Application of traditional Chinese medicine composition to preparation of medicines used for treating diseases caused by herpes virus infection

A technology of herpes virus infection and composition, applied in the field of medicine, can solve problems such as unrecorded treatment effect of postherpetic neuralgia, undisclosed herpes zoster pharmacological activity, etc., achieves prevention and treatment of postherpetic neuralgia, shortens recovery time , the effect is obvious

Inactive Publication Date: 2018-12-07
CHONGQING TAIJI INDAL GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Authorized patent CN103079574B discloses a polyethylene glycol composition, wherein polyethylene glycol can be used alone as an active ingredient, or in combination with other active ingredients such as antiviral drugs, although the patent claims that the polyethylene glycol composition can treat Herpes labialis, herpes genitalis and herpes zoster, but only the pharmacological experiments of the polyethylene glycol composition for treating herpes zoster are described in the instructions, and the pharmacological activity of the composition for treating herpes zoster is not disclosed. It is well known in the art that oral Herpes and shingles are two different types of viral infections
[0006] Authorized patent CN100341532C discloses an external preparation for treating herpes, which uses extracts of Sophora flavescens, propolis, cortex moutan, and escutellaria to prepare the external preparation, but does not record the therapeutic effect of the external preparation on postherpetic neuralgia how

Method used

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  • Application of traditional Chinese medicine composition to preparation of medicines used for treating diseases caused by herpes virus infection
  • Application of traditional Chinese medicine composition to preparation of medicines used for treating diseases caused by herpes virus infection

Examples

Experimental program
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Embodiment 1

[0031] Atractylodes 80g, Chenpi 80g, Magnolia officinalis (made from ginger) 80g, Angelica dahurica 120g, Poria cocos 120g, Dabupi 120g, raw pinellia 80g, licorice extract 10g, patchouli oil 0.8ml, perilla leaf oil 0.4ml. Add 60% ethanol to extract Atractylodes atractylodes, tangerine peel, Angelica dahurica, Magnolia officinalis, filter, and set aside the filtrate; add water to boil Poria cocos and Dabupi, filter the decoction, and set aside the filtrate; Add 13.5 parts by weight of dried ginger, decoct with water, filter the decoction, and use the filtrate for later use; smash the licorice extract and boil it to dissolve; combine the above extracts, filter, and distill the filtrate to recover ethanol; add patchouli oil and perilla Leaf oil, mixed evenly, added water to 1025ml, adjusted pH to 5.8-6.2, left standing, filtered to obtain a clear solution, sterilized, and filled to obtain a solution.

Embodiment 2

[0033] Atractylodes 80g, Chenpi 80g, Magnolia officinalis (made from ginger) 80g, Angelica dahurica 120g, Poria cocos 120g, Dabupi 120g, raw pinellia 80g, licorice extract 10g, patchouli oil 0.8ml, perilla leaf oil 0.4ml. Add 60% ethanol to extract Atractylodes atractylodes, tangerine peel, Angelica dahurica, Magnolia officinalis, filter, and set aside the filtrate; add water to boil Poria cocos and Dabupi, filter the decoction, and set aside the filtrate; Add 13.5 parts by weight of dried ginger, decoct with water, filter the decoction, and use the filtrate for later use; smash the licorice extract and boil it; combine the above extracts, filter, and concentrate the filtrate to a thick paste with a relative density of 1.30-1.35; Take an appropriate amount of polyethylene glycol 60000, heat to melt, add patchouli oil, perilla leaf oil and the above-mentioned thick ointment, mix well, drop into pills, and coat with film to obtain drop pills.

Embodiment 3

[0035] Atractylodes 80g, Chenpi 80g, Magnolia officinalis (made from ginger) 80g, Angelica dahurica 120g, Poria cocos 120g, Dabupi 120g, raw pinellia 80g, licorice extract 10g, patchouli oil 0.8ml, perilla leaf oil 0.4ml. Add 60% ethanol to extract Atractylodes atractylodes, tangerine peel, Angelica dahurica, Magnolia officinalis, filter, and set aside the filtrate; add water to boil Poria cocos and Dabupi, filter the decoction, and set aside the filtrate; Add 13.5 parts by weight of dried ginger, decoct with water, filter the decoction, and use the filtrate for later use; crush the licorice extract and boil it to dissolve; combine the above extracts, filter, and concentrate the filtrate to an appropriate amount. Dissolve patchouli oil and perilla leaf oil with appropriate amount of ethanol. Combine the above solutions, mix well, adjust the ethanol content with appropriate amount of ethanol and water, and make the whole amount into 1025ml, let stand, filter, and fill to obtain...

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Abstract

The invention relates to the application of a traditional Chinese medicine composition to preparation of medicines used for treating diseases caused by herpes virus infection. A prescription for the traditional Chinese medicine composition comprises, 80 parts by weight of Rhizoma Atractylodis, 80 parts by weight of dried orange peel, 80 parts by weight of Cortex Magnolia, 120 parts by weight of dahurian angelica roots, 120 parts by weight of Poria cocos, 120 parts by weight of areca peel, 80 parts by weight of raw pinellia ternate, 10 parts by weight of Extractum Glycyrrhizae, 0.8 part by volume of patchouli oil and 0.4 part by volume of perilla leaf oil. The traditional Chinese medicine composition uses tradition traditional Chinese medicines as raw materials, has small toxic and side effect and obvious treatment effect on herpes zoster, and can prevent and treat postherpetic neuralgia. No matter in a systemic administration manner or a local administration manner, the traditional Chinese medicine composition has better effect compared with the common medicine acyclovir. The traditional Chinese medicine composition can shorten the curing time of herpes, helps patients to get rid of the shadow of disease as early as possible, and is beneficial for the physical and mental health of patients.

Description

[0001] The invention belongs to the field of medicine, and in particular relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating diseases caused by herpes viruses. Background technique [0002] Viral herpes (Herpes Simplex) is a viral skin disease caused by viral herpes virus. Divided into herpes simplex and herpes zoster, herpes zoster is an acute herpetic skin disease caused by varicella zoster virus (VZV). VZV is a common human a herpes virus, which is brick-shaped in shape, coated with a capsid on the outside, with a diameter of about 150-200nm and double-stranded DNA inside. VZV has two main proteases: DNA polymerase and thymidine kinase. DNA polymerase is necessary for DNA synthesis, which may be involved in the latency of the virus. The virus is highly neurotropic and humans are its only natural host. Chickenpox is the cause of the initial infection, at which point VZV multiplies in different organs, espec...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61P31/22A61P25/00
CPCA61K36/076A61K36/232A61K36/284A61K36/484A61K36/532A61K36/535A61K36/575A61K36/752A61K36/8888A61K36/889A61P25/00A61P31/22A61K2300/00
Inventor 白礼西秦少容金思岑卿玉玲陈康覃学
Owner CHONGQING TAIJI INDAL GROUP
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