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Application of Lignans Compounds in Preparation of Acaricide Drugs

A technology of lignans and compounds, applied in the field of pesticides, to achieve significant practical promotion value, significant social benefits, and good poisonous effect

Active Publication Date: 2021-01-26
SOUTH CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the common populations of spider mites include Panonychus citrus, Tetranychus urticae, Tetranychus cinnabarinus, Panonychus apple, Tetranychus truncates, and Tetranychus hawthorn, etc. They have a wide range of hosts, hidden hazards, common occurrence, and huge losses.

Method used

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  • Application of Lignans Compounds in Preparation of Acaricide Drugs
  • Application of Lignans Compounds in Preparation of Acaricide Drugs
  • Application of Lignans Compounds in Preparation of Acaricide Drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The acaricidal activity of embodiment 1 balusin to adult mite of Tetranychus urticae

[0027] The preparation of alopecia refers to the preparation method in the patent CN201811210133.6. The toxicity of alopecia to Tetranychus urticae was measured by spraying method. The specific method is as follows: acetone is first dissolved in acetone and prepared to a certain concentration mother liquor, and then diluted with 1% Tween aqueous solution to the required concentration; then inoculated the female adult mites of Tetranychus urticae on the kidney bean leaves in a petri dish covered with clean filter paper, sprayed with mites until the leaves are just covered with mist; after the mist evaporates and dries up, cover the dish and place it in the insect culture room for observation, regularly investigate the death situation, and calculate the corrected death rate according to the following formula. The blank control group (CK) was treated with the same solvent and emulsifier,...

Embodiment 2

[0033] Example 2 The acaricidal activity of balusin to nymphs of Tetranychus urticae

[0034] Determination of the biological activity of alopecia to nymphs of Tetranychus urticae, the test method refers to Example 1, and the measurement results are shown in Table 2.

[0035] Table 2 The activity of alopecia to nymphs of Tetranychus urticae

[0036]

[0037] Note: CK column is mortality rate.

[0038] It can be seen from Table 2 that after 10 μg / mL treatment, the 48-h corrected mortality rate of balusin on nymphs of Tetranychus urticae was above 70%, showing a significant acaricidal effect. There was a clear correlation between the mortality rate and the concentration, and the effect of 50 μg / mL baldoxine was greater than that of 200 μg / mL rotenone.

Embodiment 3

[0039] The acaricidal activity of embodiment 3 alopecia to Tetranychus cinnabarinus

[0040] With reference to the method of Example 1, the acaricidal effect of balusin on Tetranychus cinnabarinus was measured, and the results are shown in Table 3.

[0041] Table 3 Toxicity of balusin to female adults of Tetranychus cinnabarinus

[0042]

[0043]

[0044] Note: CK column is mortality rate.

[0045] As can be seen from Table 3, baldrin also has acaricidal activity against Tetranychus cinnabarinus, and the difference in acaricidal activity between baldrin and rotenone at the same concentration (500 μg / mL) is obvious.

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Abstract

The invention discloses the application of lignan compounds in the preparation of acaricide medicine. The structure of the lignan compounds is shown in formula (I); the compound eugenin of the present invention is a chemical component of plant origin, and it has good poisonous effect on various mites, and it is different from the current The acaricides used have different chemical structures and are a new type of acaricide compound, which can create a new field of acaricides; or use it as a lead compound to research and develop a new type of acaricide; It can be mixed with other commonly used acaricides to achieve the effect of preventing and controlling mites, and has significant social, economic and ecological benefits; at the same time, it comes from plants and has a smooth degradation path in nature , will not cause damage to the ecological environment, is safe for non-target organisms, conforms to the development direction of pesticides, and has a good application prospect.

Description

technical field [0001] The invention relates to the technical field of pesticides, and more specifically, relates to the application of lignan compounds in the preparation of acaricide drugs. Background technique [0002] Crop spider mite is a kind of worldwide harmful organism, which can harm the leaves and fruits of fruit trees, vegetables, rice, gardening, flowers and other plants. At present, the common populations of spider mites include Panonychus citrus, Tetranychus urticae, Tetranychus cinnabarinus, Panonychus apple, Tetranychus truncates, and Tetranychus hawthorn, etc. They have a wide range of hosts, hidden hazards, common occurrence, and huge losses. . [0003] Due to the small size of spider mites, the large number of eggs laid, and the rapid reproduction speed, it is easy to develop drug resistance. According to literature reports, typical pest mites such as Tetranychus urticae, Tetranychus cinnabarinus, and Panonychus citrus have developed resistance to almos...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N43/30A01N43/58A01P7/02
CPCA01N43/30A01N43/58
Inventor 黄继光周利娟
Owner SOUTH CHINA AGRI UNIV
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