Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for preparing taurine

A technology of taurine and ethyl orthosilicate, applied in the preparation of sulfonic acid, organic chemistry and other directions, can solve the problems of long reaction period, potential safety hazards and high cost, and achieve the effects of short production period, convenient operation and low cost

Active Publication Date: 2019-04-12
WANHUA CHEM GRP +1
View PDF7 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The invention relates to a method for preparing taurine, which aims to solve the problems of long reaction cycle and high cost of the existing ethanolamine method; the problems of potential safety hazards and high energy consumption in the method of ethylene oxide technology

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing taurine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Dissolve 4.29g of cetyl ammonium bromide in 50ml of 10wt% ammonia water, stir to dissolve and add NaAlO 2 0.058g, under strong stirring, slowly add 12.3g of ethyl orthosilicate dropwise, and stir for 3 hours to obtain a sol-gel solution, crystallize at 120°C to 125°C for 7 days, filter out the solid, wash until neutral, and then Dry at 105°C-110°C, bake at 800-850°C for 8 hours, press into tablets, grind, and sieve, and take about 8.3g of the 40-70 mesh particle catalyst Al-MCM-41 for use.

[0037] to N 2 After replacing the autoclave, add 95.2g of water and 0.3g of Al-MCM-41 molecular sieve catalyst into the autoclave, add 56.0g of ethylene into the autoclave, pump in 134.4g of sulfur dioxide, start stirring, and heat up to 75°C. 2 The pressure was charged to 7Mpa, the temperature was lowered after 1 hour of reaction, and 159.2 g of 1,1-dioxyethylene thioether was quantified by NMR. The conversion rate of ethylene in the addition reaction was 99.2%, and the selectivi...

Embodiment 2

[0043] N 2 After replacing the autoclave, add 78.6g of water into the autoclave, 0.50g of the Al-MCM-41 type molecular sieve catalyst in Example 1, add 42.0g of ethylene into the autoclave, pump 115.0g of sulfur dioxide into the autoclave, start stirring, and heat up to 80°C, N 2 The pressure was charged to 7.5Mpa, the temperature was lowered after 40 minutes of reaction, and 107.7g of 1,1-dioxyepithione was quantified by NMR. The conversion rate of added ethylene was 95.9%, and the selectivity was 81.3%.

[0044] Transfer the addition reaction solution to the ammonolysis reactor, N 2 Replaced three times, added liquid ammonia 109.4g (6.44mol) and raised the temperature to 120°C. 2 Adjust the pressure to 10Mpa, and cool down after reacting for 50min. LC external standard quantitative taurine 130.2g. The conversion rate of 1,1-dioxyethylene thioether was 99.2%, and the selectivity was 89.7%.

Embodiment 3

[0046] Dissolve cetyl ammonium bromide 3.2g with 10wt% ammonia water 50ml, add Ni(NO 3 ) 2 0.07g, under strong stirring, slowly add 6.1g of ethyl orthosilicate dropwise, and stir for 3 hours to obtain a sol-gel solution, crystallize at 120°C to 125°C for 6 days, filter out the solid, wash until neutral, and then Dry at 105°C-110°C, bake at 800-850°C for 7 hours, press into tablets, grind and sieve, and take 3.4g of Ni-MCM-41 as a 40-70 mesh particle catalyst for use.

[0047] N 2 After replacing the autoclave, add 275g of water and 1.6g of Ni-MCM-41 molecular sieve catalyst into the autoclave, add 156.8g of ethylene into the autoclave, pump 394.2g of sulfur dioxide into the autoclave, start stirring, and heat up to 80°C. 2 Increase the pressure to 8Mpa, cool down after 40 minutes of reaction, and detect 463.7g of 1,1-dioxyethylene thioether. The conversion rate of added ethylene was 97.7%, and the selectivity was 92.1%.

[0048] Transfer the addition reaction solution to ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for preparing taurine. The method comprises the following steps: (1) conducting an addition reaction on ethylene and SO2 to obtain thiirane 1,1-dioxide; and (2) conducting an aminolysis reaction on the thiirane 1,1-dioxide, ammonia and water to obtain taurine. The used raw materials, that is, ethylene, SO2 and ammonia are relatively cheap and readily available, and the used ethylene has no safety hazard of ethylene oxide. In addition, the taurine synthesis method provided by the invention has the advantages of green environment-friendly process, convenient operation, low cost, high yield and easy industrial production.

Description

technical field [0001] The invention relates to the field of organic synthesis, in particular to a preparation method of taurine. technical background [0002] Taurine is also known as taurocholic acid, and its chemical name is 2-aminoethanesulfonic acid (NH 2 CH 2 CH 2 SO 3 H), is a naturally occurring sulfur-containing amino acid. With the in-depth research on the physiological effects and nutritional value of taurine, its application is becoming more and more widespread. It is used in medicine, food, surfactants, pH buffers, etc. have important applications. Taurine widely exists in the organs of humans and mammals, and is one of the most important amino acids. It has special pharmacological effects and physiological functions. In addition, taurine can also be used in the fields of medicine, health care, food, detergent, fluorescent whitening agent, pH buffering agent, etc. It can also be used as a biochemical reagent and an intermediate in other organic synthesis. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07C303/02C07C309/14
CPCC07C303/02C07D331/02C07C309/14
Inventor 郭斌钟子太桂振友孔令晓陈来中蔺海政张静张永振黎源
Owner WANHUA CHEM GRP
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com