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Emulsion containing heparin-like composition

A technology of composition and heparin, which is applied in the field of emulsions containing heparin-like compositions, can solve problems such as imperfect application of heparin-like compositions, and achieve the effects of inhibiting the proliferation of smooth muscle cells, retaining water, and having a good inhibitory effect

Inactive Publication Date: 2019-03-22
沈阳亿欣源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the prior art, the application of the heparinoid composition on the skin, mucous membrane and other action sites is not perfect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1: An emulsion containing a heparinoid composition, including 40 parts of heparin, 59 parts of matrix material, 0.1 part of magnesium stearate, 2.1 parts of transdermal absorbent, 0.02 parts of vitamin C, and 0.1 part of potassium sorbate , 56.1 parts of purified water, and 0.5 parts of collagen.

Embodiment 2

[0024] Example 2: An emulsion containing a heparinoid composition, including 20 parts of heparinoids, 67.8 parts of matrix materials, 10 parts of magnesium stearate, 4 parts of transdermal absorbers, 0.25 parts of vitamin C, and 0.125 parts of potassium sorbate , 50 parts of purified water, 10 parts of collagen.

Embodiment 3

[0025] Example 3: An emulsion containing a heparinoid composition, including 0.5 parts of heparin, 74.6 parts of matrix material, 40 parts of magnesium stearate, 5 parts of transdermal absorbent, 0.5 parts of vitamin C, and 0.2 parts of potassium sorbate , 25.2 parts of purified water, 20 parts of collagen.

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PUM

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Abstract

The invention discloses an emulsion containing a heparin-like composition, and belongs to the field of biotechnology. The emulsion containing the heparin-like composition is characterized by comprising 0.01-80 parts of mucopolysaccharide, 1-90 parts of a matrix material, 0.1-40 parts of an emulsifying agent, 0.01-5 parts of a transdermal absorbent, 0.01-5 parts of an antioxidant, 0.01-5 parts of abacteriostatic agent and 0.01-5 parts of a moisturizing agent. Under a synergistic action of a keratin softening agent and the natural moisturizing agent, the emulsion containing the heparin-like composition can inhibit the excessive growth of collagen fiber and reduce scar formation; the emulsion containing the heparin-like composition can retain moisture on the surface of skin to soften the collagen fiber and enhance the elasticity and has an effect of softening a hypertrophic scar.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to an emulsion containing a heparin-like composition used in medicines, medical equipment, cosmetics, disinfection products and the like. Background technique [0002] Heparinoid is a mucopolysaccharide. In 1948, when Jorpes and Gardell prepared heparin from liver and lung, they obtained a polysaccharide composed of D-glucuronic acid and D-glucosamine. These substances are similar in structure to heparin , but the degree of sulfation is low, and the anticoagulant activity is low, but after more sulfation, its properties change greatly. By combining with the surface of vascular endothelium, it promotes the release of endogenous amino polysaccharides with antithrombotic activity, which can improve local microcirculation, increase blood flow and blood flow velocity, thereby improving intermediate metabolism, promoting skin nutrition supply and waste excretion , play a role in ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/107A61K47/42A61K31/726A61K31/727A61K31/737A61P29/00A61P31/04A61P31/10A61P31/12A61P7/10A61P17/02
CPCA61K9/0014A61K9/107A61K31/726A61K31/727A61K31/737A61K47/42A61P7/10A61P17/02A61P29/00A61P31/04A61P31/10A61P31/12
Inventor 唐财坤关云成李丹钟鑫平王萌炜满国荣朱凯月肖秀梅马立强
Owner 沈阳亿欣源生物科技有限公司
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