Sensitized fiber optic SPR sensor based on graphene oxide and gold nanorods

Abstract

In order to solve the problem of low sensitivity of existing fiber optic SPR biosensors, the invention provides a sensitized fiber optic SPR sensor based on graphene oxide and gold nanorods. Accordingto the sensitized fiber optic SPR sensor based on the graphene oxide and the gold nanorods, the plasmon coupling effect between a plasma wave on the surface of a gold film and a local surface plasmawave on the surface of the gold nanorods is utilized to enhance the electric field strength. At the same time, the charge transfer between the gold film and the gold nanorods can be promoted by the graphene oxide, so that interactions between a surface plasma wave and a substance to be detected is enhanced, and the detection sensitivity is improved. In addition, the graphene oxide has excellent bio-sensing characteristics, biocompatibility, and a large specific surface area, can better measure biomass and chemical quantities. Compared to an ordinary fiber optic SPR sensor, the sensitized fiberoptic SPR sensor based on the graphene oxide and the gold nanorods has higher sensing sensitivity and chemical stability, real-time monitoring can be performed, the structure of the sensor is compact, thereby being able to widely applied in the fields of physics, chemistry, biology, medical care, food safety and the like.

Description

technical field [0001] The invention relates to the technical field of biosensors, in particular to SPR biosensors, in particular to an optical fiber SPR sensor based on graphene oxide and gold nanorods for sensitization. Background technique [0002] Optical fiber surface plasmon resonance (Surface Plasmon Resonance) exists on the interface between the metal film on the surface of the optical fiber and the external medium. When light is incident from an optically dense medium to an optically sparse medium, total reflection will occur, but some light still passes through the light Sparse medium forms evanescent waves. At the same time, when the metal is subjected to electromagnetic interference, the electron density distribution inside the metal will become uneven, which will cause collective oscillations of electrons, which are expressed in the form of waves, called plasma waves. When the evanescent wave resonates with the surface plasmon wave, the energy is transferred fro...

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem of low sensitivity of existing optical fiber SPR biosensors, the present invention proposes a fiber optic SPR sensor based on graphene oxide and gold nanorods for sensitization. The plasmon coupling effect between the localized surface plasmon waves on the surface enhances the electric field strength, and at the same time, graphene oxide can promote the charge transfer between the gold film and the gold nanorods, thereby enhancing the surface plasmon waves and the measured Interaction of substances to improve detection sensitivity

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