyl Imine compounds have not been developed and other problems, to achieve the effect of simple reaction conditions and high product yield
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Embodiment 1
[0044] Embodiment 1, the preparation of the compound of formula (I-1) Under the protection of nitrogen, add the perylene imide (778mg, 1mmol), 0.1mmol Palladium acetate, 5mmol sodium carbonate, 1mmol dibromomethane and 30ml dioxane, heated to 80°C, reacted for 8h, cooled to room temperature, poured the reaction solution into water, collected the precipitate by suction filtration, washed with water, dried, and purified by silica gel column , dichloromethane / petroleum ether as a developing solvent to obtain 623 mg of the compound of formula (I-1), yield: 80%. The reaction formula is as follows:
[0045]
[0046] Characterization data of formula (Ⅰ-1) compound ( Figure 1 to Figure 3 ):1 H NMR (400MHz, CDCl 3 ,300K)δ=8.81(dd,4H),8.73(d,4H),8.09(d,4H),5.20-5.12(m,4H),2.27(m,4H),2.15-2.13(m,4H) ,1.76(m,8H),1.23(m,48H),0.80(m,24H); 13 C NMR (100MHz, CDCl 3 ,273K):δ=165.36,164.42,164.17,163.30,141.83,138.73,135.07,133.35,132.56,129.70,127.56,126.70,124.98,124.79,124.08,123.84...
Embodiment 2
[0047] Embodiment 2, the preparation of formula (I-2) compound
[0048] Under nitrogen protection, in the 100ml two-necked bottle, add the perylene imide (664mg, 1mmol) that has monobromine substitution shown in formula (II-2), the palladium acetate of 0.1mmol, 5mmol sodium carbonate, 1mmol methylene bromide and 30ml Dioxane, heated to 80°C, reacted for 8h, cooled to room temperature, poured the reaction liquid into water, collected the precipitate by suction filtration, washed with water, dried, purified on a silica gel column, and used dichloromethane / petroleum ether as a developing solvent to obtain the formula (I-2) Compound 525mg, Yield: 79%. The reaction formula is as follows:
[0049]
[0050] Characterization data of formula (Ⅰ-2) compound ( Figure 4 to Figure 6 ): 1 H NMR (400MHz, CDCl 3 ,328.2K)δ=8.79(d,4H),8.71(d,4H),8.09(s,4H),5.21(m,4H),2.22(m,8H),1.79-1.72(m,8H), 1.36-1.25(m,16H),0.89(t,24H); 13 C NMR (100MHz, CDCl 3 ,328.2K):δ=165.73,164.81,163.74,142...
Embodiment 3
[0051] Embodiment 3, the preparation of formula (I '-1) compound
[0052] Under nitrogen protection, add monobromo-substituted condensed cyclic imide (900mg, 1mmol), 0.1mmol of palladium acetate, 5mmol of sodium carbonate, 1mmol of dibromomethane into a 100ml two-necked flask and 30ml of dioxane, heated to 80°C, reacted for 8h, cooled to room temperature, poured the reaction liquid into water, collected the precipitate by suction filtration, washed with water, dried, and purified by silica gel column, using dichloromethane / petroleum ether as developing solvent, 495 mg of the compound of formula (I'-1) was obtained, yield: 55%. The reaction formula is as follows:
[0053]
[0054] Characterization data of formula (I'-1) compound ( Figure 7 to Figure 9 ): 1 H NMR (500MHz, CDCl 2 CDCl 2 ,373K)δ=8.78-8.73(m,6H),8.67-8.62(m,6H),8.34-8.33(d,2H),8.20-8.18(d,4H),8.06(s,2H),5.10- 5.06(m,4H),2.17-2.12(m,8H),1.86-1.81(m,8H),1.28-1.18(m,80H),0.82-0.76(m,24H); 13 C NMR (125MHz, ...
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