A multi-target disc-type lateral flow test paper chip and its laser cutting preparation method, use method, application and detection device
A laser cutting and multi-target technology, which is applied in the field of multi-target disc-type lateral flow test paper chips and its laser cutting preparation, can solve the problems of limited space for a single lateral flow test paper and the inability to detect targets, so as to facilitate integration and experimentation Result optimization, development of powerful, high-precision effects
Active Publication Date: 2021-08-13
XI AN JIAOTONG UNIV
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Problems solved by technology
This method has achieved simultaneous detection of multiple targets in many studies by means of multiple detection lines. However, at present, a single lateral flow test paper is used in the detection, and the space of a single lateral flow test paper is limited, so it cannot be targeted at More targets are detected, and cross-reaction between multiple targets cannot be avoided
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[0045] The present invention will be further described in detail below in conjunction with specific embodiments, which are explanations of the present invention rather than limitations.
[0046] see figure 1 , a multi-object dish type lateral flow test paper chip, including a circular hydrophobic substrate 1, a probe storage pad 3 is provided in the middle of the hydrophobic substrate 1, and several strips are provided along the circumference of the hydrophobic substrate 1 to communicate with the probe storage pad 3 The hydrophilic channel 2 of the hydrophobic substrate 1 is also provided with a water absorption area 4 capable of covering part of the hydrophilic channel 2 on the circumference of the hydrophobic substrate 1 .
[0047] The above-mentioned multi-object disc lateral flow test paper chip is made by laser cutting process, including the preparation of the hydrophobic substrate 1, the hydrophilic channel 2, the probe storage pad 3 and the water absorption area 4, and ...
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Abstract
The invention discloses a multi-target dish-type lateral flow test paper chip and its laser cutting preparation method, use method, application and detection device. Several hydrophilic channels connected to the probe storage pad are set on the circular hydrophobic substrate, which can achieve the purpose of simultaneous detection of multiple targets, and is more convenient for integration and optimization of experimental results; the number of channels and channels can be designed according to different detection requirements. The length and detection type, etc., can be developed with strong performance; the liquid flow is guided by capillary action, no additional fluid drive device is required, the biocompatibility is good, and the post-processing is simple. Design the size and shape of each area of the test paper chip according to the target test requirements to be tested, and use the laser cutting process to prepare the test paper chip, which is simple and fast, with short production cycle, low energy consumption, high precision and good repeatability. It can be used as a miniaturized and rapid on-site rapid detection device, especially in the fields of clinical diagnosis, food hygiene, environmental monitoring, biochemistry and the like, and has good application prospects.
Description
technical field [0001] The invention belongs to the technical fields of environment, food safety and biomedicine-related detection, and in particular relates to a multi-object disc lateral flow test paper chip and its laser cutting preparation method, use method, application and detection device. Background technique [0002] Fast, sensitive, and portable multi-target detection methods have attracted more and more attention in the fields of environmental monitoring, food safety, and biomedical testing. For example, toxic substances such as pathogens, heavy metal ions, and bacteria are important indicators for water quality evaluation; in addition, as one of the most concerned issues in global public health, foodborne diseases are often caused by different types of pollutants (such as bacteria, antibiotics, illegal Additives and pesticide residues) pollute food, which causes one tenth of the population to get sick every year; in addition, in disease detection, doctors usually...
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IPC IPC(8): G01N21/64B01L3/00B23K26/38B23K26/402
CPCB01L3/502707B23K26/38B23K26/402G01N21/6428
Inventor 林敏金碧瑞杨叶欣卢天健
Owner XI AN JIAOTONG UNIV