Hp infection-preventing composition for promoting balance of flora of stomach and application thereof

Abstract

The invention provides an Hp infection-preventing composition for promoting balance of flora of stomach and application thereof. The composition is prepared from the following components in parts by weight: 200-900 parts of mannan-oligosaccharide, 100-400 parts of large molecular weight chitosan oligosaccharide and 100-400 parts of chitosan. The composition resists Hp infection and promotes balance of flora of stomach synergically, and the using effect is improved obviously if the three components are used independently. The composition can maintain balance of flora of stomach effectively to prevent Hp infection for healthy crowds without Hp infection and stomach diseases. The composition can inhibit Hp obviously for a pure Hp infector without stomach diseases and can promote balance of flora of stomach at the same time and prevent concurrent stomach diseases of the patients effectively. The composition can inhibit Hp obviously for patients infected with Hp and with related stomach diseases and can adjust balance of flora of stomach, so that further development of stomach diseases is avoided effectively, the clinical symptoms are improved, and the living quality of the patients isimproved.

Description

technical field [0001] 1. The present invention belongs to the field of medical and health food, and specifically relates to a composition for promoting the balance of gastric microbial flora, and relates to a compatible composition of mannose oligosaccharides, large molecular weight chitosan and chitosan and its preparation method and application. Background technique [0002] 2 Gastric cancer is the third leading cause of cancer-related death worldwide. A large number of current studies believe that Helicobacter pylori (Hp) infection is the most important risk factor for gastric cancer, which can promote precancerous lesions (such as gastric atrophy, intestinal metaplasia, atypical hyperplasia), eventually leading to the occurrence of gastric cancer. Hp infection is very common, the global infection rate is about 50%, and 1-3% of infected people will develop gastric cancer. [0003] 3 At present, the main studies believe that Hp is an important pathogenic factor of chroni...

AI Technical Summary

Problems solved by technology

[0005] 5 The study found that the main causes of gastric microecological imbalance are: (1) During the course of antibiotic treatment, pathogenic bacteria are inhibited, and the survival of normal flora is also destroyed; (2) Different physiological states of the host cause The flora defense barrier is destroyed, which may cause the imbalance of normal flora or transfer to other abnormal parts; (3) Abnormal gastric motility leads to the formation of flora imbalance; (4) Single diet or fiber-free food may affect the bacterial flora. (5) Damage to the immune barrier of the gastrointestinal tract may cause aerobic and anaerobic bacteria to proliferate and disrupt the balance of the flora