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Biological dressing for preventing scar formation and preparation method thereof

A biological dressing and scar technology, applied in bandages, absorbent pads, medical science, etc., can solve the problems of scar prevention and reduction, severe itching, poor perspiration, etc., to prevent and reduce scar formation and promote healing. Effect

Active Publication Date: 2018-10-23
海南芬森医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The above inventions and their dressing products mainly focus on protecting the wound environment, promoting wound healing, and preventing wound infection. Although they have played a good role in wound treatment, they do not involve the prevention and reduction of scar formation. The formation of scars not only affects the appearance, but also causes symptoms such as poor perspiration and severe itching, causing great pain to patients

Method used

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  • Biological dressing for preventing scar formation and preparation method thereof
  • Biological dressing for preventing scar formation and preparation method thereof
  • Biological dressing for preventing scar formation and preparation method thereof

Examples

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Effect test

preparation example Construction

[0042] The preparation method of this biological dressing for preventing scar formation comprises the following steps:

[0043] 1) Pack the base material into the packaging material, sterilize, and set aside;

[0044] 2) mixing sodium hyaluronate with water, stirring and dissolving to obtain a sodium hyaluronate solution;

[0045] 3) mixing EGF, KGF, FGF, glycerin and water, and stirring evenly to obtain a growth factor solution;

[0046] 4) Mix the compound active peptide, hydroxyethyl cellulose, chitosan, phenoxyethanol, witch hazel extract, scutellaria baicalensis root extract, raspberry extract, Burnet elm extract, onion extract and water, and stir homogeneously, to obtain a composite active peptide solution;

[0047] 5) mixing sodium hyaluronate solution, growth factor solution and complex active peptide solution to obtain dressing medicament;

[0048] 6) Fill the dressing agent into the packaging material obtained in step 1), fully infiltrate, and obtain a biological ...

Embodiment 1

[0054] The preparation method of embodiment 1 biological dressing, comprises the following steps:

[0055] 1) Fold the non-woven fabric into an aluminum foil bag, sterilize it, and set it aside;

[0056] 2) Take 50g of sodium hyaluronate, add 1000mL of ultrapure water to mix, heat and stir to dissolve, and obtain a sodium hyaluronate solution;

[0057] 3) Mix 0.5gEGF, 0.25gKGF, 0.25gFGF, 100g glycerin and 1000mL ultrapure water, and stir evenly to obtain a growth factor solution;

[0058] 4) 50g composite active peptides (5g copper tripeptide-1, 20g palmitoyl tripeptide-5, 5g tetrapeptide-30, 5g pentapeptide-3, 5g pentapeptide-18, 5g hexapeptide-2, 5g nonapeptide -1), 20g hydroxyethyl cellulose, 15g chitosan, 20g phenoxyethanol, 5g witch hazel extract, 20g scutellaria root extract, 10g raspberry extract, 5g Burnet extract, 10g onion extract Mix with 8000mL ultrapure water and stir evenly to obtain a complex active peptide solution;

[0059] 5) mixing sodium hyaluronate solu...

Embodiment 2

[0062] The preparation method of embodiment 2 biological dressings, comprises the following steps:

[0063] 1) Fold the non-woven fabric into an aluminum foil bag, sterilize it, and set it aside;

[0064] 2) Take 50g of sodium hyaluronate, add 1000mL of ultrapure water to mix, heat and stir to dissolve, and obtain a sodium hyaluronate solution;

[0065] 3) Mix 0.5g EGF, 0.25gKGF, 100g glycerin and 1000mL ultrapure water, stir evenly to obtain a growth factor solution;

[0066] 4) 50g composite active peptide (5g copper tripeptide-1, 20g palmitoyl tetrapeptide-7, 10g acetyl tetrapeptide-9, 10g hexapeptide-10, 5g nonapeptide-1), 20g hydroxyethyl cellulose , 15g chitosan, 20g phenoxyethanol, 5g witch hazel extract, 20g scutellaria root extract, 10g raspberry extract, 5g Burnet extract, 10g onion extract and 8000mL ultrapure water, stir well, Obtain compound active peptide solution;

[0067] 5) mixing sodium hyaluronate solution, growth factor solution and complex active peptid...

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Abstract

The invention discloses biological dressing for preventing scar formation and a preparation method thereof. The biological dressing for preventing scar formation comprises a packing material, a base material and a dressing medicament. The dressing medicament is composed of the following raw materials: sodium hyaluronate, composite bioactive peptide, EGF, KGF, FGF, glycerin, hydroxyethyl cellulose,chitosan, phenoxyethanol, a Hamamelis Virginiana extract, a scutellaria baicalensis root extract, a raspberry extract, a garden burnet extract, an onion extract and water. Meanwhile, the invention also discloses a preparation method of the biological dressing for preventing scar formation. As the biological dressing for preventing scar formation contains hyaluronic acid, EGF, KGF, small molecularbioactive peptide and various plant extracts and other bioactive components, the biological dressing has effects of promoting healing and preventing and minimizing scar formation and can be used fortreatment and nursing of various body surface wounds and problem skin.

Description

technical field [0001] The invention relates to a biological dressing for preventing scar formation and a preparation method thereof. Background technique [0002] The repair of human skin damage is a complex physiological process. The speed of wound healing and the formation and proliferation of scars after healing have always been difficult problems for people. For this reason, people are trying to find ideal dressings, including good biocompatibility, control and absorption of wound exudate, preventing bacterial invasion and inhibiting bacterial growth and reproduction, protecting new tissues, accelerating wound healing, preventing and reducing scars , hemostatic analgesia, good mechanical properties, etc. But also do not have a kind of dressing can reach and satisfy above-mentioned requirement so far. [0003] With the development of molecular biology, the research on the application of biomaterials in medical dressings is increasing, and a lot of results have been obt...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44A61L15/40
CPCA61L15/28A61L15/40A61L15/44A61L2300/252A61L2300/30A61L2300/412A61L2300/45C08L5/08C08L1/284
Inventor 沈静飞
Owner 海南芬森医疗器械有限公司
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