All-optical fiber laser type selective hypersensitive biochemical sensor

A biochemical sensor and selective technology, applied in the fields of material science, biochemical sensing, and optical sensing, can solve the problems of high price of biochemical sensor fluorescent labeling, difficulty in selective realization, and low sensing accuracy, so as to improve the sensing accuracy. High sensitivity, high signal-to-noise ratio and high reliability

Active Publication Date: 2019-06-18
UNIV OF ELECTRONIC SCI & TECH OF CHINA
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Problems solved by technology

[0007] The purpose of the present invention is to address the above existing problems or deficiencies, in order to solve the problems of the existing biochemical sensor fluorescent markers, such as high price, low sensing accuracy, and difficult selective realization of functionalization, etc., the present invention provides a function-based The all-fiber laser-type selective ultra-sensitive biochemical sensor of oxidized graphene adopts the Fab cavity structure, which increases the number of interactions between the photons in the cavity and the biochemical molecules to be measured in the cavity, and uses functionalized graphene oxide film as the sensitive layer , the cavity is passe

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  • All-optical fiber laser type selective hypersensitive biochemical sensor
  • All-optical fiber laser type selective hypersensitive biochemical sensor
  • All-optical fiber laser type selective hypersensitive biochemical sensor

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[0028] The present invention will be further described below with reference to the drawings and embodiments.

[0029] This embodiment provides an all-fiber laser type selective hypersensitivity biochemical sensor based on functionalized graphene oxide, and its structure is as follows figure 1 As shown, the Fabry-Perot cavity structure includes quartz capillary tubes, functionalized graphene oxide films, gold-plated single-mode optical fibers and other structures; among them:

[0030] The inner diameter of the quartz capillary tube is 126 microns and the length is 1.5 cm. The partially reduced graphene oxide film is deposited on the inner wall of the uniformly distributed graphene oxide dispersion liquid in the cavity through drying-reduction-drying steps. The specific steps are for:

[0031] 1) Vertically immerse a clean quartz capillary into the 1g / L graphene oxide dispersion liquid, and absorb the graphene oxide dispersion liquid by capillary action;

[0032] 2) Place the quartz cap...

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Abstract

The invention belongs to the field of optical sensing, material science and biochemical sensing, relates to an optical sensing and microcavity sensing technology, and provides an all-optical fiber laser type selective hypersensitive biochemical sensor. According to the all-optical fiber laser type selective hypersensitive biochemical sensor of the invention, a functionalized graphene oxide thin film is integrated in a quartz capillary tube so as to be adopted as a sensing dielectric material; and on the basis of the fluorescence resonance transfer characteristics of the functionalized grapheneoxide and advanced heterodyne detection and phase-locked amplification technologies, the functionalized sensing of external biochemical molecules can be realized, and the sensing sensitivity of the biochemical sensor can be greatly improved, and can reach a single-molecule magnitude. The biochemical sensor has high reliability, anti-interference performance and high signal-to-noise ratio. The sensor can be directly integrated into an all-optical fiber system so as to realize the array detection of biochemical sensing.

Description

technical field [0001] The invention relates to the fields of optical sensing, material science and biochemical sensing, relates to optical sensing and microcavity sensing technology, and specifically provides an all-fiber laser type selective ultrasensitive biochemical sensor. Background technique [0002] With the rapid development of optical sensing technology, optical sensors have made great progress. When the light wave propagates in the waveguide, the characteristic parameters (amplitude, phase, polarization state, wavelength, etc.) Various physical quantities are detected on optical sensors. Compared with traditional sensors, optical sensors have the advantages of large amount of information, strong anti-electromagnetic interference, safety and reliability, high sensitivity, and can form a sensor network. Therefore, more and more attention has been paid to optical sensors, and they are widely used in fields such as building structures, instrumentation, biomedicine, ...

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Application Information

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IPC IPC(8): G01N21/64
Inventor 曹忠旭姚佰承秦琛烨郭晏宏饶云江
Owner UNIV OF ELECTRONIC SCI & TECH OF CHINA
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