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Collagen dressing and preparation method thereof

A sticking and collagen technology, applied in the field of collagen dressing and its preparation, can solve the problems of transportation and storage difficulties, peculiar smell, repulsion, etc., and achieve the effect of promoting wound healing, maintaining activity and promoting absorption

Inactive Publication Date: 2019-04-30
深圳市琉璃光生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the collagen in the collagen dressing is animal-derived collagen, many influencing factors must be considered, such as: the denaturation temperature of animal-derived collagen is 42°C, the preservation of collagen dressings must be strictly controlled below 40°C, and avoid High temperature, which brings some difficulties to transportation and storage, and the product may face deterioration if it is not careful; there is another biggest factor for animal-derived collagen, which is instability. After the product is placed for a period of time, it will appear Adverse reactions such as peculiar smell will bring rejection to patients. Animal-derived collagen has a fatal shortcoming, that is, there are hidden dangers of viruses, such as avian influenza virus, foot-and-mouth disease, mad cow disease virus, mycoplasma and chlamydia, etc. Although collagen dressings can Relieves various symptoms, but there are certain risks

Method used

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  • Collagen dressing and preparation method thereof
  • Collagen dressing and preparation method thereof
  • Collagen dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] A collagen dressing is composed of a collagen compound solution and a non-woven fabric impregnated in the collagen; the collagen compound solution is made of the following components in parts by weight: 1 part of glycerin, 0.5 part of recombinant human collagen, 0.3 part of lactobionic acid, 0.1 part of gluconolactone, 0.05 part of sodium benzoate, 0.2 part of potassium sorbate, 0.2 part of methylparaben and water for injection supplemented to 100 parts.

[0045] The method for preparing this collagen sticking dressing comprises the following steps:

[0046] 1) adding sodium benzoate, potassium sorbate, methyl paraben and glycerin, heating and dissolving to obtain the first feed liquid; adding 20% ​​water for injection to recombinant human collagen, and dissolving it to obtain the second feed liquid;

[0047] 2) Add the remaining amount of water for injection into the emulsification pot, add gluconolactone and lactobionic acid to dissolve, heat to 88°C, keep warm and st...

Embodiment 2

[0052] A collagen dressing is composed of a collagen compound solution and a non-woven fabric impregnated in the collagen; the collagen compound solution is made of the following components in parts by weight: 10 parts of glycerin, 0.05 parts of recombinant human collagen, 0.1 part of lactobionic acid, 0.05 part of gluconolactone, 0.15 part of sodium benzoate, 0.05 part of potassium sorbate, 0.05 part of methylparaben and water for injection to 100 parts.

[0053] The method for preparing this collagen sticking dressing comprises the following steps:

[0054] 1) adding sodium benzoate, potassium sorbate, methyl paraben and glycerin, heating and dissolving to obtain the first feed liquid; adding 10% water for injection to the recombinant human collagen, dissolving it to obtain the second feed liquid;

[0055] 2) Add the remaining amount of water for injection into the emulsification pot, add gluconolactone and lactobionic acid to dissolve, heat to 85°C, keep warm and stir; then...

Embodiment 3

[0060] A collagen dressing is composed of a collagen compound solution and a non-woven fabric impregnated in the collagen; the collagen compound solution is made of the following components in parts by weight: 5 parts of glycerin, 0.5 parts of recombinant human collagen, 0.5 part of lactobionic acid, 0.2 part of gluconolactone, 0.1 part of sodium benzoate, 0.1 part of potassium sorbate, 0.1 part of methylparaben and water for injection supplemented to 100 parts.

[0061] The method for preparing this collagen sticking dressing comprises the following steps:

[0062] 1) adding sodium benzoate, potassium sorbate, methyl paraben and glycerin, heating and dissolving to obtain the first feed liquid; adding 30% water for injection to recombinant human collagen, and dissolving it to obtain the second feed liquid;

[0063] 2) Add the remaining amount of water for injection into the emulsification pot, add gluconolactone and lactobionic acid to dissolve, heat to 90°C, keep warm and sti...

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PUM

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Abstract

The invention discloses a collagen dressing, which is composed of a collagen complex liquid and nonwoven cloth impregnated in collagen. The collagen complex liquid is composed of following componentsin parts by weight: 1 to 10 parts of C3 polyol, 0.01 to 0.5 part of recombinant human-derived collagen, 0.1 to 0.5 part of lactobionic acid, 0.05 to 0.2 part of gluconolactone, 0.2 to 0.5 part of antiseptic, and the balance being injection water, wherein the total parts by weight is 100. The invention also provides a preparation method of the collagen dressing. The collagen dressing is little irritant to the skin, is mild, has a moisturizing function, and can effectively promote the metabolism of cells and healing of wound skins.

Description

technical field [0001] The invention relates to a skin care material, in particular to a collagen dressing and a preparation method thereof. Background technique [0002] With the improvement of the economic base and the improvement of aesthetics, the public's pursuit of beauty has led to an increasing demand for plastic surgery. With the development of medical technology, safer medical aesthetic treatments and more significant effects have also attracted more consumers. These medical cosmetology operations will cause skin inflammation, allergies, scar formation during wound healing, or pigmentation, so repair products are required after surgery. [0003] Collagen is a biopolymer synthesized by fibroblasts. It is the most abundant and widely distributed protein in the human body. It can promote the normal growth of epidermal cells, guide epithelial cells to move into defects, stimulate cell division, and make Its degradation products can be used by newborn cells to synthesi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/32A61L15/20A61L15/44A61L15/42A61L15/46A61L2/08
CPCA61L15/325A61L2/087A61L15/20A61L15/42A61L15/44A61L15/46A61L2202/26A61L2300/23A61L2300/252A61L2300/412
Inventor 刘娣刘磊王泽智林晓婷陈鹏
Owner 深圳市琉璃光生物科技有限公司
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