Method for extracting cannabidiol from industrial hemp

A technology of cannabidiol and industrial hemp, applied in the direction of chemical instruments and methods, preparation of organic compounds, bulk chemical production, etc., can solve the problem of large consumption of organic solvents, low purity of cannabidiol, residual tetrahydrocannabinol and other issues, to achieve the effects of reducing pollution, reliable product safety, and simple preparation process

Inactive Publication Date: 2019-07-05
开远伯盛科技有限公司
View PDF5 Cites 26 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a method for extracting cannabidiol from industrial hemp, so as to solve the problem of low purity of cannabidiol extracted b

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A method for extracting cannabidiol from industrial hemp, comprising the steps of:

[0024] 1) Raw material removal: select the flowers and leaves of industrial hemp to remove organic impurities such as small stems and leaves, as well as inorganic impurities such as stones and plastics;

[0025] 2) Pretreatment: crush the removed industrial hemp flowers and leaves to 40 meshes, and then dry them at 80°C for 2 hours to obtain crushed raw materials with a moisture content of less than 5%;

[0026] 3) Extraction: The pulverized raw materials are subjected to supercritical carbon dioxide extraction. The extraction temperature is 30°C, the pressure is 30MPa, and the extraction time is 3 hours. ;

[0027] 4) Molecular distillation: After heating the cannabidiol primary extract to 90°C, enter the molecular distillation device for distillation, the molecular distillation conditions are heating temperature 80°C, vacuum degree 0.1torr, to obtain cannabidiol enrichment;

[0028]...

Embodiment 2

[0030] A method for extracting cannabidiol from industrial hemp, comprising the following steps:

[0031] 1) Raw material removal: remove the hemp seeds from the hemp bran of industrial hemp, remove organic impurities such as small stems and leaves, and inorganic impurities such as stones and plastics;

[0032] 2) Pretreatment: crush the hemp bran of industrial hemp to 100 mesh, and then dry it at 160° C. for 0.5 hour to obtain a crushed raw material with a moisture content of less than 5%;

[0033] 3) Extraction: Supercritical carbon dioxide extraction is carried out on the pulverized raw materials, the extraction temperature is 50°C, the pressure is 25MPa, the extraction time is 1 hour, and the analysis temperature is 40°C, and the pressure is 5MPa. Obtain the primary extract of cannabidiol;

[0034] 4) Molecular distillation: after heating the primary extract of cannabidiol to 70°C, enter the molecular distillation device for distillation. The molecular distillation condit...

Embodiment 3

[0037] A method for extracting cannabidiol from industrial hemp, comprising the following steps:

[0038] 1) Raw material removal: remove the hemp seeds from the hemp bran of industrial hemp, and remove impurities such as small stems, leaves, stones, plastics, etc.;

[0039] 2) Pretreatment: crush the hemp bran of industrial hemp to 80 mesh, and then dry it at 105°C for 2 hours to obtain a crushed raw material with a moisture content of less than 5%;

[0040] 3) Extraction: The pulverized raw materials are subjected to supercritical carbon dioxide extraction, the extraction temperature is 50°C, the pressure is 15MPa, the extraction time is 4 hours, the analysis temperature is 35°C, and the pressure is 10MPa to obtain the primary extract of cannabidiol;

[0041] 4) Molecular distillation: After heating the primary extract of cannabidiol to 40°C, enter the molecular distillation device for distillation. The molecular distillation conditions are heating temperature 140°C, vacuum ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a method for extracting cannabidiol from industrial hemp. The method includes crushing and drying one or more of flowers, leaves and hemp seed bran of industrial hemp, as rawmaterials, to obtain a crushed raw material the water content of which is not more than 5%; subjecting the crushed raw material to supercritical carbon dioxide extraction to obtain cannabidiol preliminary extract; performing molecular distillation after the cannabidiol preliminary extract is heated to obtain a cannabidiol-enriched product; and subjecting the cannabidiol-enriched product to supercritical fluid chromatography for separation and purification to obtain cannabidiol free of tetrahydrocannabinol and having purity higher than 99%, with macroporous resin or MCI resin or C18 silica gelbeing adopted as a stationary phase, supercritical carbon dioxide being adopted as a mobile phase, and ethanol being adopted as an entrainer. The method is simple in process and easy to operate, and solves problems that cannabidiol extracted by solution leaching methods in the prior art is low in purity, that psychotoxic component tetrahydrocannabinol is left, that a large amount of organic solvents are consumed and that environment is polluted.

Description

technical field [0001] The invention belongs to the field of biotechnology, in particular to a method for extracting cannabidiol from industrial hemp. Background technique [0002] Marijuana (Cannabis sativa L.), also known as hemp or thread hemp, is a plant of the genus Cannabis in the family Moraceae, an annual erect herb. Marijuana contains a toxic component THC (tetrahydrocannabinol), which can make people hallucinogenic and addictive, and can be used as a drug. It was banned for a long time. Due to the high economic and medicinal value of hemp, the raw material hemp exclusively for industrial use is referred to as "industrial hemp". The value of the toxic component tetrahydrocannabinol or directly as a drug can be legally carried out in large-scale cultivation and industrial development and utilization. [0003] The cannabidiol (CBD) component contained in cannabis is a phenolic compound that has not been isolated from other animals and plants. Cannabidiol is a non-ad...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07C39/23C07C37/70
CPCC07C37/004C07C2601/16C07C39/23Y02P20/54
Inventor 孙川
Owner 开远伯盛科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap