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Heparinoid composition-containing spray

A composition and spray technology, applied in the field of sprays containing heparin-like compositions, can solve problems such as imperfect application of heparin-like compositions, and achieve inhibiting smooth muscle cell reproduction, promoting supply and waste excretion, and inhibiting excessive growth. Effect

Pending Publication Date: 2019-03-15
沈阳亿欣源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the prior art, the application of the heparinoid composition on the skin, mucous membrane and other action sites is not perfect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1: A spray containing a heparinoid composition, including 30 parts of heparin, 66.1 parts of purified water, 0.1 part of dimethyl sulfoxide, 0.1 part of vitamin C, 0.1 part of potassium sorbate, 3 parts of glycerin, 0.18 parts of preservatives.

Embodiment 2

[0024] Example 2: A spray containing a heparinoid composition, including 10 parts of heparin, 65.5 parts of purified water, 1 part of dimethyl sulfoxide, 0.125 parts of vitamin C, 0.125 parts of potassium sorbate, 10 parts of glycerin, Preservatives 2 parts.

Embodiment 3

[0025] Example 3: A spray containing a heparinoid composition, including 0.5 parts of heparin, 57.1 parts of purified water, 2 parts of dimethyl sulfoxide, 0.2 parts of vitamin C, 0.2 parts of potassium sorbate, 15 parts of glycerin, Preservatives 5 parts.

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PUM

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Abstract

The invention discloses a heparinoid composition-containing spray and belongs to the technical field of biology. The heparinoid composition-containing spray is characterized by comprising 0.01-30 parts of mucopolysaccharide, 30-90 parts of solvent, 0.01-5 parts of a transdermal absorbent, 0.01-5 parts of an antioxidant, 0.01-5 parts of a bacteriostatic agent, 0.01-5 parts of a surfactant, and 0.01-5 parts of a preservative. Under the synergistic effects of a cutin softener and a natural humectant, the excessive growth of a collagenous fiber is inhibited, the formation of a scar is alleviated;the moisture on the surface of the skin is retained, the collagenous fiber is softened, the elasticity is strengthened, and the heparinoid composition-containing spray has a softening effect on the hypertrophic scar.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a spray containing a heparin-like composition used in medicines, medical equipment, cosmetics, disinfection products and the like. Background technique [0002] Heparinoid is a mucopolysaccharide. In 1948, when Jorpes and Gardell prepared heparin from liver and lung, they obtained a polysaccharide composed of D-glucuronic acid and D-glucosamine. These substances are similar in structure to heparin , but the degree of sulfation is low, and the anticoagulant activity is low, but after more sulfation, its properties change greatly. By combining with the surface of vascular endothelium, it promotes the release of endogenous amino polysaccharides with antithrombotic activity, which can improve local microcirculation, increase blood flow and blood flow velocity, thereby improving intermediate metabolism, promoting skin nutrition supply and waste excretion , play a role in redu...

Claims

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Application Information

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IPC IPC(8): A61K9/12A61K31/727A61K31/737A61K47/42A61P7/10A61P9/14A61P17/02A61P29/00A61P31/02A61P31/04A61P31/10A61P31/14
CPCA61K9/0014A61K9/12A61K31/727A61K31/737A61K47/42A61P7/10A61P9/14A61P17/02A61P29/00A61P31/02A61P31/04A61P31/10A61P31/14
Inventor 唐财坤关云成李丹陈菲单颖满国荣朱凯月肖秀梅马立强
Owner 沈阳亿欣源生物科技有限公司
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