Interbody fusion deVice based on 3D printing and preparation method of deVice

Abstract

The inVention discloses an interbody fusion deVice based on 3D printing and a preparation method of the deVice. By adopting polyaryletherketone series materials as basic raw materials, adopting a mixture of degradable high-molecular materials and actiVated osteogenesis powder as an auxiliary raw material and utilizing a dual-sprayer extrusion-type 3D printing technology, the interbody fusion deVice is prepared. The interbody fusion deVice is of a hollow three-dimensional through structure, wherein the Volume ratio of the basic raw materials to the auxiliary raw material is (1:0.01)-(1:1). Thesurface of the interbody fusion deVice is proVided with cell identification sites, and therefore the interbody fusion deVice is applicable to a micro enVironment for cell adhesion and new bone deposition, so that the combination capability between the interbody fusion deVice and new bones is improVed. MoreoVer, with degradation of the degradable high-molecular materials, spaces of porous structures can be formed, gradual growth of the new bones into the spaces is facilitated to achieVe close combination between the interbody fusion body and bone tissue, and loosening and displacement of the interbody fusion deVice cannot occur.

Description

technical field [0001] The invention relates to the field of biomedical technology, and more specifically, to a 3D printed intervertebral fusion device and a preparation method thereof. Background technique [0002] At present, my country's aging population is gradually deepening, and the spinal degenerative diseases it brings have become common and frequently-occurring diseases that plague human beings in today's society. Degenerative spondylosis leads to intervertebral disc herniation, vertebral segmental instability, and nerve root compression symptoms caused by osteophyte formation, which seriously affects the work and life of patients. Once medication and physical conservative treatment fail, surgical treatment is often the final choice. Many scholars divide the essence of modern spinal surgery into four parts: decompression, fusion, orthopedics, and internal fixation. Intervertebral fusion combined with internal fixation is an effective means of modern clinical treatm...

AI Technical Summary

Problems solved by technology

PEEK fusion cage has better mechanical properties, but because it is a biologically inert material, after implantation in the intervertebral space, the upper and lower vertebral bodies can only be connected by the bone graft in the cage cavity, and the fusion cage itself cannot form osseointegration with new bone. Easy to cause loosening and displacement in the later stage of implantation

At present, the domestic production mainly uses rods through machining and forming, while many foreign countries use thermoplastic processing and forming. The former causes waste of raw materials, and the latter's forming process is limited by molds, making it difficult to carry out structural improvements. Patient Profile Personalized

[0005] The existing fusion cage itself cannot form an osseointegration with the new bone, and it is easy to cause loosening and displacement problems in the later stage of implantation

The traditional molding process cannot modify the material during the molding process to improve its biological properties