Tablet for treating prostatic uroschesis and preparation method and application thereof

A technology of Tongpian and LongBi, which is applied in the field of Qianlie LongBiTong Tablet and its preparation, can solve the problems of general product efficacy, unstable process, and inability to achieve ideal therapeutic effect, and achieve good therapeutic effect and curative effect. Good, better efficacy

Inactive Publication Date: 2019-02-19
SHANGHAI JINGFENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the production process, there are problems such as unstable process, general drug effect of the prepared product, and failure to achieve the desired therapeutic effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The specific preparation process of Qianlielongbutong Tablets is as follows:

[0035] 1. Weigh each raw material according to the following quality:

[0036] Astragalus 50g, ground beetle 90g, mallow fruit 20g, peach kernel 50g, cinnamon twig 20g, epimedium 40g, bupleurum 10g, poria cocos 100g, knotweed 30g, aurantium 40g, achyranthes bidentata 30g;

[0037] 2. Mixing and crushing:

[0038] Control the stirring rate of each component in the above formula under the condition of 50rad / min for mixing, and after the pulverizer is fully pulverized, sieve to obtain a powder of 50 mesh or more;

[0039] 3. Add water and decoct to extract:

[0040] Add water 15 times the total mass of all ingredients and decoct three times, the first time for 2 hours, the second and third times for 3 hours each, combine the decoction, filter, and concentrate the filtrate to a thick paste with a relative density of 1.10-1.20 (60°C);

[0041]4. Drying and tableting:

[0042] Dry the thick pas...

Embodiment 2

[0045] The specific preparation process of Qianlielongbutong Tablets is as follows:

[0046] 1. Weigh each raw material according to the following quality:

[0047] Astragalus 90g, Wood Beetle 50g, Mallow Fruit 40g, Peach Kernel 20g, Guizhi 40g, Epimedium 30g, Bupleurum 30g, Poria 50g, Polygonum cuspidatum 50g, Citrus aurantium 20g, Sichuan Achyranthes bidentata 50g;

[0048] 2. Mixing and crushing:

[0049] Control the stirring rate of each component in the above formula under the condition of 50rad / min for mixing, and after the pulverizer is fully pulverized, sieve to obtain a powder of 50 mesh or more;

[0050] 3. Add water and decoct to extract:

[0051] Add water 12 times the total mass of all ingredients and decoct twice at 90°C for 3 hours for the first time and 3 hours for the second time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.05-1.10 (60°C ) thick paste;

[0052] 4. Drying and tableting:

[0053] Dry the thick past...

Embodiment 3

[0056] The specific preparation process of Qianlielongbutong Tablets is as follows:

[0057] 1. Weigh each raw material according to the following quality:

[0058] Astragalus 60g, Wood Beetle 80g, Mallow Fruit 22g, Peach Kernel 40g, Guizhi 22g, Epimedium 39g, Bupleurum 12g, Poria 90g, Polygonum cuspidatum 35g, Citrus aurantium 22g, Sichuan Achyranthes bidentata 45g;

[0059] 2. Mixing and crushing:

[0060] Control the stirring rate of each component in the above formula under the condition of 50rad / min for mixing, and after the pulverizer is fully pulverized, sieve to obtain a powder of 60 mesh or more;

[0061] 3. Add water and decoct to extract:

[0062] Add water 14 times the total mass of all ingredients and decoct once. The decoction temperature is 95°C, and the decoction time is 7h. Combine the decoction, filter, and concentrate the filtrate to a thick paste with a relative density of 1.05-1.10 (60°C). ;

[0063] 4. Drying and tableting:

[0064] Dry the thick pas...

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PUM

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Abstract

The invention provides a tablet for treating prostatic uroschesis and a preparation method and application thereof. The tablet is mainly prepared from, by mass, 50 parts of radix astragali, 50-90 parts of ground beetles, 20-40 parts of fructus malvae vertillatae, 20-50 parts of peach kernels, 20-40 parts of cassia twigs, 30-40 parts of herba epimedii, 10-30 parts of radix bupleuri, 50-100 parts ofporia cocos, 30-50 parts of rhizoma polygoni cuspidati, 20-40 parts of rhizoma polygoni cuspidati and 30-50 parts of rhizoma polygoni cuspidati. The preparation method comprises the following steps of adding water for decoction 1-3 times, wherein the mass of the added water is 10-15 times greater than the total mass of all components, the total decoction time is 6-8 hours, and then the tablet canbe obtained. The tablet for treating prostatic uroschesis has a wide application range in uroschesis caused by kidney deficiency and blood stasis; according to the symptoms of uroschesis, patients may urinate frequently, slowly and difficultly, and urine cannot be discharged completely after urination every time; the tablet is widely applied in soreness and weakness of the waist and knees and other disease symptoms.

Description

technical field [0001] The present invention relates to the field of Qianlielongbutong tablet processing, in particular to a Qianlielongbutong tablet and its preparation method and application. Background technique [0002] Prostatic hyperplasia is a common male disease, and its incidence gradually increases with age. It is the main cause of voiding disorders in middle-aged and elderly male patients. There are many causes of benign prostatic hyperplasia, the main cause of which is the change of hormone levels in the human body with age, such as testosterone and dihydrotestosterone. The latter stimulates the proliferation of prostate gland tissue, which in turn causes LUTS represented by bladder outlet obstruction, and produces a series of lower urinary tract obstruction syndromes such as urinary retention and urinary tract infection. Symptoms such as exhaustion, intermittent urination, slow urination, weak urine stream, and thin and weak urine stream. [0003] For a long t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/20A61P13/08A61K35/64
CPCA61K9/20A61K35/64A61K36/076A61K36/185A61K36/21A61K36/233A61K36/296A61K36/481A61K36/54A61K36/704A61K36/736A61K36/752A61K2236/331A61K2236/39A61K35/63A61P13/08A61K2300/00
Inventor 薛亮钱正祥
Owner SHANGHAI JINGFENG PHARMA
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