MOF-derived cu@c catalyst and its preparation method and application

Abstract

The invention discloses a Cu@C catalyst derived from MOF and its preparation method and application. The preparation method comprises the following steps: after fully mixing the mixed solution of benzenetricarboxylic acid and alcohol, the mixed solution of copper salt and water, adding fluorinated The salt is mixed and stirred for self-assembly pre-synthesis to obtain a solution A; then, the solution A is subjected to a rotational crystallization reaction, and after the reaction is finished, it is naturally cooled to obtain a product solution B; then, the product solution B is sequentially purified and dried to obtain Cu‑MOF metal-organic framework; finally, Cu‑MOF metal-organic framework 2 After pyrolysis treatment, the Cu@C catalyst derived from MOF can be obtained. In the present invention, the copper organic framework material is first obtained by rotational crystallization reaction, and then MOF-derived Cu@C catalyst with high catalytic activity is obtained by pyrolysis treatment, and the MOF-derived Cu@C catalyst is applied to catalyze quinolines and H 2 In the selective hydrogenation reaction to prepare tetrahydroquinoline compounds, the conversion rate of quinoline and the yield of tetrahydroquinoline are greatly improved.

Description

technical field [0001] The invention relates to the field of tetrahydroquinoline synthesis catalysts, in particular to a MOF-derived Cu@C catalyst and its preparation method and application. Background technique [0002] 1,2,3,4-Tetrahydroquinoline compound is the structural unit of many quinoline alkaloids, which are widely used in the synthesis of fine chemicals and pharmaceutical intermediates, and have anti-vasodilation, anti-arrhythmic and anti-tumor activities . At present, the methods for industrially synthesizing 1,2,3,4-tetrahydroquinoline compounds mainly include chemical synthesis and catalytic hydrogenation of quinoline. The preparation of 1,2,3,4-tetrahydroquinoline compound by catalytic hydrogenation of quinoline is a relatively simple and feasible way, with few reaction steps and low raw material cost. However, the use of large-scale homogeneous catalysts has problems such as harsh reaction conditions, difficult separation of products and catalysts, and ungu...

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Problems solved by technology

[0006] Because many existing technologies use precious metals as active components, the cost of catalysts remains high, and due to the high activity of precious metal catalysts, the catalyst cannot be recycled multiple times and has poor stability in terms of device start-up stability, operating flexibility and long-term performance of the catalyst. , Precious metals are easily poisoned, making it difficult to maintain long-term operation and other problems

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