All-optical fiber laser type selective hypersensitive biochemical sensor

Abstract

The invention belongs to the field of optical sensing, material science and biochemical sensing, relates to an optical sensing and microcavity sensing technology, and provides an all-optical fiber laser type selective hypersensitive biochemical sensor. According to the all-optical fiber laser type selective hypersensitive biochemical sensor of the invention, a functionalized graphene oxide thin film is integrated in a quartz capillary tube so as to be adopted as a sensing dielectric material; and on the basis of the fluorescence resonance transfer characteristics of the functionalized grapheneoxide and advanced heterodyne detection and phase-locked amplification technologies, the functionalized sensing of external biochemical molecules can be realized, and the sensing sensitivity of the biochemical sensor can be greatly improved, and can reach a single-molecule magnitude. The biochemical sensor has high reliability, anti-interference performance and high signal-to-noise ratio. The sensor can be directly integrated into an all-optical fiber system so as to realize the array detection of biochemical sensing.

Description

technical field [0001] The invention relates to the fields of optical sensing, material science and biochemical sensing, relates to optical sensing and microcavity sensing technology, and specifically provides an all-fiber laser type selective ultrasensitive biochemical sensor. Background technique [0002] With the rapid development of optical sensing technology, optical sensors have made great progress. When the light wave propagates in the waveguide, the characteristic parameters (amplitude, phase, polarization state, wavelength, etc.) Various physical quantities are detected on optical sensors. Compared with traditional sensors, optical sensors have the advantages of large amount of information, strong anti-electromagnetic interference, safety and reliability, high sensitivity, and can form a sensor network. Therefore, more and more attention has been paid to optical sensors, and they are widely used in fields such as building structures, instrumentation, biomedicine, ...

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to address the above existing problems or deficiencies, in order to solve the problems of the existing biochemical sensor fluorescent markers, such as high price, low sensing accuracy, and difficult selective realization of functionalization, etc., the present invention provides a function-based The all-fiber laser-type selective ultra-sensitive biochemical sensor of oxidized graphene adopts the Fab cavity structure, which increases the number of interactions between the photons in the cavity and the biochemical molecules to be measured in the cavity, and uses functionalized graphene oxide film as the sensitive layer , the cavity is passed into the mixed solution of the biochemical molecule solution to be tested and the rhodamine dye solution, and the rhodamine molecule is used to compete with the rhodamine molecule attached to the functionalized graphene oxide film to make the rhodamine molecule in the functionalized graphene oxide film. The graphene oxide film falls off, and fluorescence reappears in a free state. After that, the photons are continuously gain-amplified in the F-P resonator to generate laser signals. After photoelectric conversion, they are connected to the electrical sensing test system, using heterodyne detection and phase-locking Amplification technology completes signal extraction and measurement

Images