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Total-nutrient formula suitable for enterostomy intestine internal absorption for special medicine

A technology of systemic absorption and complete nutrition, which is applied in the direction of food science, etc., can solve the problems of incomplete decomposition of food, complicated formula process, and no unified standard, so as to enhance immune resistance, shorten hospitalization time, and improve the effect of treatment

Inactive Publication Date: 2019-05-21
江苏天美健大自然生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, enteral nutrition (EN) formulas are few and there is no unified standard. They are generally customized for clinicians. The formula process is complicated and easily introduces microorganisms, which can cause intestinal side effects; because enteral nutrition (EN) supports patients to give food Pathway changes, lack of oral amylase, α-glucosidase, pepsin, lipase, etc., lack of related decomposing enzymes will lead to incomplete decomposition of food, and then concentrate in the colon, easily causing indigestion, degenerative diseases, and gastrointestinal tract Environmental changes lead to various diseases, therefore, how to effectively solve the problems existing in the existing technology has become a research problem for many manufacturers

Method used

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  • Total-nutrient formula suitable for enterostomy intestine internal absorption for special medicine
  • Total-nutrient formula suitable for enterostomy intestine internal absorption for special medicine
  • Total-nutrient formula suitable for enterostomy intestine internal absorption for special medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] This formula uses the energy meal alone. It is mainly clinically suitable for daily energy supplementation for patients with gastroenterostomy. The energy meal is brewed with warm water to 250ml, cooled to 35-40°C and injected. The 450kcal energy meal is prepared, and its ingredient ratio is shown in Table 1.

[0023] Table 1 450kcal energy meal preparation plan

[0024] Energy matter

Amount added

Energy matter

Amount added

glucose

15.0g

fish oil powder

5.0g

Crystalline fructose

15.0g

olive oil powder

10.0g

Isomaltooligosaccharide

33.1g

Phytosterols

2.0g

inulin

12.0g

soybean oligopeptide

10.0g

resistant dextrin

12.0g

Fish Collagen Peptides

5.0g

Colostrum freeze-dried powder

675mg

corn peptide

5.0g

yeast

225mg

Probiotics (4.5 billion)

45mg

polyethylene glycol

0.2g

beeswax

0.5g

[0025] Glucose: Sugar source, ...

Embodiment 2

[0039] This formula includes an energy meal (Example 1) and a nutritious meal, which is suitable for daily energy and nutritional supplementation for patients with gastroenterostomy. The intake of the nutritious meal is prepared according to the actual clinical energy intake requirements. In this example, 1 serving of energy meal ( See Table 1) add 4.5 servings of nutritious meal (see Table 2) for preparation, mix the energy meal and nutritious meal, brew in warm water to 250ml, cool to 35-40°C and inject, the preparation ratio of 100kcal nutritious meal is shown in Table 2.

[0040] Table 2 100kcal nutrition package preparation scheme

[0041]

[0042]

Embodiment 3

[0044] The maximum tolerated dose method was used in the experiment, and the formula in Example 2 was used as a sample, and a dosage group of 20 g / kg.bw of the sample was set. SD rats and mice, 20 animals each, half male and half female, were given samples by oral gavage, and the sample solution with a concentration of 0.5g / ml was taken, and the samples were given twice at 20ml / kg bw, and the interval between the two times was After 5 hours, give the sample dose equivalent to 20g / kg bw. After giving the sample solution, observe the general condition, body weight change, poisoning symptoms and death of the mice 14 days later. In the acute toxicity test, after the sample liquid was given, no poisoning symptoms and death were seen in rats and mice during the observation period, the body weight all increased, and no adverse reactions were seen, which proves that this product has no acute toxicity and belongs to safe food.

[0045] Table 3 Acute Oral Toxicity Test Results for Rats ...

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Abstract

The invention relates to a total-nutrient formula suitable for enterostomy intestine internal absorption for special medicine. The formula comprises an energy meal and a nutrient meal. The energy mealcomprises bovine coloctrum, yeast, probiotics and a suspension, and the nutrient meal comprises vitamins and mineral substances; according to the total-nutrient formula suitable for enterostomy intestine internal absorption for special medicine, the formula aims at enterostomy intestine internal auxiliary nutrient supporting, meanwhile, the intestinal environment is regulated, intestinal detoxification is promoted, inflammations caused by enterostomy are resisted, the immunity resistance is enhanced, the treatment period complication occurrence rate can be lowered, the in-hospital time is shortened, the treatment tolerance of patients is improved, and therefore the treatment effect is improved.

Description

technical field [0001] The invention relates to a special medical complete nutritional formula suitable for enteral absorption of gastrostomy, which belongs to the field of preparation formula. Background technique [0002] Patients with malignant tumors of the digestive system are often accompanied by malnutrition. Throat cancer, gastric cancer, intestinal cancer, etc. cause weakened or disordered gastrointestinal absorption function, reduced nutrient absorption capacity, and aggravated gastrointestinal stress response. At present, parenteral nutrition (PN) + enteral nutrition (EN) combined with adjuvant therapy is generally selected, and patients with throat cancer, gastric cancer, intestinal cancer and other digestive tracts who cannot feed are selected to use gastrostomy tube or enterostomy for the patient's intestines. Endogenous nutrition (EN) provides nutritional support during treatment. [0003] Parenteral nutrition (PN) is the intravenous supply of nutritional ele...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/00
Inventor 王荣昌饶安平李玲王玉莹甘露汪普林葛文金郁桦
Owner 江苏天美健大自然生物工程有限公司
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