A kind of skin care product for skin moisturizing and barrier repair and preparation method thereof

A skin care product and barrier technology, which is applied in the field of cosmetics to achieve the effects of increasing skin moisture content, increasing skin moisture content, and reducing transepidermal moisture loss

Active Publication Date: 2021-03-30
SHANGHAI DERMATOLOGY HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the application of the active components used in the present invention in skin barrier repair

Method used

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  • A kind of skin care product for skin moisturizing and barrier repair and preparation method thereof
  • A kind of skin care product for skin moisturizing and barrier repair and preparation method thereof
  • A kind of skin care product for skin moisturizing and barrier repair and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0060] Embodiment 1-3 is used for the preparation of the emulsifiable cream of skin moisturizing and barrier repair

[0061] 1 raw material

[0062] Table 1 embodiment 1-3 and comparative example 1 formula

[0063]

[0064]

[0065] 2 Preparation method

[0066] 2.1 Preparation of kelp extract

[0067] Take kelp decoction pieces, crush them into coarse powder, add 10 times of water, extract at 70°C, extract for 12 hours, extract 3 times; combine the 3 extracts, concentrate under reduced pressure to 0.25g / ml equivalent to decoction pieces; store at low temperature at 2°C After 12 hours, the precipitate was separated and removed, and the supernatant was vacuum-dried to obtain the kelp extract.

[0068] 2.2 Preparation of cream

[0069] (1) Take all ingredients in the oil phase except vitamin E, heat to 70-80°C, and melt;

[0070] (2) Take all the ingredients in the water phase except sodium hyaluronate, carbomer, marine fish skin collagen oligopeptide, and essence, ad...

Embodiment 4-6

[0074] Embodiment 4-6 is used for the preparation of the emulsion of skin moisturizing and barrier repair

[0075] 1 raw material

[0076] Table 2 embodiment 4-5 and comparative example 2-4 formula

[0077]

[0078]

[0079] 2 Preparation method

[0080] 2.1 Preparation of kelp extract

[0081] Take kelp decoction pieces, crush them into coarse powder, add 30 times of water, extract at 90°C, extract for 8 hours, extract 3 times; combine the 3 extracts, concentrate under reduced pressure to 0.25g / ml equivalent to decoction pieces; store at low temperature at 2°C After 12 hours, the precipitate was separated and removed, and the supernatant was vacuum-dried to obtain the kelp extract.

[0082] 2.2 Preparation of emulsion

[0083] (1) Take all ingredients in the oil phase except vitamin E, heat to 70-80°C, and melt;

[0084] (2) Take all the ingredients in the water phase except low-molecular-weight sodium hyaluronate, xanthan gum, carbomer, marine fish skin collagen o...

Embodiment 7

[0088] The skin irritation evaluation of embodiment 7 emulsion

[0089] Choose 8 New Zealand white rabbits. One day before the test, cut off the hair on both sides of the upper back of the tested animals, about 3cm x 3cm each on the left and right sides. The epidermis should not be damaged during this period, otherwise a spare rabbit was used. Take 0.5mL of the skin care products prepared in Example 1 and Example 4 and apply it directly on the skin on the right side to prevent the rabbit from shaking and losing the test substance, cover it with two layers of gauze and a layer of plastic sheet, then fix it with a bandage, The side skin was used as blank control. The closure test was used and the application time was 4 hours. After the test, wash the test area with clear water, and observe the skin reaction situation in 1, 24, 48 and 72 hours, and carry out the skin reaction score according to the skin irritation test in the "Hygienic Standard for Cosmetics (2007 Edition)", and...

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Abstract

The invention discloses a skin care product for skin moisturizing and barrier repairing. The skin care product contains the following components by mass: 0.15%-0.25% of marine fish skin collagen oligopeptide, 0.8%-1.2% of a kelp extract, and 0.04%-0.06% of low molecular weight sodium hyaluronate. The invention also discloses a preparation method of the skin care product. Tests prove that the skincare product provided by the invention has very ideal moisturizing and nutrition repairing effects, after continuous use, the facial skin sensitivity, erythema and other symptoms of subjects are obviously improved, the damaged skin barrier can be quickly and effectively repaired, and the moisture content of the skin is obviously increased. All the raw materials adopted by the skin care product provided by the invention are all natural extracts or conventional skin care product additives, the adding amounts of all the components also meet the conventional requirements of skin care product production, therefore the skin care product is safe and reliable after long-term use.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a skin care product for skin moisturizing and barrier repair and a preparation method thereof. Background technique [0002] The quality of the skin's moisturizing ability can reflect whether the skin barrier function is normal or not. The reduction of skin moisturizing ability leads to the decrease of skin barrier function, and the decrease of skin barrier function further reduces skin moisturizing ability, resulting in a vicious circle. Therefore, moisturizing is the basis and key of skin care. The decline of skin moisturizing function will lead to a variety of skin problems. It is the bottom layer of the skin care pyramid and the foundation of skin care. When the skin lacks water, cell metabolism and information transmission are affected, and even obstacles appear. The physiological structure of the skin changes, such as dryness, roughness, loss of luster, reduced elasticit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9711A61K8/65A61K8/73A61Q19/00
CPCA61K8/65A61K8/735A61Q19/00A61K8/9711
Inventor 陈中建朱全刚朱聪聪潘会君薛继竞江海平李纪平张红敏
Owner SHANGHAI DERMATOLOGY HOSPITAL
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