Microfluidic sample concentration device based on photo-thermal evaporation as well as application method

Abstract

The invention discloses a microfluidic sample concentration device based on photo-thermal evaporation as well as an application method. The microfluidic sample concentration device based on the photo-thermal evaporation comprises a sample solution channel and is characterized in that a porous photo-thermal evaporation layer is arranged above the sample solution channel, a carrier gas channel is arranged above the porous photo-thermal evaporation layer, and a light source is arranged outside the porous photo-thermal evaporation layer; the porous photo-thermal evaporation layer is composed of ahydrophilic porous photo-thermal medium layer and a hydrophobic gas diffusion layer; the hydrophilic porous photo-thermal medium layer produces a capillary suction force on liquid, so that sample solution enters the hydrophilic porous photo-thermal medium layer, meanwhile, the hydrophilic porous photo-thermal medium layer absorbs incident light of the light source and produces photothermal effect,so that the sample solution absorbs heat and is evaporated to produce gas, and then evaporation and concentration on the sample solution are realized; and the hydrophobic gas diffusion layer is of ahydrophobic structure and is located at the upper part of the hydrophilic porous photo-thermal medium layer. The microfluidic sample concentration device disclosed by the invention can be widely applied to the fields of crystal purification, drug synthesis and food engineering.

Description

technical field [0001] The invention relates to the field of microfluidics, in particular to a microfluidic sample concentration device based on photothermal evaporation and a method for using it. Background technique [0002] Microfluidic chips were developed in the field of analytical chemistry in the 1990s, and are playing an increasingly important role as analytical systems, biomedical devices, and chemical and biochemical tools. With its large specific surface area and extremely low sample demand, the microfluidic chip achieves extremely high analysis efficiency. Many microfluidic chips can be processed within a few seconds to tens of seconds, which is much lower than that of conventional laboratories. The required amount of sample is used to complete determination, separation or other more complex operations, which is difficult to achieve by other conventional analysis and detection methods. In addition, compared with traditional analysis and detection methods, microf...

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Problems solved by technology

Furthermore, when the microfluidic chip is used to concentrate and evaporate the sample solution, it is difficult to ensure a reasonable gas-liquid evaporation area due to the small characteristic size of the microchannel, which greatly reduces the evaporation efficiency.

Finally, the overall evaporation efficiency of the microfluidic chip based on evaporative concentration needs to be improved. At present, the more common evaporative concentration device is to load the photothermal conversion medium in the microchannel, such as gold, silver and other precious metals, and control the light beam to carry out the process. The sample solution is heated by irradiation to achieve the effect of concentrated evaporation. Although the photothermal medium mentioned above has a high photothermal conversion efficiency, the efficiency of the evaporation system based on the free gas-liquid interface in the microchannel is still low, and it still has a lot of advantages. big room for improvement

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